Normal allele: AA
The common variant is associated with increased susceptibility to optic nerve degeneration in glaucoma.
Polymorphism rs284489 is related to topics like this:
Research and publications:
25027321 Genome-wide association and admixture analysis of glaucoma from the Women's Health Initiative.
25171643 Genetics of exfoliation syndrome and glaucoma.
26690118 An Updated Review on the Genetics of Primary Open Angle Glaucoma.
27707548 Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study.
28499933 Major review: Molecular genetics of primary open-angle glaucoma.