Normal allele: CC
The rs2373115 polymorphism of the GAB2-associated binding protein gene indicates an increased risk (4.1-fold) of late-onset Alzheimer's disease.
Polymorphism rs2373115 is related to topics like this:
Research and publications:
17553421 GAB2 alleles alter the risk of Alzheimer's disease in APOE epsilon4 carriers.
18272374 Study of the association of the GAB2 gene with the risk of developing Alzheimer's disease.
18854865 GAB2 is not associated with late-onset Alzheimer's disease in Japanese people.
19118819 The GAB2 gene and risk of Alzheimer's disease: replication and meta-analysis.
19204163 GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.
19262956 The GAB2 gene does not alter the risk of Alzheimer's disease in Spanish APOE 4 carriers.
19276544 Significance of GAB2 gene polymorphism in Italian patients with Alzheimer's disease.
19924507 GAB2 is not associated with late-onset Alzheimer's disease in Han Chinese.
20061627 Genome-wide scanning of copy number alterations in late-onset Alzheimer's disease.
20236449 Genetics of Alzheimer disease in the pre- and post-GWAS era.
20568290 Identifying genetic interactions in genome-wide data using Bayesian networks.
20574532 Intermediate phenotypes define different pathways in the development of Alzheimer's disease.
20594621 Genetic architecture of Alzheimer's disease: beyond APP, PSEN and APOE.
21124753 Alzheimer's disease: diagnosis, prognosis and path to prevention.
21285854 Association study of the GAB2 gene with the risk of Alzheimer disease in the chinese population.
21480501 Genome-wide replication study of SNPs associated with late-onset Alzheimer's disease.
22032181 BioNØT: a searchable database of biomedical negated sentences.
24161894 The GAB2 rs2373115 polymorphism confers susceptibility to sporadic Alzheimer's disease.
25649863 Identifying genetic interactions associated with late-onset Alzheimer's disease.
26611835 Meta-analysis of the Association between Alzheimer Disease and Variants in GAB2, PICALM, and SORL1.
29951493 Impact of GAB2 genetic variations on cerebrospinal fluid markers in Alzheimer's disease.