Research and publications:
15911586 Effects of natural selection on interpopulation divergence at polymorphic sites in human protein-coding Loci.
16172230 Risk of testicular germ cell cancer in relation to variation in maternal and offspring cytochrome p450 genes involved in catechol estrogen metabolism.
16412218 Multilocus analysis of SNP and metabolic data within a given pathway
16949388 CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal.
16949389 Vasomotor symptom prevalence is associated with polymorphisms in sex steroid-metabolizing enzymes and receptors.
17116718 Dietary phytoestrogen intake is associated with reduced colorectal cancer risk
17160896 Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants.
17224914 Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer.
17548691 Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race.
17615053 Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.
18187806 Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel.
18191955 Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools
18268125 Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns.
18470941 Mutations in CYP1B1 cause primary congenital glaucoma by reduction of either activity or abundance of the enzyme.
18544568 CYP1B1 variants are associated with prostate cancer in non-Hispanic and Hispanic Caucasians.
18628428 Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer.
18632753 Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
18763031 CYP1A1 and CYP1B1 genetic polymorphisms and uterine leiomyoma risk in Chinese women.
18805939 Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis
18936436 Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994
18989382 Novel CYP1B1 mutations in consanguineous Pakistani families with primary congenital glaucoma.
18990750 Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.
18992148 Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study
19015200 Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.
19127255 Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium.
19168589 Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China.
19174490 Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women.
19214745 Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologists.
19293312 Association of CYP1B1 haplotypes and breast cancer risk in Caucasian women.
19338043 Genetic polymorphisms in glutathione S-transferases and cytochrome P450s, tobacco smoking, and risk of non-Hodgkin lymphoma.
19414505 CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences.
19479063 Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.
19582785 Methods for detecting interactions between genetic polymorphisms and prenatal environment exposure with a mother-child design.
19597567 Molecular analysis of CYP1B1 in Omani patients with primary congenital glaucoma: a pilot study.
19630952 Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women.
19679043 African American-preponderant single nucleotide polymorphisms (SNPs) and risk of breast cancer.
19730035 CYP1B1 genotype and risk of cardiovascular disease, pulmonary disease, and cancer in 50,000 individuals.
19736056 Associations of common variants in genes involved in metabolism and response to exogenous chemicals with risk of multiple myeloma.
19754948 Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study.
19822571 Genetic variations in xenobiotic metabolic pathway genes, personal hair dye use, and risk of non-Hodgkin lymphoma.
19860743 Effect of gene-environment Interactions on mental development in African American, Dominican, and Caucasian mothers and newborns.
19895167 CYP1B1 gene polymorphism modifies pancreatic cancer risk but not survival.
20029944 Genetic polymorphisms in the metabolic pathway and non-Hodgkin lymphoma survival.
20057908 Identification of four novel cytochrome P4501B1 mutations (p.I94X, p.H279D, p.Q340H, and p.K433K) in primary congenital glaucoma patients.
20131310 Genetic polymorphisms in cytochrome P450s, GSTs, NATs, alcohol consumption and risk of non-Hodgkin lymphoma.
20357209 Molecular genetic studies of gene identification for osteoporosis: the 2009 update
20395011 The CYP1B1 Leu432Val polymorphism contributes to lung cancer risk: evidence from 6501 subjects.
20436251 Xenobiotic metabolizing genes, meat-related exposures, and risk of advanced colorectal adenoma.
20505544 Effect of hormone metabolism genotypes on steroid hormone levels and menopausal symptoms in a prospective population-based cohort of women experiencing the menopausal transition.
20701755 Variant alleles of the CYP1B1 gene are associated with colorectal cancer susceptibility.
20734064 A large-scale candidate gene association study of age at menarche and age at natural menopause.
20831431 Factors that may influence the experience of hot flushes by healthy middle-aged women.
20878130 Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population.
20889730 Cytochrome P450 1B1 gene polymorphisms as predictors of anticancer drug activity: studies with in vitro models.
20937634 Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk.
21072184 Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.
