SNP information rs2282679

Research and publications:

  19255064   Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk

  20418485   Genome-wide association study of circulating vitamin D levels.

  20541252   Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

  21430387   Nutrigenomics, vitamin D and cancer prevention

  21431378   Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis.

  21441443   Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes

  21828234   Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women

  21853245   The determinants of serum vitamin D levels in participants in a melanoma case-control study living in a temperate climate.

  21972121   Associations between common variants in GC and DHCR7/NADSYN1 and vitamin D concentration in Chinese Hans.

  22112344   Seasonal variation in 25-hydroxyvitamin D concentrations in the cardiovascular health study.

  22144504   Polymorphic variation in the GC and CASR genes and associations with vitamin D metabolite concentration and metachronous colorectal neoplasia.

  22205958   Common variation in vitamin D pathway genes predicts circulating 25-hydroxyvitamin D Levels among African Americans.

  22613962   Genetic influences on vitamin D status and forearm fracture risk in African American children.

  22629401   Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

  22649517   Polymorphisms related to the serum 25-hydroxyvitamin D level and risk of myocardial infarction, diabetes, cancer and mortality. The Tromsø Study.

  22673963   Genome-wide association analysis of circulating vitamin D levels in children with asthma.

  22701574   Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis.

  23191998   Genetic variations in the vitamin D binding protein and season-specific levels of vitamin D among older adults.

  23319826   Vitamin D and mortality: a Mendelian randomization study.

  23456391   Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes.

  23468552   Genetic variants influencing biomarkers of nutrition are not associated with cognitive capability in middle-aged and older adults.

  23505139   An analysis of the association between the vitamin D pathway and serum 25-hydroxyvitamin D levels in a healthy Chinese population.

  23793229   Association of common gene variants in vitamin D modulating genes and colon cancer recurrence.

  24007655   Genetic variants in vitamin D pathway in Egyptian asthmatic children: a pilot study.

  24200978   Serum 25(OH)D and vitamin D status in relation to VDR, GC and CYP2R1 variants in Chinese.

  24219834   An inherited variant in the gene coding for vitamin D-binding protein and survival from cutaneous melanoma: a BioGenoMEL study.

  24516573   Vitamin D levels vary during antiviral treatment but are unable to predict treatment outcome in HCV genotype 1 infected patients.

  24663808   A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness).

  24755831   A novel genetic score approach using instruments to investigate interactions between pathways and environment: application to air pollution.

  24868205   Vitamin D Binding Protein Impact on 25-Hydroxyvitamin D Levels under Different Physiologic and Pathologic Conditions.

  25350643   The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study.

  25370324   Vitamin D binding protein gene polymorphism as a risk factor for vitamin D deficiency in Thais.

  25405862   Vitamin D insufficiency in Arabs and South Asians positively associates with polymorphisms in GC and CYP2R1 genes.

  25533295   Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.

  25738688   Meta-analysis on vitamin D receptor and cancer risk: focus on the role of TaqI, ApaI, and Cdx2 polymorphisms.

  25799011   Vitamin D metabolic pathway genes and pancreatic cancer risk.

  26038244   Genetic Variation in CYP2R1 and GC Genes Associated With Vitamin D Deficiency Status.

  26141257   Low vitamin D status is associated with more depressive symptoms in Dutch older adults.

  26209090   Vitamin D and prostate cancer prognosis: a Mendelian randomization study.

  26275945   Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study.

  26364161   Meta-analysis of vitamin D-binding protein and cancer risk.

  26416604   Vitamin D metabolism-related genetic variants, dietary protein intake and improvement of insulin resistance in a 2 year weight-loss trial: POUNDS Lost.

  26417870   Potential causal associations between vitamin D and uric acid: Bidirectional mediation analysis.

  26446360   Mendelian randomization studies of biomarkers and type 2 diabetes.

  26448018   Variants in Vitamin D Binding Protein Gene Are Associated With Gestational Diabetes Mellitus.

  26546332   Exposure to sub-chronic and long-term particulate air pollution and heart rate variability in an elderly cohort: the Normative Aging Study.

  26692013   Re-Examining the Association between Vitamin D and Childhood Caries.

  26872154   Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants.

  26881316   Independent associations of polymorphisms in vitamin D binding protein (GC) and vitamin D receptor (VDR) genes with obesity and plasma 25OHD3 levels demonstrate sex dimorphism.

  27215954   Investigating causality in the association between 25(OH)D and schizophrenia.

  27570856   Genetic influence on circulating vitamin D among Saudi Arabians.

  27625044   Genetically Low Vitamin D Levels, Bone Mineral Density, and Bone Metabolism Markers: a Mendelian Randomisation Study.

  27652346   Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk.

  27756067   Determinants of Neonatal Vitamin D Levels as Measured on Neonatal Dried Blood Spot Samples.

  27892412   Commentary: Mendelian randomization analysis identifies circulating vitamin D as a causal risk factor for ovarian cancer.

