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SNP information rs2227589

RS2227589

Normal allele: CC

The SERPINC1 rs2227589 prothrombotic polymorphism affects antithrombin levels and risk of deep vein thrombosis.

Polymorphism rs2227589 is related to topics like this:

G20210A prothrombin mutation

The Prothrombin G20210A mutation, also known as Factor II mutation, is a hereditary trait that...


Research and publications:

  18349091   Gene variants associated with deep vein thrombosis.

  19229049   Functional consequences of the prothrombotic SERPINC1 rs2227589 polymorphism on antithrombin levels.

  21072045   A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.

  21232005   New gene variants associated with venous thrombosis: a replication study in White and Black Americans.

  23150947   Single nucleotide polymorphisms and the risk of venous thrombosis: results from a Danish case-cohort study.

  23954867   The association of idiopathic recurrent pregnancy loss with polymorphisms in hemostasis-related genes.

  24226152   Influence of single nucleotide polymorphisms on thrombin generation in factor V Leiden heterozygotes.

  24456740   Apolipoprotein E polymorphism is associated with lower extremity deep venous thrombosis: color-flow Doppler ultrasound evaluation.

  25091233   Association of F11 polymorphism rs2289252 with deep vein thrombosis and related phenotypes in population of Latvia.

  25771983   Polymorphisms in factor V and antithrombin III gene in recurrent pregnancy loss: a case-control study in Indian population.

  27766050   Causes of venous thrombosis.

  28353616   Associations between polymorphisms in coagulation-related genes and venous thromboembolism: A meta-analysis with trial sequential analysis.

  31572449   Association of SERPINC1 Gene Polymorphism (rs2227589) With Pulmonary Embolism Risk in a Chinese Population.

  34979665   Cryptogenic Stroke in the Young: Role of Candidate Gene Polymorphisms in Indian Patients with Ischemic Etiology.

  35097087   Patients with SERPINC1 rs2227589 polymorphism found to have multiple cerebral venous sinus thromboses despite a normal antithrombin level: A case report.

  20031567   Assessing candidate inflammatory and thrombotic genes for venous thromboembolism risk: the Women's Genome Health Study.

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