21081473 Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia.
21092186 Polymorphisms in genes involved in the estrogen pathway and mammographic density.
21107304 Genetic determinants of mycophenolate-related anemia and leukopenia after transplantation.
21139974 Tag SNPs detect association of the CYP1B1 gene with primary open angle glaucoma.
21254355 Smoking, the xenobiotic pathway, and clubfoot.
21270648 Renal cancer risk and occupational exposure to polycyclic aromatic hydrocarbons and plastics.
21474949 Xenobiotic metabolizing genes, meat-related exposures, and risk of advanced colorectal adenoma.
21514219 Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence
21532841 Interaction of CYP1B1, cigarette-smoke carcinogen metabolism, and lung cancer risk.
21567099 Estrogen metabolism genotypes, use of long-term hormone replacement therapy and risk of postmenopausal breast cancer.
21618522 Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.
21674184 Current evidence on the relationship between CYP1B1 polymorphisms and lung cancer risk: a meta-analysis.
21683070 Polymorphisms in CYP1B1 modify the risk of idiopathic male infertility with abnormal semen quality.
21708280 Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis
21850185 Mutation spectrum of CYP1B1 and MYOC genes in Korean patients with primary congenital glaucoma.
21894447 Are centenarians genetically predisposed to lower disease risk?
21992066 Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers.
22190224 CYP1B1 Leu432Val polymorphism and colorectal cancer risk among Caucasians: a meta-analysis.
22301281 Genetic variants in carcinogen-metabolizing enzymes, cigarette smoking and pancreatic cancer risk.
22311237 Gene-environment interactions on growth trajectories.
22327650 Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: a meta-analysis.
22418777 Estrogen-related genes and their contribution to racial differences in breast cancer risk.
22466345 Joint effects of smoking and gene variants involved in sex steroid metabolism on hot flashes in late reproductive-age women.
22509109 No association of genetic polymorphisms in CYP1B1 with primary open-angle glaucoma: a meta- and gene-based analysis.
22527101 CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel.
22549291 Association of variants in estrogen-related pathway genes with prostate cancer risk.
22610071 Polymorphisms in carcinogen metabolism enzymes, fish intake, and risk of prostate cancer.
22633539 Selected polymorphisms in sex hormone-related genes, circulating sex hormones and risk of endometrial cancer.
22645715 Xenobiotic metabolizing gene variants and renal cell cancer: a multicenter study.
22655262 Exposure to Polycyclic Aromatic Hydrocarbons Among Never Smokers in Golestan Province, Iran, an Area of High Incidence of Esophageal Cancer - a Cross-Sectional Study with Repeated Measurement of Urinary 1-OHPG in Two Seasons.
22674470 Phenanthrene metabolism in smokers: use of a two-step diagnostic plot approach to identify subjects with extensive metabolic activation.
22822096 Red meat and poultry, cooking practices, genetic susceptibility and risk of prostate cancer: results from a multiethnic case-control study.
22992668 Pharmacogenomics knowledge for personalized medicine.
22994552 Maternal variation in EPHX1, a xenobiotic metabolism gene, is associated with childhood medulloblastoma: an exploratory case-parent triad study.
23000097 Polymorphisms of catechol estrogens metabolism pathway genes and breast cancer risk in Mexican women.
23015320 Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps.
23139742 Functional analyses of endometriosis-related polymorphisms in the estrogen synthesis and metabolism-related genes.
23168575 Candidate gene linkage approach to identify DNA variants that predispose to preterm birth.
23175176 Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype.
23283740 Common genetic variation in CYP1B1 is associated with concentrations of T₄, FT₃ and FT₄ in the sera of polycystic ovary syndrome patients.
23299405 Interaction of cigarette smoking and carcinogen-metabolizing polymorphisms in the risk of colorectal polyps.
23370603 Catechol-O-methyltransferase and cytochrome P-450 1B1 polymorphisms and endometrial cancer risk: a meta-analysis.
23424626 Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study.
23433810 Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia.
