SNP information rs3851179

Research and publications:

  19734902   Genome-wide association study identifies CLU and PICALM variants associated with Alzheimer's disease.

  20236449   Genetics of Alzheimer disease in the pre- and post-GWAS era.

  20451875   Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Key goals, progress, and genetics roadmap.

  20460622   Genome-wide analysis of genetic loci associated with Alzheimer disease

  20554627   Replication of CLU, CR1, and PICALM associations with alzheimer disease.

  20558387   Genetic variation and neuroimaging measures in Alzheimer disease.

  20570404   Association of CLU and PICALM variants with Alzheimer's disease.

  20594621   Genetic architecture of Alzheimer's disease: beyond APP, PSEN and APOE.

  20697030   Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.

  20738160   Association analysis between the rs11136000 single nucleotide polymorphism in clusterin gene, rs3851179 single nucleotide polymorphism in clathrin assembly lymphoid myeloid protein gene and the patients with schizophrenia in the Chinese populati

  20739100   Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old.

  20951388   Genetic association of PICALM polymorphisms with Alzheimer's disease in Han Chinese.

  21059989   Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals.

  21124753   Alzheimer's disease: diagnosis, prognosis and path to prevention.

  21132329   Study of 15 candidate genes responsible for late-onset Alzheimer's disease.

  21152065   A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis.

  21297266   Implication of a genetic variant at PICALM in Alzheimer’s disease patients and centenarians.

  21321396   Replication of the association of BIN1 with Alzheimer's disease and assessment of genetic interactions.

  21347408   Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers of Alzheimer's disease.

  21358043   PICALM and CR1 variants are not associated with sporadic Alzheimer's disease in Chinese patients.

  21379329   Genome-wide association of late-onset familial Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.

  21390209   Meta-analysis of a genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

  21391232   CR1 is associated with amyloid plaque burden and age-related cognitive decline.

  21459483   Using cerebrospinal fluid biomarkers to replicate genetic associations in Alzheimer's disease.

  21466683   The CLU, CR1 and PICALM genes are associated with senile plaques associated with Alzheimer's disease.

  21547229   Neuroimaging indicators as endophenotypes in Alzheimer's disease.

  21726919   CR1 genotype is associated with entorhinal cortex volume in young healthy adults.

  21766012   Alzheimer's disease genes are associated with rates of cognitive aging in the Lothian cohorts born in 1921 and 1936.

  21912625   An exploratory study on CLU, CR1 and PICALM and Parkinson disease.

  22005930   Genome-wide study of the association of Alzheimer's disease with psychotic symptoms.

  22015308   Polymorphisms of CR1, CLU and PICALM determine susceptibility to Alzheimer's disease in a population of southern China.

  22047634   Alzheimer's Disease Neuroimaging Initiative: A review of articles published since its inception.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22191060   Genetics of late-onset Alzheimer's disease: Alzheimer's database update and common pathway analysis.

  22380508   Cognitive reserve, cortical plasticity, and resistance to Alzheimer's disease.

  22402018   Implication of common and disease specific variants in CLU, CR1, and PICALM.

  22482072   Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.

  22715855   Lack of association of the PICALM rs3851179 polymorphism with Parkinson's disease in the Greek population.

  22833209   Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment.

  22911757   Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

  22943764   Identification and confirmation of an exonic splicing enhancer variation in exon 5 of the Alzheimer disease associated PICALM gene.

  23036585   Exploratory analysis of seven Alzheimer's disease genes: disease progression.

  23040034   Lack of association between the PICALM rs3851179 polymorphism and Alzheimer's disease in the Chinese population and the APOEε4-negative subgroup.

  23180304   Genetic risk assessment predicting accelerated progression from mild cognitive impairment to Alzheimer's disease.

  23429712   A panel of genetic variations as a potential non-invasive biomarker for early diagnosis of Alzheimer's disease.

  23572399   Polymorphism rs3851179 of the PICALM gene contributes to the development of Alzheimer's disease in an Asian population.

  23573206   Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

  24578178   Effects of Alzheimer's disease-associated PICALM and CLU variants on hippocampal functional connectivity in healthy young adults.

  24618820   Genetics of PICALM expression and Alzheimer's disease.

  24643340   Genotype patterns at CLU, CR1, PICALM and APOE, cognition and Mediterranean diet: the PREDIMED-NAVARRA trial.

  24670887   Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.

