Normal allele: CC
Genetic variability in KCNQ1 is associated with fasting glucose levels and beta-cell function.
Polymorphism rs2237892 is related to topics like this:
Research and publications:
18711367 Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
18991055 Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.
19033397 Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.
19252135 Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.
19308350 Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population.
19323962 Genome-wide association studies in type 2 diabetes
19366866 Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.
19401414 Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
19448982 Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China.
19460916 Genetic architecture of type 2 diabetes: recent progress and clinical implications
19516902 The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load.
19526209 Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
19556355 Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.
19575309 Association study of four variants in KCNQ1 with type 2 diabetes mellitus and premature coronary artery disease in a Chinese population.
19734549 Ranking of genome-wide association scan signals by different measures
19741467 Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.
19750184 Genome-wide association studies for atherosclerotic vascular disease and its risk factors.
19850681 Association of KCNQ1 polymorphisms with the gestational diabetes mellitus in Korean women.
19862325 PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population
20043853 Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus
20203524 Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk
20445095 Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency.
20509872 Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.
20512086 Variants in KCNQ1, AP3S1, MAN2A1, and ALDH7A1 and the risk of type 2 diabetes in the Chinese Northern Han population: a case-control study and meta-analysis.
20606385 Polymorphisms in KCNQ1 are associated with gestational diabetes in a Korean population.
20701788 KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population.
20805105 Synthetic associations in the context of genome-wide association scan signals
20816152 Obesity and diabetes genetic variants associated with gestational weight gain.
21091714 The genetics of type 2 diabetes: what have we learned from GWAS?
21103332 Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies
21261977 Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US.
21278902 Genetic risk profiling for prediction of type 2 diabetes
21289621 Effects of KCNQ1 polymorphisms on the therapeutic efficacy of oral antidiabetic drugs in Chinese patients with type 2 diabetes.
21368773 Peripheral blood gene expression profiles in metabolic syndrome, coronary artery disease and type 2 diabetes.
21507254 Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease.
21573907 Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas.
21602532 Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.
21799836 A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.
21890495 Multi-ethnic studies in complex traits.
22016621 KCNQ1 haplotypes associate with type 2 diabetes in Malaysian Chinese Subjects.
22052079 Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.
22113416 Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study
22134088 Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis.
22233651 A genome-wide association study of gestational diabetes mellitus in Korean women
22237986 Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.
22364391 The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study.
22377712 Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography
22377714 Impact of common type 2 diabetes risk gene variants on future type 2 diabetes in the non-diabetic population in Korea.
22403629 Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp.
22414228 KCNQ1 gene polymorphisms are associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetic patients.
22461567 Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1.
22479571 Several polymorphisms of KCNQ1 gene are associated with plasma lipid levels in general Chinese populations.
22529894 Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.
22558147 Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes.
22623978 A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.
22790062 Association between KCNQ1 genetic variants and obesity in Chinese patients with type 2 diabetes.
22923468 Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population.
22971100 Quick, "imputation-free" meta-analysis with proxy-SNPs.
22972380 Investigation of genetic risk factors for chronic adult diseases for association with preterm birth
23013243 Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children
23029294 Meta-analysis of the relationship between common type 2 diabetes risk gene variants with gestational diabetes mellitus
23073174 From genotype to human β cell phenotype and beyond
23107108 Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs.
23133642 The association between KCNQ1 gene polymorphism and type 2 diabetes risk: a meta-analysis.
23173044 Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.
23185337 Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.
23193118 Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium
23271129 Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes.
23349771 Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.
23425704 Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.
23630301 Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.
23692438 Association between KCNQ1 genetic variants and QT interval in a Chinese population.
23786590 Common variants in KCNQ1 confer increased risk of type 2 diabetes and contribute to the diabetic epidemic in East Asians: a replication and meta-analysis.
24373634 KCNQ1 rs2237892 C→T gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 15,736 patients.
24861553 Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
24864266 Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.
24926958 Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent.
24959828 Genetic association study with metabolic syndrome and metabolic-related traits in a cross-sectional sample and a 10-year longitudinal sample of chinese elderly population.
25127363 Application of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effect.
25145545 Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?
25369983 Association between maternal single nucleotide polymorphisms in genes regulating glucose metabolism and risk for neural tube defects in offspring.
25516658 Case-control study of diabetes-related genetic variants and pancreatic cancer risk in Japan.
25587982 Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study.
25658847 Do variants associated with susceptibility to pancreatic cancer and type 2 diabetes reciprocally affect risk?
25774817 Genetics of type 2 diabetes-pitfalls and possibilities.
26039078 The rs2237892 Polymorphism in KCNQ1 Influences Gestational Diabetes Mellitus and Glucose Levels: A Case-Control Study and Meta-Analysis.
26066992 Genetic variants of potassium voltage-gated channel genes (KCNQ1, KCNH2, and KCNE1) affected the risk of atrial fibrillation in elderly patients.
26240488 Utilizing Genetic Predisposition Score in Predicting Risk of Type 2 Diabetes Mellitus Incidence: A Community-based Cohort Study on Middle-aged Koreans.
26678516 Variant rs2237892 of KCNQ1 Is Potentially Associated with Hypertension and Macrovascular Complications in Type 2 Diabetes Mellitus in A Chinese Han Population.
26789123 A HuGE Review and Meta-Analyses of Genetic Associations in New Onset Diabetes after Kidney Transplantation.
26927145 Polymorphisms in Four Genes (KCNQ1 rs151290, KLF14 rs972283, GCKR rs780094 and MTNR1B rs10830963) and Their Correlation with Type 2 Diabetes Mellitus in Han Chinese in Henan Province, China.
26930408 Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity.
26964836 Recent progress in genetic and epigenetic research on type 2 diabetes.
26970180 KCNQ1 gene variants in the risk for type 2 diabetes and impaired renal function in the Spanish Renastur cohort.
27053236 Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.
27058589 Transcription Factor 7-Like 2 (TCF7L2) rs7903146 Polymorphism as a Risk Factor for Gestational Diabetes Mellitus: A Meta-Analysis.
27061195 Studying the Genetics of Complex Disease With Ancestry-Specific Human Phenotype Networks: The Case of Type 2 Diabetes in East Asian Populations.
27066308 Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study.
27175665 Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals.
27310578 Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.