  28161065   Placental genetic variations in vitamin D metabolism and birthweight.

  28278285   Genetic variant in vitamin D-binding protein is associated with metabolic syndrome and lower 25-hydroxyvitamin D levels in polycystic ovary syndrome: A cross-sectional study.

  28284354   Vitamin D-binding protein gene polymorphisms are not associated with MS risk in an Italian cohort.

  28296915   Genetic variation in the vitamin D pathway CYP2R1 gene predicts sustained HBeAg seroconversion in chronic hepatitis B patients treated with pegylated interferon: A multicenter study.

  28415985   Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients.

  28575224   Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants.

  28594127   There is no clear support for a role of vitamin D in Parkinson's disease: a Mendelian randomized trial.

  28834607   Association of baseline vitamin D level with genetic determinants and virologic response in patients with chronic hepatitis B.

  28892641   Independent assortment of GC gene polymorphism (rs2282679) and 25-hydroxyvitamin D levels in coronary artery disease.

  28938476   Fetal and Maternal Genetic Variants Influencing Neonatal Vitamin D Status.

  29089348   Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.

  29153269   Vitamin D pathway gene polymorphisms influenced vitamin D level among pregnant women.

  29220424   Genetically deprived vitamin D exposure predisposes to atrial fibrillation.

  29291743   SNPs related to vitamin D and breast cancer risk: a case-control study.

  29409465   Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake.

  29476721   C3-epimerization of 25-hydroxyvitamin D increases with increasing serum 25-hydroxyvitamin D levels and shows a high degree of tracking over time.

  29504805   Vitamin D-binding protein and its polymorphisms as a predictor for metabolic syndrome.

  29718335   Negative effect of vitamin D on kidney function: a Mendelian randomization study.

  29718904   Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

  29748306   Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study.

  29750416   Serum 25-Hydroxyvitamin D, Plasma Lipids, and Associated Gene Variants in Prepubertal Children.

  29799605   Vitamin D level and risk of systemic lupus erythematosus and rheumatoid arthritis: a Mendelian randomization.

  29892565   The genetic determinants of circulating C3-epimers of 25-hydroxyvitamin D.

  29925546   Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study.

  29937467   Association among genetic variants in the vitamin D pathway and circulating 25-hydroxyvitamin D levels in Korean adults: results from the Korea National Health and Nutrition Examination Survey 2011-2012.

  29993274   The Association Between Vitamin D Binding Protein Polymorphisms and Vitamin D Level on Epilepsy in China.

  30150596   Association between Vitamin D Deficiency and Single Nucleotide Polymorphisms in the Vitamin D Receptor and GC Genes and Analysis of Their Distribution in Mexican Postmenopausal Women.

  30465296   Potential causal associations of serum 25-hydroxyvitamin D with lipids: a Mendelian randomization approach of the HUNT study.

  30475961   Genetically determined vitamin D levels and change in bone density during a weight-loss diet intervention: the Preventing Overweight Using Novel Dietary Strategies (POUNDS Lost) Trial.

  31030503   Vitamin D-Binding protein Gene Polymorphism Predicts Pegylated Interferon-Related HBsAg Seroclearance in HBeAg-Negative Thai Chronic Hepatitis B Patients: A Multicentre Study.

  31218665   Is there a causal relationship between vitamin D and melanoma risk? A Mendelian randomization study.

  31365099   Genetic Variation of the Vitamin D Binding Protein Affects Vitamin D Status and Response to Supplementation in Infants.

  31475028   Host Genetic Determinants of Hepatitis B Virus Infection.

  31640710   DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS naïve HIV-infected patients: a retrospective study.

  31814925   Association of circulating 25-hydroxyvitamin D levels with hypertension and blood pressure values in Korean adults: A Mendelian randomization study on a subset of the Korea National Health and Nutrition Survey 2011-2012 population.

  31830090   Prevalence of vitamin D deficiency in women from southern Brazil and association with vitamin D-binding protein levels and GC-DBP gene polymorphisms.

  31881507   Variants in gene encoding for vitamin D binding protein were associated with leukocyte telomere length: The Pró-Saúde Study.

  32116251   Effect of vitamin D binding protein levels on Alzheimer's disease: a Mendelian randomized trial.

  32188599   Genetic Predictors of Circulating 25-Hydroxyvitamin D and Prognosis after Colorectal Cancer.

  32231377   Genetic predisposition for vitamin D deficiency is not associated with adverse outcome of very low birth weight infants: A cohort study from the German Neonatal Network.

  32289634   Effect of genetic factors on the response to vitamin D(3) supplementation in the VIDARIS randomized controlled trial.

  32517587   Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.

  32537819   Association between variants in vitamin D-binding protein gene and vitamin D deficiency among pregnant women in china.

  32593521   Higher levels of 25-hydroxyvitamin D are associated with an increased risk of Bechsche's disease.