SNP information rs3213619

Research and publications:

  17146660   Association of MDR1 genotypes with susceptibility to colorectal cancer in older non-smokers.

  17548681   MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia.

  17622943   Comparative and evolutionary pharmacogenetics of ABCB1: complex signatures of positive selection on coding and regulatory regions.

  18424454   ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence.

  20354687   Explaining variability in ciclosporin exposure in adult kidney transplant recipients.

  20389299   Pazopanib-induced hyperbilirubinemia is associated with the UGT1A1 polymorphism of Gilbert's syndrome.

  20628376   Effect of ABCB1 C3435T polymorphism on docetaxel pharmacokinetics according to menopausal status in breast cancer patients.

  21712189   Analysis of pharmacogenetic traits in two distinct South African populations.

  22306099   Association between the functional polymorphism (C3435T) of the gene encoding P-glycoprotein (ABCB1) and major depressive disorder in the Japanese population.

  22723959   Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.

  23050008   Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese population.

  23064017   Donor ABCB1 variant associates with increased risk for kidney allograft failure.

  23319877   Association between ABCB1 Polymorphisms and Ischemic Stroke in Korean Population.

  24116192   Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.

  24122874   Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex.

  24572589   A novel and functional ABCB1 gene variant in sporadic Parkinson's disease.

  24791009   Multidrug resistance 1 gene variants, pesticide exposure, and increased risk of DNA damage.

  24831289   Polymorphisms in ABC transporter genes and concentrations of mercury in newborns--evidence from two Mediterranean birth cohorts.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  26763541   Testing of candidate single nucleotide variants associated with paclitaxel neuropathy in the trial NCCTG N08C1 (Alliance).

  26858644   Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling.

  26870959   Association of PON1, P2Y12 and COX1 with Recurrent Ischemic Events in Patients with Extracranial or Intracranial Stenting.

  27133047   ABCB1 variants confer susceptibility to primary open-angle glaucoma and predict individual differences to latanoprost treatment.

  27175090   The effect of ABCB1 polymorphisms on the outcome of breast cancer treatment.

  29193749   Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  32872162   Pharmacogenomics to Predict Tumor Therapy Response: A Focus on ATP-Binding Cassette Transporters and Cytochromes P450.

  33519226   Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon.

  33709789   Polymorphism of FGD4 and myelosuppression in patients with esophageal squamous cell carcinoma.

  35662334   Association between polymorphisms of ABCB1 and prognosis in esophageal squamous cell carcinoma patients treated with taxane.

  35892315   Pharmacogenetics of taxane-induced neurotoxicity in breast cancer: Systematic review and meta-analysis.