SNP information rs4810485

Research and publications:

  18794853   Common variants at CD40 and other loci confer risk of rheumatoid arthritis

  19159017   STAT2*C related genotypes and allele but not TLR4 and CD40 gene polymorphisms are associated with higher susceptibility for asthma.

  19180477   Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations

  19435719   Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study

  19644859   Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis.

  19674979   Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

  19898481   Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

  20018027   Conditional analysis of the major histocompatibility complex in rheumatoid arthritis.

  20075733   Recent advances in the genetics of rheumatoid arthritis.

  20219786   The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.

  20233754   Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.

  20309874   Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.

  20426808   AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm.

  20439292   Genetic variants in the prediction of rheumatoid arthritis.

  20444755   Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.

  20453842   Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

  20461788   Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients.

  20498205   Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.

  20510233   Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21120996   Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans.

  21156761   A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

  21211616   Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.

  21645569   A CD40 and an NCOA5 gene polymorphism confer susceptibility to psoriasis in a Southern European population: a case-control study.

  21765104   Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.

  21912605   Association of CD40 gene polymorphisms with sporadic breast cancer in Chinese Han women of Northeast China.

  21914625   A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis.

  21931699   Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset.

  21980439   A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis.

  22087016   CD40 gene polymorphism increases the risk of Behçet disease but not Vogt-Koyanagi-Harada syndrome in a Chinese Han population.

  22190364   Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

  22328738   Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.

  22508400   Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) identifies common susceptibility loci with rheumatoid arthritis.

  22645426   CD40 Gene polymorphisms associated with susceptibility and coronary artery lesions of Kawasaki disease in the Taiwanese population.

  22661644   Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.

  22731751   Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis.

  22753952   Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

  23049851   Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis.

  23121884   Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.

  23166616   Study of association of CD40-CD154 gene polymorphisms with disease susceptibility and cardiovascular risk in Spanish rheumatoid arthritis patients.

  23251581   Meta-analysis of 125 rheumatoid arthritis-related single nucleotide polymorphisms studied in the past two decades.

  23256180   Association of genetic polymorphisms in CD40 with susceptibility to SLE in the Korean population.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  23678157   Integrative analyses for functional mechanisms underlying associations for rheumatoid arthritis.

  24068971   Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

  24449572   Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

  24828072   The SNP rs1883832 in CD40 gene and risk of atherosclerosis in Chinese population: a meta-analysis.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  25305459   Lack of association between CD40 polymorphisms and acute rejection in German liver transplant recipients.

  25373542   Associations of polymorphisms rs4810485 and rs1883832 of the CD40 gene with susceptibility and clinical manifestations of Behçet's disease.

  25908480   Associations between the functional CD40 rs4810485 G/T polymorphism and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis.

  26474561   The association of CD40 polymorphisms with CD40 serum levels and risk of systemic lupus erythematosus.

  26843965   Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis.

  27014188   Analysis of genetic susceptibility to Graves' disease in a cohort of patients of Italian origin.

  27073425   Candidate gene polymorphisms and risk of psoriasis: A pilot study.

  27578014   Association of CD40 Gene Polymorphisms with Susceptibility to Neuromyelitis Optica Spectrum Disorders.

  27722794   Gene-gene interaction between CD40 and CD226 gene on systemic lupus erythematosus in the Chinese Han population.

  27875792   Investigation of CD40 gene rs4810485 and rs1883832 mutations in patients with recurrent aphthous stomatitis.

  28181356   CD40 polymorphism in cervical carcinoma in a subset of Malaysian population.

  28320398   Single nucleotide polymorphisms in the CD40 gene associate with the disease susceptibility and severity in knee osteoarthritis in the Chinese Han population: a case-control study.

  29214033   Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.

  29361022   Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells.

  30511624   Investigation of association between CD40 current gene variants (rs4810485, rs1883832 and rs3765459) and serum CD154 protein levels in Iranian migraineurs.

  30878028   Potential Markers of Autoimmune Diseases, Alleles rs115662534(T) and rs548231435(C), Disrupt the Binding of Transcription Factors STAT1 and EBF1 to the Regulatory Elements of Human CD40 Gene.

  30924686   Associations of rs1883832 and rs4810485 polymorphisms of CD40 gene with myocardial infarction in the Tunisian population.

  31183392   Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome.

  31217170   Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.

  31570051   Association between CD40 polymorphisms and systemic lupus erythematosus and correlation between soluble CD40 and CD40 ligand levels in the disease: a meta-analysis.

  31615434   CD40 polymorphisms were associated with HCV infection susceptibility among Chinese population.

  31642196   Association of soluble CD40 levels with -1 C > T CD40 polymorphism and chronic kidney disease in systemic lupus erythematosus.

  32018016   Impact of CD40 gene polymorphisms on the risk of immune thrombocytopenic purpura.

  32507051   IRAK1 Gene Polymorphism in Rheumatoid Arthritis.

  32831971   Investigating the GWAS-Implicated Loci for Rheumatoid Arthritis in the Pakistani Population.

  32929287   Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.

  33374413   Tracking the genetic susceptibility of B-cell non-Hodgkin's lymphomas based on genome-wide association studies.

  33968033   Association of CD40 Gene Polymorphisms With Systemic Lupus Erythematosus and Rheumatoid Arthritis in a Chinese Han Population.

  35088123   Genetics of rheumatoid arthritis.

  35107652   A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis.

  35920091   Association of CD40 gene polymorphisms and immune thrombocytopenic purpura in the adult Egyptian population.