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SNP information rs26232


Normal allele: CC

The C5orf30 rs26232 variant is a negative regulator of tissue damage in rheumatoid arthritis and is associated with joint damage in rheumatoid arthritis.

Polymorphism rs26232 is related to topics like this:

Is rheumatoid arthritis genetic

Chronic abnormal inflammation is the hallmark of rheumatoid arthritis, a disease that primarily...

Research and publications:

  20453842   Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

  20510233   Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21120996   Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans.

  21211616   Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.

  21931699   Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset.

  21980439   A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis.

  22294642   Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.

  22328738   Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.

  22661644   Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.

  23121884   Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.

  23817893   Allele-dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis.

  23840476   Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.

  24068971   Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

  24449572   Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

  24968232   Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells.

  26316022   C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis.

  26350950   IL2RA is associated with persistence of rheumatoid arthritis.

  26843965   Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis.

  27214848   Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis.

  27812365   Shared Genetic Etiology of Autoimmune Diseases in Patients from a Biorepository Linked to De-identified Electronic Health Records.

  31652652   Association of the Rheumatoid Arthritis Severity Variant rs26232 with the Invasive Activity of Synovial Fibroblasts.

  32831971   Investigating the GWAS-Implicated Loci for Rheumatoid Arthritis in the Pakistani Population.

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