SNP information rs12914385

Research and publications:

  18759969   In search of causal variants: refining disease association signals using cross-population contrasts

  19247474   Genome-wide and candidate gene association study of cigarette smoking behaviors

  19628476   Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15

  19654303   Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.

  19836008   A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.

  19859904   Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans

  19955392   Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.

  20418890   Genome-wide meta-analyses identify multiple loci associated with smoking behavior

  20485328   Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

  20548021   Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

  20554942   Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study

  20585100   Genome-wide association studies of cancer.

  20808433   Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population

  21436384   Genetic variability of smoking persistence in African Americans

  21559498   Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk

  21808284   Gender-stratified gene and gene-treatment interactions in smoking cessation.

  21921092   Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.

  21949713   Genetics of sputum gene expression in chronic obstructive pulmonary disease.

  22074863   N-acetyltransferase 2 polymorphisms, tobacco smoking, and breast cancer risk in the breast and prostate cancer cohort consortium.

  22290489   Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.

  22291610   A flexible Bayesian model for studying gene-environment interaction.

  22430809   Association between a genome-wide association study-identified locus and the risk of lung cancer in Japanese population.

  22945651   Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.

  23094028   Genetic association analysis of complex diseases incorporating intermediate phenotype information.

  23689675   Genetic risk for nicotine dependence in the cholinergic system and activation of the brain reward system in healthy adolescents.

  23701534   Genetic instrumental variable studies of effects of prenatal risk factors.

  23870182   Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era.

  24686516   CHRNA3 polymorphism modifies lung adenocarcinoma risk in the Chinese Han population.

  25036316   Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

  25233467   Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.

  25656608   CHRNA3 genetic polymorphism and the risk of lung cancer in the Chinese Han smoking population.

  26831765   Association between two CHRNA3 variants and susceptibility of lung cancer: a meta-analysis.

  26942719   Chromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese Males.

  26948517   Genetic scores of smoking behaviour in a Chinese population.

  27099524   Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome.

  27294413   Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.

  27694844   Fisher's adaptive combination method for joint analysis of multiple phenotypes in association studies.

  28827732   Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.

  29422661   Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics.

  29631575   The genetics of smoking in individuals with chronic obstructive pulmonary disease.

  29688369   The SNPcurator: literature mining of enriched SNP-disease associations.

  29879020   Association analysis of CHRNA3 polymorphisms with schizophrenia in a Chinese Han population: A case-control study.

  31061854   Data on genotype frequency for SNPs associated to age of smoking onset and successful smoking cessation treatment.