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SNP information rs20541


Normal allele: GG

Polymorphism rs20541 is related to topics like this:

Is asthma hereditary

Asthma is a respiratory condition that involves inflammation of the airways and recurring episodes...

Leukemia is it genetic

Acute myeloid leukemia (AML) is a diverse cancer that primarily impacts individuals aged 60 and...

Research and publications:

  10699178   Genetic variants of IL-13 signalling and human asthma and atopy.

  12928861   A common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis.

  15356556   Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants.

  15483090   Polymorphism of the interleukin-13 gene determines the susceptibility of the Japanese population to Graves' disease.

  15660293   No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.

  15711639   IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation.

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  16024651   Polymorphisms associated with asthma are inversely related to glioblastoma multiforme.

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  16702372   Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity.

  16759385   Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)

  16832637   Evaluation of interleukin 13 polymorphisms in systemic sclerosis.

  17135570   Localization of a long-range cis-regulatory element of IL13 by allelic transcript ratio mapping.

  17303794   Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17346294   IL13 gene polymorphism association with cord serum immunoglobulin E.

  17561245   Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.

  17615386   IL13 promoter polymorphism 1112C/T modulates the adverse effect of tobacco smoking on lung function.

  17705862   Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples

  18006935   An international case-control study of interleukin-4Ralpha, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk.

  18056382   Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.

  18075513   Variants in the 5q31 cytokine gene cluster are associated with psoriasis.

  18186920   IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study.

  18410415   Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood.

  18417506   Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts: the allergenic study.

  18614543   The 5q31 variants associated with psoriasis and Crohn's disease are different.

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18676870   Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China

  18687755   Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population

  18778477   Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival.

  18846228   Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19169254   Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.

  19254294   Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort.

  19262574   Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19533685   Common genetic variants and risk for non-Hodgkin lymphoma and adult T-cell lymphoma/leukemia in Jamaica.

  19554022   Association between IL13 polymorphisms and psoriatic arthritis is modified by smoking.

  19578876   The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.

  19706623   An allergy-associated polymorphism in a novel regulatory element enhances IL13 expression.

  19759553   Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort.

  19773451   Role of inflammation gene polymorphisms on pain severity in lung cancer patients

  19796199   Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease.

  19840389   Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria.

  19956101   Overview of the Rapid Response data

  19956102   Evidence for association of the TCF7 locus with type I diabetes.

  19956106   Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.

  19956109   Type I Diabetes Genetics Consortium Rapid Response Family-Based Candidate Gene Study: Strategy, Gene Selection, and Key Findings.

  20015396   Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.

  20112337   Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers

  20159242   Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.

  20211558   Genetic advances in glioma: susceptibility genes and networks.

  20298583   Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma.

  20332709   Analysis of the association of IL-3, IL-4, IL-5, IL-9 and IL-13 polymorphisms with Graves' disease.

  20358028   IL-13 Gene Polymorphisms are Associated With Rhinosinusitis and Eosinophilic Inflammation in Aspirin Intolerant Asthma.

  20403202   Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study.

  20406895   Genetic variants in inflammation pathway genes and asthma in glioma susceptibility

  20417488   Association of fetal inflammation and coagulation pathway gene polymorphisms with neurodevelopmental delay at age 2 years

  20418110   Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer

  20484924   Interleukin 13 and interleukin 4 receptor-α polymorphisms in rhinitis and asthma.

  20606885   Genetics of psoriasis and psoriatic arthritis.

  20662065   Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.

  20811626   Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer

  20860503   A large-scale, consortium-based genomewide association study of asthma.

  20885906   Unraveling the genetic basis of asthma and allergic diseases.

  20952689   Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma

  20953190   A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

  20975284   Case-control study of eczema associated with IL13 genetic polymorphisms in Japanese children.

  21050946   Does genetic regulation of IgE begin in utero? Evidence from T(H)1/T(H)2 gene polymorphisms and cord blood total IgE.

  21103062   Unifying candidate gene and GWAS Approaches in Asthma.

  21246217   BR-squared: a practical solution to the winner's curse problem in genome-wide scanning.

  21253569   Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?

  21309855   A meta-analysis of Th2 pathway genetic variants and risk for allergic rhinitis.

  21315679   Green tea consumption, inflammation and the risk of primary hepatocellular carcinoma in a Chinese population

  21320344   Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.

  21324477   Genetic biomarkers of health-related quality of life in pediatric asthma.

  21333900   The role of genetics in IBS

  21349879   Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris.

  21559375   A genetic risk score combining ten psoriasis risk loci improves disease prediction.

  21613309   IL13 gene polymorphism is a marker for psoriatic arthritis among psoriasis patients.

  21659657   The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility.

  21708280   Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis

  21857939   Associations of IL-4, IL-4R and IL-13 gene polymorphisms in pneumoconiosis of coal industry workers in China: a case-control study.

  21858135   Efficient replication of over 180 genetic associations with self-reported medical data.

  21867552   Host candidate gene polymorphisms and clearance of drug-resistant Plasmodium falciparum parasites.

  21913997   Association of polymorphisms in genes encoding IL-4, IL-13 and their receptors with atopic dermatitis in a Korean population.

  21995669   A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS.

  22045834   Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression.

  22075330   A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.

  22087298   Association study on IL4, IL13 and IL4RA polymorphisms in mite-sensitized persistent allergic rhinitis in a Chinese population.

  22113576   Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.

  22180854   Polymorphisms in Th1/Th2 cytokine genes, hormone replacement therapy, and risk of non-Hodgkin lymphoma.

  22197932   Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

  22201026   Genome-wide pathway analysis to study the association of psoriasis and Behçet's disease.

  22222605   IL-13 polymorphisms contribute to the risk of asthma: a meta-analysis.

  22272211   Different implications of paternal and maternal atopy for perinatal IgE production and asthma development.

  22286212   Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.

  22355322   Gene-gene and gene-environmental interactions of childhood asthma: a multifactor dimension reduction approach.

  22357570   The Peru Urban versus Rural Asthma (PURA) Study: methods and baseline quality control data from a cross-sectional investigation into the prevalence, severity, genetics, immunology and environmental factors affecting asthma in adolescence in Peru

  22376040   Gene-gene interactions between candidate gene polymorphisms are associated with total IgE levels in Korean children with asthma.

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