SNP information rs2069762

Research and publications:

  16333313   Family based association analysis of the IL2 and IL15 genes in allergic disorders.

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  17152005   Associations between measles vaccine immunity and single-nucleotide polymorphisms in cytokine and cytokine receptor genes.

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17355643   Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population

  18598732   Vaccine immunogenetics: bedside to bench to population.

  18628433   Cervical and vulvar cancer risk in relation to the joint effects of cigarette smoking and genetic variation in interleukin 2.

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  19058298   Promoter polymorphisms of IL2, IL4, and risk of gastric cancer in a high-risk Chinese population.

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19126646   Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of USA

  19147066   Genomic and proteomic analysis of allogeneic hematopoietic cell transplant outcome. Seeking greater understanding the pathogenesis of GVHD and mortality

  19173720   Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants.

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19450131   Application of pharmacogenomics to vaccines

  19523143   Multiple sclerosis association study with the TENR-IL2-IL21 region in a Spanish population.

  19773451   Role of inflammation gene polymorphisms on pain severity in lung cancer patients

  20184734   The 4q27 locus and prostate cancer risk.

  20406895   Genetic variants in inflammation pathway genes and asthma in glioma susceptibility

  20418110   Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer

  20452482   Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

  20673868   A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

  20811626   Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer

  20827186   Defining genetic risk for graft-versus-host disease and mortality following allogeneic hematopoietic stem cell transplantation

  20952689   Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma

  21160888   Genetic predisposition to Helicobacter pylori-induced gastric precancerous conditions

  21362111   A case-control study reveals immunoregulatory gene haplotypes that influence inhibitor risk in severe haemophilia A.

  21467728   Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

  21621256   Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations.

  21648020   Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese.

  21649724   Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country.

  21658613   Host genetics in follicular lymphoma.

  21829393   Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

  21873553   Genetic analysis of adult-onset autoimmune diabetes.

  21875636   Associations between single nucleotide polymorphisms and haplotypes in cytokine and cytokine receptor genes and immunity to measles vaccination.

  21919968   Validation of genetic variants associated with early acute rejection in kidney allograft transplantation.

  21955043   Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi-center cohort.

  22059093   Risk Factors of Non-Hodgkin Lymphoma.

  22113576   Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.

  22180854   Polymorphisms in Th1/Th2 cytokine genes, hormone replacement therapy, and risk of non-Hodgkin lymphoma.

  22230215   Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study.

  22241978   Vaccinomics and personalized vaccinology: is science leading us toward a new path of directed vaccine development and discovery?

  22377791   Association of genetic polymorphisms of interleukins with new-onset diabetes after transplantation in renal transplantation.

  22479496   Compensatory T-cell regulation in unaffected relatives of SLE patients, and opposite IL-2/CD25-mediated effects suggested by coreferentiality modeling.

  22674296   Interleukin genes and associations with colon and rectal cancer risk and overall survival.

  22754588   Risk Factors of Follicular Lymphoma.

  23172754   Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility.

  23217119   In-vitro characterization of novel and functional regulatory SNPs in the promoter region of IL2 and IL2R alpha in a Gabonese population.

  23406059   Inflammatory factors gene polymorphism in recurrent oral ulceration.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24154763   Polymorphic variant at the IL2 region is associated with type 1 diabetes and may affect serum levels of interleukin-2.

  24176007   Potential association of pulmonary tuberculosis with genetic polymorphisms of toll-like receptor 9 and interferon-gamma in a Chinese population.

  24281113   Inflammatory genetic markers of prostate cancer risk.

  24309190   Genetics of new-onset diabetes after transplantation.

  24367383   Evidence of stage- and age-related heterogeneity of non-HLA SNPs and risk of islet autoimmunity and type 1 diabetes: the diabetes autoimmunity study in the young.

  24392269   Gene-Lifestyle Interactions in Obesity.

  24903211   The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.

  25037274   Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population.

  25075970   The associations between immunity-related genes and breast cancer prognosis in Korean women.

  25214541   A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.

  25238536   Association of cytokines in individuals sensitive and insensitive to dust mites in a Brazilian population.

  25294155   A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.

  25347332   Interleukin-2 and its soluble receptor alpha subunit in autoimmune Addison's disease—an association study and expression analysis.

