SNP information rs12785878

Research and publications:

  20541252   Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

  21441443   Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes

  21828234   Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women

  22112344   Seasonal variation in 25-hydroxyvitamin D concentrations in the cardiovascular health study.

  22613962   Genetic influences on vitamin D status and forearm fracture risk in African American children.

  22629401   Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

  22649517   Polymorphisms related to the serum 25-hydroxyvitamin D level and risk of myocardial infarction, diabetes, cancer and mortality. The Tromsø Study.

  22701574   Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis.

  22801813   The GC, CYP2R1 and DHCR7 genes are associated with vitamin D levels in northeastern Han Chinese children.

  23319826   Vitamin D and mortality: a Mendelian randomization study.

  23456391   Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes.

  23730842   Association of vitamin D serum levels and its common genetic determinants, with severity of liver fibrosis in genotype 1 chronic hepatitis C patients.

  23793229   Association of common gene variants in vitamin D modulating genes and colon cancer recurrence.

  23818875   DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts.

  23979957   Association between vitamin D metabolism gene polymorphisms and risk of islet autoimmunity and progression to type 1 diabetes: the diabetes autoimmunity study in the young (DAISY).

  24184224   Polymorphisms in genetics of vitamin D metabolism confer susceptibility to ocular Behçet disease in a Chinese Han population.

  24516573   Vitamin D levels vary during antiviral treatment but are unable to predict treatment outcome in HCV genotype 1 infected patients.

  24642724   Effect of polymorphisms in the NADSYN1/DHCR7 locus (rs12785878 and rs1790349) on plasma 25-hydroxyvitamin D levels and coronary artery disease incidence.

  24663808   A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness).

  24868205   Vitamin D Binding Protein Impact on 25-Hydroxyvitamin D Levels under Different Physiologic and Pathologic Conditions.

  25281353   Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study.

  25405862   Vitamin D insufficiency in Arabs and South Asians positively associates with polymorphisms in GC and CYP2R1 genes.

  25738688   Meta-analysis on vitamin D receptor and cancer risk: focus on the role of TaqI, ApaI, and Cdx2 polymorphisms.

  26038244   Genetic Variation in CYP2R1 and GC Genes Associated With Vitamin D Deficiency Status.

  26141257   Low vitamin D status is associated with more depressive symptoms in Dutch older adults.

  26149120   Vitamin D Deficiency in Uygurs and Kazaks Is Associated with Polymorphisms in CYP2R1 and DHCR7/NADSYN1 Genes.

  26275945   Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study.

  26416604   Vitamin D metabolism-related genetic variants, dietary protein intake and improvement of insulin resistance in a 2 year weight-loss trial: POUNDS Lost.

  26446360   Mendelian randomization studies of biomarkers and type 2 diabetes.

  26872154   Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants.

  27215954   Investigating causality in the association between 25(OH)D and schizophrenia.

  27331016   ERBB3-rs2292239 as primary type 1 diabetes association locus among non-HLA genes in Chinese.

  27366029   Vitamin D deficiency in patients with liver cirrhosis.

  27625044   Genetically Low Vitamin D Levels, Bone Mineral Density, and Bone Metabolism Markers: a Mendelian Randomisation Study.

  27756067   Determinants of Neonatal Vitamin D Levels as Measured on Neonatal Dried Blood Spot Samples.

  28296915   Genetic variation in the vitamin D pathway CYP2R1 gene predicts sustained HBeAg seroconversion in chronic hepatitis B patients treated with pegylated interferon: A multicenter study.

  28415985   Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients.

  28575224   Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants.

  28594127   There is no clear support for a role of vitamin D in Parkinson's disease: a Mendelian randomized trial.

  28938476   Fetal and Maternal Genetic Variants Influencing Neonatal Vitamin D Status.

  29038561   Vitamin D and cognitive function: A Mendelian randomisation study.

  29089348   Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.

  29291743   SNPs related to vitamin D and breast cancer risk: a case-control study.

  29514138   Effects of Gene Variants Controlling Vitamin D Metabolism and Serum Levels on Hepatic Steatosis.

  29718335   Negative effect of vitamin D on kidney function: a Mendelian randomization study.

  29718904   Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

  29748306   Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study.

  29761652   Vitamin D status and associated genetic polymorphisms in a cohort of UK children with non-alcoholic fatty liver disease.

  29892565   The genetic determinants of circulating C3-epimers of 25-hydroxyvitamin D.

  29925546   Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study.