  24788522   Genome-wide genetic variation at the CELF1 locus (CUGBP, elav-like family member 1 gene) is associated with Alzheimer's disease and obesity.

  25022885   Genetic evidence for the involvement of variants in the APOE, BIN1, CR1 and PICALM loci in the risk of late-onset Alzheimer's disease and assessment of interactions with APOE genotypes.

  25108264   Genomics in neurological disorders.

  25114068   Genetic determinants of progression of Alzheimer's disease.

  25169757   An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform.

  25189118   Risk variants for late-onset Alzheimer's disease include memory loss, mild cognitive impairment, and Alzheimer's disease.

  25359311   Association of MTHFR and PICALM polymorphisms with Alzheimer's disease.

  25452228   Validation of GWAS-identified risk loci for Alzheimer's disease in a Han Chinese population.

  25649863   Identifying genetic interactions associated with late-onset Alzheimer's disease.

  26005850   Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

  26154020   A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia.

  26611835   Meta-analysis of the Association between Alzheimer Disease and Variants in GAB2, PICALM, and SORL1.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26972434   Re: “PICALM rs3851179 gene polymorphism contributes to the development of Alzheimer’s disease in an Asian population.”

  26993346   Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.

  27023435   Association Analysis of Polymorphisms in TOMM40, CR1, PVRL2, SORL1, PICALM, and 14q32.13 Regions in Colombian Alzheimer Disease Patients.

  27048444   The PICALM rs3851179 variant confers susceptibility to Alzheimer's disease in the Chinese population.

  27117083   The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27407070   Obtaining Human Ischemic Stroke Gene Expression Biomarkers from Animal Models: A Cross-species Validation Study.

  27430330   Reduced PICALM expression reduces endocytosis and β-secretase activity: implications for Alzheimer's disease.

  27482534   Alzheimer's disease genetic risk assessment predicts longitudinal thinning of hippocampal subregions in healthy older adults.

  27610127   Analysis of heterogeneous multimodal biomarkers of Alzheimer's disease using a Bayesian network.

  27799753   Mutations associated with early onset Alzheimer's disease have been found in Asian countries.

  28073596   Quantitative EEG in normal aging: association with a genetic risk variant for Alzheimer's disease in the PICALM gene.

  28316001   Associations of Alzheimer's disease candidate gene polymorphisms BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance.

  28549650   Effect of PICALM rs3851179 polymorphism on the default mode network function in mild cognitive impairment.

  28558900   Effect of CLU and PICALM polymorphisms on AD risk: A study from south India.

  29883038   Genetic interactions are associated with lower metabolic connectivity and memory impairment in clinically mild Alzheimer's disease.

  30039188   Correlation of PICALM rs3851179 polymorphism with Alzheimer's disease in Caucasian and Chinese populations: a meta-analysis and systematic review.

  30472946   Genetic association between an Alzheimer's disease risk-associated variant of the PICALM gene and auditory event-related potential in aging.

  30503753   Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls.

  31385771   Association of PICALM gene polymorphisms with Alzheimer's disease: evidence from an updated meta-analysis.

  31648652   rs3851179Gu003eA in PICALM protects against Alzheimer's disease in five Mediterranean countries.

  31971580   Cohort Differences in the Associations of Selected Candidate Genes With Risk of All-Cause Mortality at Advanced Ages.

  32372909   Genetic association between the Alzheimer's disease risk variant of the PICALM gene and EEG functional connectivity in adults without dementia.

  32914893   Association of PICALM with cognitive impairment in Parkinson's disease.

  33170153   Association of Alzheimer's disease risk variants of the PICALM gene with PICALM expression, key biomarkers and features of neurodegeneration.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  33926499   Protective genes and pathways in Alzheimer's disease: Moving toward precision interventions.

  34603005   A Multimodal Risk Network Predicts Executive Function Trajectories in Non-demented Aging.

  34752346   Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls.

  34975449   Structural covariance network as an endophenotype in Alzheimer's disease susceptibility single nucleotide polymorphisms and correlations with cognitive outcomes.

  35222520   Educational Attainment and Ischemic Stroke: A Mendelian Randomization Study.