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SNP information rs2040410

Normal allele: GG

One of two polymorphisms (rs2040410 and rs7454108) that determine the highest risk of type 1 diabetes.

Polymorphism rs2040410 is related to topics like this:

Type 1 diabetes


Research and publications:

  18694972   Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening.

  19116921   Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region.

  19143810   Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype.

  19143815   MHC fine mapping of human type 1 diabetes using the T1DGC data.

  19387463   Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC.

  21533074   GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.

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