SNP information rs2237892

Research and publications:

  18711367   Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

  18991055   Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.

  19033397   Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.

  19252135   Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.

  19308350   Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population.

  19323962   Genome-wide association studies in type 2 diabetes

  19366866   Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

  19401414   Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population

  19448982   Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China.

  19460916   Genetic architecture of type 2 diabetes: recent progress and clinical implications

  19516902   The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load.

  19526209   Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

  19556355   Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

  19575309   Association study of four variants in KCNQ1 with type 2 diabetes mellitus and premature coronary artery disease in a Chinese population.

  19734549   Ranking of genome-wide association scan signals by different measures

  19741467   Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.

  19750184   Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

  19850681   Association of KCNQ1 polymorphisms with the gestational diabetes mellitus in Korean women.

  19862325   PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population

  20043853   Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus

  20203524   Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk

  20445095   Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency.

  20509872   Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.

  20512086   Variants in KCNQ1, AP3S1, MAN2A1, and ALDH7A1 and the risk of type 2 diabetes in the Chinese Northern Han population: a case-control study and meta-analysis.

  20606385   Polymorphisms in KCNQ1 are associated with gestational diabetes in a Korean population.

  20701788   KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20816152   Obesity and diabetes genetic variants associated with gestational weight gain.

  21091714   The genetics of type 2 diabetes: what have we learned from GWAS?

  21103332   Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies

  21261977   Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US.

  21278902   Genetic risk profiling for prediction of type 2 diabetes

  21289621   Effects of KCNQ1 polymorphisms on the therapeutic efficacy of oral antidiabetic drugs in Chinese patients with type 2 diabetes.

  21368773   Peripheral blood gene expression profiles in metabolic syndrome, coronary artery disease and type 2 diabetes.

  21507254   Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease.

  21573907   Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas.

  21602532   Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.

  21799836   A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.

  21890495   Multi-ethnic studies in complex traits.

  22016621   KCNQ1 haplotypes associate with type 2 diabetes in Malaysian Chinese Subjects.

  22052079   Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.

  22113416   Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study

  22134088   Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis.

  22233651   A genome-wide association study of gestational diabetes mellitus in Korean women

  22237986   Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.

  22364391   The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study.

  22377712   Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

  22377714   Impact of common type 2 diabetes risk gene variants on future type 2 diabetes in the non-diabetic population in Korea.

  22403629   Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp.

  22414228   KCNQ1 gene polymorphisms are associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetic patients.

  22461567   Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1.

  22479571   Several polymorphisms of KCNQ1 gene are associated with plasma lipid levels in general Chinese populations.

  22529894   Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

  22558147   Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes.

  22623978   A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.

  22790062   Association between KCNQ1 genetic variants and obesity in Chinese patients with type 2 diabetes.

  22923468   Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population.

  22971100   Quick, "imputation-free" meta-analysis with proxy-SNPs.

  22972380   Investigation of genetic risk factors for chronic adult diseases for association with preterm birth

  23013243   Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children

  23029294   Meta-analysis of the relationship between common type 2 diabetes risk gene variants with gestational diabetes mellitus

  23073174   From genotype to human β cell phenotype and beyond

  23107108   Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs.

  23133642   The association between KCNQ1 gene polymorphism and type 2 diabetes risk: a meta-analysis.

  23173044   Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.

  23185337   Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.

  23193118   Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium

  23271129   Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes.

  23349771   Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.

  23425704   Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.

  23630301   Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.

  23692438   Association between KCNQ1 genetic variants and QT interval in a Chinese population.

  23786590   Common variants in KCNQ1 confer increased risk of type 2 diabetes and contribute to the diabetic epidemic in East Asians: a replication and meta-analysis.

  24373634   KCNQ1 rs2237892 C→T gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 15,736 patients.

  24861553   Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.

  24864266   Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.

  24926958   Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent.

  24959828   Genetic association study with metabolic syndrome and metabolic-related traits in a cross-sectional sample and a 10-year longitudinal sample of chinese elderly population.

  25127363   Application of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effect.

  25145545   Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?

  25369983   Association between maternal single nucleotide polymorphisms in genes regulating glucose metabolism and risk for neural tube defects in offspring.

  25516658   Case-control study of diabetes-related genetic variants and pancreatic cancer risk in Japan.

  25587982   Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study.

  25658847   Do variants associated with susceptibility to pancreatic cancer and type 2 diabetes reciprocally affect risk?

  25774817   Genetics of type 2 diabetes-pitfalls and possibilities.

  26039078   The rs2237892 Polymorphism in KCNQ1 Influences Gestational Diabetes Mellitus and Glucose Levels: A Case-Control Study and Meta-Analysis.

  26066992   Genetic variants of potassium voltage-gated channel genes (KCNQ1, KCNH2, and KCNE1) affected the risk of atrial fibrillation in elderly patients.

  26240488   Utilizing Genetic Predisposition Score in Predicting Risk of Type 2 Diabetes Mellitus Incidence: A Community-based Cohort Study on Middle-aged Koreans.

  26678516   Variant rs2237892 of KCNQ1 Is Potentially Associated with Hypertension and Macrovascular Complications in Type 2 Diabetes Mellitus in A Chinese Han Population.

  26789123   A HuGE Review and Meta-Analyses of Genetic Associations in New Onset Diabetes after Kidney Transplantation.

  26927145   Polymorphisms in Four Genes (KCNQ1 rs151290, KLF14 rs972283, GCKR rs780094 and MTNR1B rs10830963) and Their Correlation with Type 2 Diabetes Mellitus in Han Chinese in Henan Province, China.

  26930408   Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity.

  26964836   Recent progress in genetic and epigenetic research on type 2 diabetes.

  26970180   KCNQ1 gene variants in the risk for type 2 diabetes and impaired renal function in the Spanish Renastur cohort.

  27053236   Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

  27058589   Transcription Factor 7-Like 2 (TCF7L2) rs7903146 Polymorphism as a Risk Factor for Gestational Diabetes Mellitus: A Meta-Analysis.

  27061195   Studying the Genetics of Complex Disease With Ancestry-Specific Human Phenotype Networks: The Case of Type 2 Diabetes in East Asian Populations.

  27066308   Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study.

  27175665   Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals.

  27310578   Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.