Normal allele: AA
Increased risk of islet autoimmunity and type 1 diabetes.
Polymorphism rs2664170 is related to topics like this:
Research and publications:
19430480 Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
20805105 Synthetic associations in the context of genome-wide association scan signals
20885991 Advances and challenges in biomarker development for type 1 diabetes prediction and prevention using omic technologies.
22278338 Confirmation of novel type 1 diabetes risk loci in families.
22315323 Effects of non-HLA gene polymorphisms on development of islet autoimmunity and type 1 diabetes in a population with high-risk HLA-DR,DQ genotypes.
26904692 Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.