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SNP information rs11868035

RS11868035

Normal allele: AA

Causes increased plasma free fatty acids, predisposing to early cognitive impairment in type 2 diabetes mellitus.

Polymorphism rs11868035 is related to topics like this:

Type 2 diabetes genetic

Type 2 diabetes is the most prevalent and impactful subtype of diabetes worldwide, affecting around...

Parkinson is a genetic disease

A disorder that progresses gradually within the nervous system is known as Parkinson's disease. It...


Research and publications:

  17019602   Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes.

  18192539   Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects.

  18692268   Association of sterol regulatory element-binding protein-1c gene polymorphism with type 2 diabetes mellitus, insulin resistance and blood lipid levels in Chinese population.

  18936756   Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples.

  22086882   No association between Parkinson disease alleles and the risk of melanoma.

  23285067   Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts.

  23985808   Impact of sterol regulatory element-binding factor-1c polymorphism on incidence of nonalcoholic fatty liver disease and on the severity of liver disease and of glucose and lipid dysmetabolism.

  24329191   Pharmacogenomics of sterol synthesis and statin use in schizophrenia subjects treated with antipsychotics.

  24514572   Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.

  25028659   The gene-gene interaction of INSIG-SCAP-SREBP pathway on the risk of obesity in Chinese children.

  26965314   Gene polymorphisms associated with non-alcoholic fatty liver disease and coronary artery disease: a concise review.

  27076879   Association Study Between Metabolic Syndrome and rs8066560 Polymorphism in the Promoter Region of Sterol Regulatory Element-binding Transcription Factor 1 Gene in Iranian Children and Adolescents.

  27572914   Lack of association between SREBF-1c gene polymorphisms and risk of non-alcoholic fatty liver disease in a Chinese Han population.

  27771555   SREBF-2 polymorphism influences white matter microstructure in bipolar disorder.

  30600310   Impact of polymorphism of selected genes on the diagnosis of type 2 diabetes in patients with obstructive sleep apnea.

  31490983   SREBF1c and SREBF2 gene polymorphisms are associated with acute coronary syndrome and blood lipid levels in Mexican population.

  34151809   Elevated Plasma Free Fatty Acid Susceptible to Early Cognitive Impairment in Type 2 Diabetes Mellitus.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

  28927418   A systematic review and integrative approach to decipher the overall molecular link between levodopa response and Parkinson's disease.

  21738487   Genome-wide internet-based association study identifies two new loci and a significant genetic component of Parkinson's disease.

  22531747   Study of the association between two novel single nucleotide polymorphisms and sporadic Parkinson's disease in the Chinese Han population.

  22892372   Using genome-wide integrated trait analysis to quantify “missing heritability” in Parkinson's disease.

  27494614   Big data predictive analytics: Parkinson's disease research using large, complex, heterogeneous, inconsistent, multi-source, and incomplete observations.

  29128630   Analysis of the association of SNP rs11868035 in SREBF1 with sporadic Parkinson's disease, sporadic amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population.

  30231795   The SREBF1 rs11868035-G/A gene polymorphism is associated with susceptibility to Parkinson's disease in a Chinese population.

  30581395   Improving cognitive functions to increase the effectiveness of treatment for schizophrenia: the impact of metabolic syndrome on the outcome of cognitive rehabilitation.

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