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SNP information rs2373115

RS2373115

Normal allele: CC

The rs2373115 polymorphism of the GAB2-associated binding protein gene indicates an increased risk (4.1-fold) of late-onset Alzheimer's disease.

Polymorphism rs2373115 is related to topics like this:

Alzheimer's disease is hereditary

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Research and publications:

  17553421   GAB2 alleles alter the risk of Alzheimer's disease in APOE epsilon4 carriers.

  18272374   Study of the association of the GAB2 gene with the risk of developing Alzheimer's disease.

  18854865   GAB2 is not associated with late-onset Alzheimer's disease in Japanese people.

  19118819   The GAB2 gene and risk of Alzheimer's disease: replication and meta-analysis.

  19204163   GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.

  19262956   The GAB2 gene does not alter the risk of Alzheimer's disease in Spanish APOE 4 carriers.

  19276544   Significance of GAB2 gene polymorphism in Italian patients with Alzheimer's disease.

  19924507   GAB2 is not associated with late-onset Alzheimer's disease in Han Chinese.

  20061627   Genome-wide scanning of copy number alterations in late-onset Alzheimer's disease.

  20188796   Association analysis between polymorphism rs2373115 of gene GRB-associated binding protein 2 and Mongolian Alzheimer patients.

  20236449   Genetics of Alzheimer disease in the pre- and post-GWAS era.

  20568290   Identifying genetic interactions in genome-wide data using Bayesian networks.

  20574532   Intermediate phenotypes define different pathways in the development of Alzheimer's disease.

  20594621   Genetic architecture of Alzheimer's disease: beyond APP, PSEN and APOE.

  20634593   Testing the predicted biological effects of SNPs associated with Alzheimer's disease using cerebrospinal fluid biomarker levels.

  20888920   Association between GAB2 haplotype and higher glucose metabolism in Alzheimer's disease brain regions in cognitively normal APOEβ4 carriers.

  21124753   Alzheimer's disease: diagnosis, prognosis and path to prevention.

  21285854   Association study of the GAB2 gene with the risk of Alzheimer disease in the chinese population.

  21480501   Genome-wide replication study of SNPs associated with late-onset Alzheimer's disease.

  21497199   Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects.

  22032181   BioNØT: a searchable database of biomedical negated sentences.

  24161894   The GAB2 rs2373115 polymorphism confers susceptibility to sporadic Alzheimer's disease.

  25649863   Identifying genetic interactions associated with late-onset Alzheimer's disease.

  25853819   GAB2 and BDNF polymorphisms and risk of late-onset Alzheimer's disease in a sample of older adults from Brazil.

  26611835   Meta-analysis of the Association between Alzheimer Disease and Variants in GAB2, PICALM, and SORL1.

  28320126   The GAB2 rs2373115 variant contributes to the risk of Alzheimer's disease, especially in European populations.

  29951493   Impact of GAB2 genetic variations on cerebrospinal fluid markers in Alzheimer's disease.

  30088171   Alzheimer's disease risk variant rs2373115 regulates GAB2 and NARS2 expression in human brain tissue.

  35958936   Association of GAB2 with Quality of Life and Negative Emotions in Patients with Gastric Cancer after Postoperative Comprehensive Care.

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