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SNP information rs3764650

RS3764650

Normal allele: TT

Analysis of large-scale samples confirms an association between the ABCA7 rs3764650 polymorphism and susceptibility to Alzheimer's disease.

Polymorphism rs3764650 is related to topics like this:

Alzheimer's disease is hereditary

Alzheimer's disease is a degenerative brain disease that causes dementia, resulting in a gradual...


Research and publications:

  21460840   Common variants ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

  21460841   Common variants MS4A4/MS4A6E, CD2AP, CD33, and EPHA1 are associated with late-onset Alzheimer's disease.

  22047634   Alzheimer's Disease Neuroimaging Initiative: A review of articles published since its inception.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22403555   A-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration.

  22833209   Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment.

  23180304   Genetic risk assessment predicting accelerated progression from mild cognitive impairment to Alzheimer's disease.

  23669301   Interaction between two cholesterol metabolism genes influences memory: Evidence from the Wisconsin Alzheimer's Disease Registry.

  23836404   Genetic susceptibility for Alzheimer disease neuritic plaque pathology.

  24141082   ABCA7 expression is associated with polymorphisms and Alzheimer's disease status.

  24643655   Analysis of large-scale samples supports an association between the ABCA7 rs3764650 polymorphism and susceptibility to Alzheimer's disease.

  24670887   Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.

  24743338   Connecting the dots: the potential of data integration to identify regulatory SNPs in late-onset Alzheimer's disease GWAS results.

  24908168   ABCA7 gene and risk of Alzheimer's disease among Han Chinese in Taiwan.

  25189118   Risk variants for late-onset Alzheimer's disease include memory loss, mild cognitive impairment, and Alzheimer's disease.

  25426068   Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.

  26141617   Mutations in ABCA7 in a Belgian cohort of patients with Alzheimer's disease: a targeted resequencing study.

  26276146   Characterization of genome-wide H3K27ac profiles reveals a distinct PM2.5-associated histone modification signature.

  26438529   Genetics draws attention to microglial inflammation in Alzheimer's disease.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26795201   Associations Between Genetic Variants in 19p13 and 19q13 Regions and Susceptibility to Alzheimer Disease: A Meta-Analysis.

  26923404   Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy.

  26993346   Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.

  27003212   ABCA7 genotypes increase the risk of Alzheimer's disease by modulating β-amyloid pathology.

  27103528   Association of genetic risk factors with cognitive decline: the PATH through life project.

  27231719   ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.

  27249223   Impact of coding variability in APP-Aβ metabolic genes in sporadic Alzheimer's disease.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27289440   ABCA7 p.G215S as a potential protective factor for Alzheimer's disease.

  27610127   Analysis of heterogeneous multimodal biomarkers of Alzheimer's disease using a Bayesian network.

  28084078   Association of major GWAS genes with late-onset Alzheimer's disease in a Colombian population.

  28477215   Validation of GWAS variants from microglial genes involved in Alzheimer's disease.

  28549481   The genetics of late-onset Alzheimer's disease implicates microglial pathways in disease risk.

  28870582   Association of Alzheimer's disease and type 2 diabetes: new common susceptibility genes discovered by the cFDR approach.

  29111006   Complex relationship between ABCA7 genotypes and blood lipid levels in South Chinese Han patients with sporadic Alzheimer's disease.

  29441941   ATP-binding cassette subfamily A member 7, rs3764650 polymorphism and Alzheimer's disease risk.

  29504051   Updated meta-analysis of BIN1, CR1, MS4A6A, CLU, and ABCA7 variants in Alzheimer's disease.

  29782324   Meta-analysis of the association between ABCA7 variants and Alzheimer's disease.

  30596067   ABCA7 genotype altered cerebrospinal fluid Aβ levels in Alzheimer's disease without dementia.

  31024289   ABCA7 Risk Genotype Diminishes the Neuroprotective Value of Aerobic Fitness in Healthy Older African Americans.

  31469155   Combined risk effect of BIN1, CLU and APOE genes in Alzheimer's disease.

  31659653   ABCA7 and EphA1 gene polymorphism in late-onset Alzheimer's disease.

  31831047   ABCA7 polymorphism correlates with APOEβ4-related memory impairment and default mode network in Alzheimer's disease patients.

  32039842   ABCA7 Genotype Moderates the Effect of Aerobic Exercise Intervention on Generalization of Prior Learning in Healthy Older African Americans.

  32098344   ABCA7-A Member of the ABC Transporter Family in Healthy and Ailing Brain.

  32103964   ABCA7 Gene Expression and Genetic Association Study in Schizophrenia.

  32848603   Impacts of AD-Related ABCA7 and CLU Variants on Default Mode Network Connectivity in Healthy Middle-Age Adults.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  34214049   Association between Alzheimer's disease genes and trajectories of cognitive decline among Han Chinese in Taiwan.

  34975449   Structural covariance network as an endophenotype in Alzheimer's disease susceptibility single nucleotide polymorphisms and correlations with cognitive outcomes.

  35693347   Analysis of the genetic association between ABCA7 polymorphisms and the risk of Alzheimer's disease in a Southern Chinese population.

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