  29937467   Association among genetic variants in the vitamin D pathway and circulating 25-hydroxyvitamin D levels in Korean adults: results from the Korea National Health and Nutrition Examination Survey 2011-2012.

  30139224   The Association of PNPLA3, COX-2 and DHCR7 Polymorphisms with Advanced Liver Fibrosis in Patients with HCV Mono- Infection and HCV/HIV Co-Infection.

  30405883   Variability in genes regulating vitamin D metabolism is associated with vitamin D levels in type 2 diabetes.

  30465296   Potential causal associations of serum 25-hydroxyvitamin D with lipids: a Mendelian randomization approach of the HUNT study.

  30475961   Genetically determined vitamin D levels and change in bone density during a weight-loss diet intervention: the Preventing Overweight Using Novel Dietary Strategies (POUNDS Lost) Trial.

  30609725   Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts.

  30716477   There is no association between vitamin D status and the risk of developing Barrett's esophagus or esophageal adenocarcinoma: a Mendelian randomized trial.

  30796319   Vitamin D Receptor Polymorphism and DHCR7 Contribute to the Abnormal Interplay Between Vitamin D and Lipid Profile in Rheumatoid Arthritis.

  31030503   Vitamin D-Binding protein Gene Polymorphism Predicts Pegylated Interferon-Related HBsAg Seroclearance in HBeAg-Negative Thai Chronic Hepatitis B Patients: A Multicentre Study.

  31104167   Influence of genetic variation in the vitamin D pathway on plasma 25-hydroxyvitamin D(3) levels and survival among patients with metastatic colorectal cancer.

  31218665   Is there a causal relationship between vitamin D and melanoma risk? A Mendelian randomization study.

  31357732   Association of Vitamin D Pathway Genetic Variation and Thyroid Cancer.

  31475028   Host Genetic Determinants of Hepatitis B Virus Infection.

  31814925   Association of circulating 25-hydroxyvitamin D levels with hypertension and blood pressure values in Korean adults: A Mendelian randomization study on a subset of the Korea National Health and Nutrition Survey 2011-2012 population.

  31881507   Variants in gene encoding for vitamin D binding protein were associated with leukocyte telomere length: The Pró-Saúde Study.

  31959263   Vitamin D-related genes and cardiometabolic markers in healthy children: a Mendelian randomisation study.

  32289634   Effect of genetic factors on the response to vitamin D(3) supplementation in the VIDARIS randomized controlled trial.

  32517587   Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.

  32593521   Higher levels of 25-hydroxyvitamin D are associated with an increased risk of Bechsche's disease.

  32764491   Vitamin D Pathway Genetic Variation and Type 1 Diabetes: A Case-Control Association Study.

  33145299   Association of circulating 25-Hydroxyvitamin D and its related genetic variations with hepatocellular carcinoma incidence and survival.

  33245439   A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder.

  33553043   Vitamin D pathway-related gene polymorphisms and their association with metabolic diseases: A literature review.

  33763108   Whole Genome Interpretation for a Family of Five.

  33961971   Vitamin D pathway gene polymorphisms, vitamin D level, and cytokines in children with type 1 diabetes.

  34093899   Association of Polymorphisms in Vitamin D-Metabolizing Enzymes DHCR7 and CYP2R1 with Cancer Susceptibility: A Systematic Review and Meta-Analysis.

  34150833   Association of Vitamin D, Zinc and Selenium Related Genetic Variants With COVID-19 Disease Severity.

  34187381   Association of serum 25-hydroxyvitamin D with metabolic syndrome and type 2 diabetes: a one sample Mendelian randomization study.

  34315477   A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans.

  34464857   Low vitamin D exposure and risk of nasopharyngeal carcinoma: Observational and genetic evidence from a multicenter case-control study.

  34675344   Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVID-19 disease severity.

  34755103   Determinants of circulating 25-hydroxyvitamin D concentration and its association with musculoskeletal health in midlife: Findings from the Hertfordshire Cohort Study.

  34959812   Vitamin D and Type 1 Diabetes Risk: A Systematic Review and Meta-Analysis of Genetic Evidence.

  35256680   Sunlight, dietary habits, genetic polymorphisms and vitamin D deficiency in urban and rural infants of Bangladesh.

  35474389   Maternal and Fetal Genetic Variation in Vitamin D Metabolism and Umbilical Cord Blood 25-Hydroxyvitamin D.

  35720397   Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.

  35760298   Genetic control of serum 25(OH)D levels and its association with ethnicity.

  36012386   Vitamin D-Related Genetic Variations and Nonalcoholic Fatty Liver Disease: A Systematic Review.