  25495849   4q27 as a psoriasis susceptibility locus in the Northeastern Chinese Han population.

  25962811   Non-Hodgkin Lymphoma, Body Mass Index, and Cytokine Polymorphisms: A Pooled Analysis from the InterLymph Consortium.

  26106387   Pathogenesis of Systemic Sclerosis.

  26229483   IL-2 -330T/G polymorphism and cancer risk: a meta-analysis.

  26771888   Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial.

  26840977   Single Nucleotide Polymorphisms in IL17A and IL6 Are Associated with Decreased Risk for Pulmonary Tuberculosis in Southern Brazilian Population.

  27051588   Analysis of single nucleotide polymorphisms implicate mTOR signalling in the development of new-onset diabetes after transplantation.

  27419029   Influence of cigarette smoking and inflammatory gene polymorphisms on glycated hemoglobin in the Japanese general population.

  27570418   Hepatitis-related hepatocellular carcinoma: Insights into cytokine gene polymorphisms.

  28111424   Effects of Soy Product Intake and Interleukin Genetic Polymorphisms on Early Gastric Cancer Risk in Korea: A Case-Control Study.

  28159384   Single nucleotide polymorphisms of IL-2, but not IL-12 and IFN-γ, are associated with increased susceptibility to chronic spontaneous urticaria.

  28374494   Immunogenetic profiling of 23 SNPs of cytokine and chemokine receptor genes through a minisequencing technique: Design, development and validation.

  28458166   Polymorphisms and haplotypes of the interleukin 2 gene are associated with an increased risk of gastric cancer. The possible involvement of Helicobacter pylori.

  28765340   Lack of Association for Reported Endocrine Pancreatic Cancer Risk Loci in the PANDoRA Consortium.

  28838891   Interaction effects among IFN-γ+874, IL-2-330, IL-10-1082, IL-10-592 and IL-4-589 polymorphisms on the clinical progression of subjects infected with hepatitis B virus and/or hepatitis C virus: a retrospective nested case-control study.

  29288086   Autoimmune hepatitis association with single nucleotide polymorphism of interleukin-2, but not interferon-gamma.

  29993342   Polymorphisms in the TGF-β1 (rs1982037) and IL-2 (rs2069762, rs4833248) genes are not associated with inhibitor development in Iranian patients with hemophilia A.

  30203425   Study of gene polymorphisms as predictors of treatment efficacy and toxicity in patients with indolent non-hodgkin lymphomas and mantle cell lymphoma receiving bendamustine and rituximab.

  30212785   IFNG +874 A/T is associated with acute lymphoblastic leukemia in Mexican Mestizos.

  30341786   Recurrent aphthous stomatitis and gene variability in selected interleukins: a case-control study.

  30392849   Antiretroviral therapy immunologic non-response in a Brazilian population: association study using pharmaco- and immunogenetic markers.

  30729267   IL-2 gene polymorphisms affect tacrolimus response in myasthenia gravis.

  30939298   Interleukin gene polymorphisms in chronic periodontitis: A case-control study in the Indian population.

  30959967   Genetic Susceptibility in Head and Neck Squamous Cell Carcinoma in a Spanish Population.

  31393896   Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania (V.) guyanensis in Manaus, Amazonas, Brazil.

  31519598   Genetic Variants of the IL2 Gene Related to Risk and Survival in Patients With Colorectal Cancer.

  31669382   Associations of polymorphisms in interleukins with tuberculosis: Evidence from a meta-analysis.

  32124188   Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study.

  32425678   Polymorphisms of genes encoding cytokines predict the risk of high-grade bladder cancer and outcomes of BCG immunotherapy.

  32432788   Effects of gene polymorphism and serum levels of IL-2 and IL-6 on endometriosis.

  33648463   Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma.

  33682577   The Association between IL2 Genotypes and Risk and Severity of Chronic Periodontitis in a Chinese Han Population: A Case-control Study.

  33721333   Cytokine gene polymorphisms are associated with response to blinatumomab in B-cell acute lymphoblastic leukemia.

  34018329   Association of single-nucleotide polymorphisms in tumour necrosis factor and human leukocyte antigens genes with type 1 diabetes.

  34744338   The Influence of Interleukin-2 Gene Polymorphisms on the Risk and Clinical Outcome of Non-Hodgkin Lymphoma.