Normal allele: TT
Associated with lower vitamin D levels and therefore potential vitamin D deficiency. Increases vitamin D deficiency among pregnant women and the likelihood of gestational diabetes.
Polymorphism rs2282679 is related to topics like this:
Research and publications:
19255064 Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk
20418485 Genome-wide association study of circulating vitamin D levels.
20541252 Common genetic determinants of vitamin D insufficiency: a genome-wide association study.
21430387 Nutrigenomics, vitamin D and cancer prevention
21431378 Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis.
22112344 Seasonal variation in 25-hydroxyvitamin D concentrations in the cardiovascular health study.
22613962 Genetic influences on vitamin D status and forearm fracture risk in African American children.
22629401 Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.
22673963 Genome-wide association analysis of circulating vitamin D levels in children with asthma.
23319826 Vitamin D and mortality: a Mendelian randomization study.
23793229 Association of common gene variants in vitamin D modulating genes and colon cancer recurrence.
24007655 Genetic variants in vitamin D pathway in Egyptian asthmatic children: a pilot study.
24200978 Serum 25(OH)D and vitamin D status in relation to VDR, GC and CYP2R1 variants in Chinese.
25370324 Vitamin D binding protein gene polymorphism as a risk factor for vitamin D deficiency in Thais.
25533295 Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.
25799011 Vitamin D metabolic pathway genes and pancreatic cancer risk.
26038244 Genetic Variation in CYP2R1 and GC Genes Associated With Vitamin D Deficiency Status.
26141257 Low vitamin D status is associated with more depressive symptoms in Dutch older adults.
26209090 Vitamin D and prostate cancer prognosis: a Mendelian randomization study.
26364161 Meta-analysis of vitamin D-binding protein and cancer risk.
26417870 Potential causal associations between vitamin D and uric acid: Bidirectional mediation analysis.
26446360 Mendelian randomization studies of biomarkers and type 2 diabetes.
26448018 Variants in Vitamin D Binding Protein Gene Are Associated With Gestational Diabetes Mellitus.
26692013 Re-Examining the Association between Vitamin D and Childhood Caries.
27215954 Investigating causality in the association between 25(OH)D and schizophrenia.
27570856 Genetic influence on circulating vitamin D among Saudi Arabians.
27652346 Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk.
27756067 Determinants of Neonatal Vitamin D Levels as Measured on Neonatal Dried Blood Spot Samples.
28161065 Placental genetic variations in vitamin D metabolism and birthweight.
28284354 Vitamin D-binding protein gene polymorphisms are not associated with MS risk in an Italian cohort.
28938476 Fetal and Maternal Genetic Variants Influencing Neonatal Vitamin D Status.
29089348 Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.
29153269 Vitamin D pathway gene polymorphisms influenced vitamin D level among pregnant women.
29220424 Genetically deprived vitamin D exposure predisposes to atrial fibrillation.
29291743 SNPs related to vitamin D and breast cancer risk: a case-control study.
29504805 Vitamin D-binding protein and its polymorphisms as a predictor for metabolic syndrome.
29718335 Negative effect of vitamin D on kidney function: a Mendelian randomization study.
29750416 Serum 25-Hydroxyvitamin D, Plasma Lipids, and Associated Gene Variants in Prepubertal Children.
29892565 The genetic determinants of circulating C3-epimers of 25-hydroxyvitamin D.
29925546 Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study.
31218665 Is there a causal relationship between vitamin D and melanoma risk? A Mendelian randomization study.
31475028 Host Genetic Determinants of Hepatitis B Virus Infection.
32116251 Effect of vitamin D binding protein levels on Alzheimer's disease: a Mendelian randomized trial.
32188599 Genetic Predictors of Circulating 25-Hydroxyvitamin D and Prognosis after Colorectal Cancer.
32593521 Higher levels of 25-hydroxyvitamin D are associated with an increased risk of Bechsche's disease.