SNP information rs4986790

Research and publications:

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  16820586   Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery

  16846490   Lemierre's syndrome and genetic polymorphisms: case report

  16859562   Do host genetic traits in the bacterial sensing system play a role in the development of Chlamydia trachomatis-associated tubal pathology in subfertile women?

  16954131   Toll-like receptor 4 gene polymorphisms and myocardial infarction: no association in a Caucasian population.

  17062130   Polymorphisms within inflammatory genes and colorectal cancer.

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17592300   Genetic polymorphisms and the risk of infection following esophagectomy. positive association with TNF-alpha gene -308 genotype

  17668374   Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants

  17699831   Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study.

  17708757   Genome bioinformatic analysis of nonsynonymous SNPs.

  17827388   Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.

  17952073   Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

  18062835   Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases.

  18172114   Comprehensive analysis of the candidate genes CCL2, CCR2, and TLR4 in age-related macular degeneration.

  18298826   Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol.

  18307517   Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans

  18325643   Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results.

  18382655   Maternal TLR4 and NOD2 gene variants, pro-inflammatory phenotype and susceptibility to early-onset preeclampsia and HELLP syndrome.

  18396467   Genetic variation and haplotype structures of innate immunity genes in eastern India.

  18422738   Study of Toll-like receptor gene loci in sarcoidosis.

  18549840   Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke.

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18635889   Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.

  18753640   Toll-like receptor 3 and geographic atrophy in age-related macular degeneration.

  18936436   Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

  18975326   Toll-like receptor 2 variants are associated with acute reactive arthritis.

  19029192   A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma.

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19085953   Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses.

  19131814   Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: a cohort study

  19134200   No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.

  19267370   Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II

  19277200   Toll-like receptor 4 (TLR4) and typhoid fever in Vietnam.

  19337058   CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations.

  19505919   Toll-like receptor signaling pathway variants and prostate cancer mortality

  19531762   Association between toll-like receptor 4 gene polymorphism and biopsy-proven giant cell arteritis.

  19543401   Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.

  19554026   Genetic association of Toll-like receptor 4 with cervical cytokine concentrations during pregnancy.

  19586676   Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection.

  19628747   Toll-like receptor polymorphisms and age-related macular degeneration: replication in three case-control samples.

  19922963   A functional nonsynonymous toll-like receptor 4 gene polymorphism is associated with metabolic syndrome, surrogates of insulin resistance, and syndromes of lipid accumulation.

  20011079   Lack of association between toll-like receptor 4 gene polymorphisms and sarcoidosis-related uveitis in Japan.

  20016852   Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.

  20026892   Association of the Toll-like receptor gene with Crohn's disease in Koreans.

  20200442   Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.

  20386472   Cancer and inflammation: promise for biologic therapy.

  20392289   Genetic associations in type I interferon related pathways with autoimmunity.

  20525286   Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.

  20577092   Genetic variation of innate immune genes in HIV-infected african patients with or without oropharyngeal candidiasis.

  20617897   Polymorphisms in maternal and fetal genes encoding for proteins involved in extracellular matrix metabolism alter the risk for small-for-gestational-age.

  20646321   Toll-like receptor (TLR) and nucleosome-binding oligomerization domain (NOD) gene polymorphisms and endometrial cancer risk.

  20671584   Toll-like receptor 4 gene polymorphisms show no association with the risk of clinical or angiographic restenosis after percutaneous coronary intervention.

  20818961   Inflammatory mediators gene polymorphisms in preeclampsia.

  21045241   Age-related macular degeneration: genetic and environmental factors of disease.

  21054877   Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994

  21079743   Interaction of Crohn's disease susceptibility genes in an Australian pediatric cohort.

  21081146   Impact of Toll-like receptor 4 polymorphisms on risk of cancer.

  21159925   Toll-like receptor 4 gene (TLR4), but not TLR2, polymorphisms modify the risk of tonsillar disease due to Streptococcus pyogenes and Haemophilus influenzae.

  21160888   Genetic predisposition to Helicobacter pylori-induced gastric precancerous conditions

  21179534   Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.

  21214494   Molecular pathogenesis of endometriosis; Toll-like receptor-4 A896G (D299G) polymorphism: a novel explanation.

  21219635   Variants in the Toll-interacting protein gene are associated with susceptibility to sepsis in the Chinese Han population.

  21298446   Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study.

  21306745   Polymorphisms in Toll-like receptor 4 are associated with factors of the metabolic syndrome and modify the association between dietary saturated fat and fasting high-density lipoprotein cholesterol.

  21333900   The role of genetics in IBS

  21385363   Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study

  21466684   Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients.

  21483748   Influence of polymorphisms in innate immunity genes on susceptibility to invasive aspergillosis after stem cell transplantation

  21563195   Genetic variation in the toll-like receptor 4 and prostate cancer incidence and mortality.

  21609220   Genetics of age-related macular degeneration: current concepts, future directions.

  21756351   Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes.

  21776015   Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis.

  21837802   Confirmation of an association between single nucleotide polymorphisms in the VDR gene with respiratory syncytial virus related disease in South African children.

  21852947   Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.

  21867552   Host candidate gene polymorphisms and clearance of drug-resistant Plasmodium falciparum parasites.

  21920464   Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer.

  21931695   Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival.

  21955043   Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi-center cohort.

  22022564   Nasopharyngeal bacterial colonization and gene polymorphisms of mannose-binding lectin and toll-like receptors 2 and 4 in infants.

  22194275   Histological and genetic studies in patients with bicuspid aortic valve and ascending aorta complications.

  22238472   Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease.

  22251849   The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study.

  22280494   Rapid multiplex high resolution melting method to analyze inflammatory related SNPs in preterm birth.

  22300618   Toll-like 4 receptor variant, Asp299Gly, and reduced risk of hemorrhagic cystitis after hematopoietic stem cell transplantation.

  22301633   Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.

  22324898   Genetics of immunological and inflammatory components in age-related macular degeneration.

  22348075   Influence of common non-synonymous Toll-like receptor 4 polymorphisms on bronchopulmonary dysplasia and prematurity in human infants.

  22359464   Are Toll-like receptor gene polymorphisms associated with prostate cancer?

  22360682   Lack of association between TLR4 rs4986790 polymorphism and risk of cardiovascular disease in patients with rheumatoid arthritis.

  22427729   Inherited variation in pattern recognition receptors and cancer: dangerous liaisons?

  22494793   Innate immunity gene single nucleotide polymorphisms and otitis media.

  22524430   Genetics of longevity. data from the studies on Sicilian centenarians.

  22529866   Genetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection.

  22573572   Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in autophagy-related genes (GOIA II study).

  22615793   Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population.

  22645142   Variants of Toll-like receptor 4 predict cardiac recovery in patients with dilated cardiomyopathy.

  22662111   Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis.

  22691414   Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children.

  22740716   Toll-like receptor and hepatitis B virus clearance in chronic infected patients: a long-term prospective cohort study in Taiwan.