Normal allele: TT
Analysis of large-scale samples confirms an association between the ABCA7 rs3764650 polymorphism and susceptibility to Alzheimer's disease.
Polymorphism rs3764650 is related to topics like this:
Research and publications:
21460840 Common variants ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
22047634 Alzheimer's Disease Neuroimaging Initiative: A review of articles published since its inception.
22159054 A comprehensive genetic association study of Alzheimer disease in African Americans.
22403555 A-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration.
23836404 Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
24141082 ABCA7 expression is associated with polymorphisms and Alzheimer's disease status.
24670887 Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.
24908168 ABCA7 gene and risk of Alzheimer's disease among Han Chinese in Taiwan.
25426068 Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.
26438529 Genetics draws attention to microglial inflammation in Alzheimer's disease.
26680604 Polygenic analysis of late-onset Alzheimer's disease in mainland China.
26923404 Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy.
26993346 Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.
27003212 ABCA7 genotypes increase the risk of Alzheimer's disease by modulating β-amyloid pathology.
27103528 Association of genetic risk factors with cognitive decline: the PATH through life project.
27231719 ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.
27249223 Impact of coding variability in APP-Aβ metabolic genes in sporadic Alzheimer's disease.
27274215 Genes associated with Alzheimer's disease: review and current status.
27289440 ABCA7 p.G215S as a potential protective factor for Alzheimer's disease.
27610127 Analysis of heterogeneous multimodal biomarkers of Alzheimer's disease using a Bayesian network.
28084078 Association of major GWAS genes with late-onset Alzheimer's disease in a Colombian population.
28477215 Validation of GWAS variants from microglial genes involved in Alzheimer's disease.
28549481 The genetics of late-onset Alzheimer's disease implicates microglial pathways in disease risk.
29441941 ATP-binding cassette subfamily A member 7, rs3764650 polymorphism and Alzheimer's disease risk.
29504051 Updated meta-analysis of BIN1, CR1, MS4A6A, CLU, and ABCA7 variants in Alzheimer's disease.
29782324 Meta-analysis of the association between ABCA7 variants and Alzheimer's disease.
30596067 ABCA7 genotype altered cerebrospinal fluid Aβ levels in Alzheimer's disease without dementia.
31469155 Combined risk effect of BIN1, CLU and APOE genes in Alzheimer's disease.
31659653 ABCA7 and EphA1 gene polymorphism in late-onset Alzheimer's disease.
32098344 ABCA7-A Member of the ABC Transporter Family in Healthy and Ailing Brain.
32103964 ABCA7 Gene Expression and Genetic Association Study in Schizophrenia.
33815092 Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.