SNP information rs1946518

Research and publications:

  15896202   Interleukin-18-promoter polymorphisms are not relevant in rheumatoid arthritis.

  16078996   Association study of functional genetic variants of innate immunity related genes in celiac disease.

  16443795   Analysis of polymorphisms of the interleukin-18 gene in type 1 diabetes and Hardy-Weinberg equilibrium testing.

  16542373   Interleukin 18 and human immunodeficiency virus type I infection in adolescents and adults.

  16909454   NeuroD1 gene and interleukin-18 gene polymorphisms in type 1 diabetes in Dalmatian population of Southern Croatia.

  17705862   Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples

  17854431   Interleukin-18 gene polymorphisms and haplotypes in patients with oral lichen planus: a study in an ethnic Chinese cohort.

  17919265   Polymorphism of interleukin-18 promoter influences the onset of kidney graft function after transplantation.

  18043444   Interleukin (IL)-18 polymorphism 133C/G is associated with severe respiratory syncytial virus infection.

  18307517   Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans

  18504197   [Correlation of serum IL-18 level and IL-18 gene promoter polymorphisms to the risk of cervical cancer].

  19073159   Interleukin-18 promoter polymorphism and risk of late-onset Alzheimer's disease.

  19178691   Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery.

  19229765   Interleukin-18 gene (IL18) promoter polymorphisms in patients with rheumatoid arthritis.

  19455410   Interleukin 18 promoter variants (-137G>C and -607C>A) in patients with chronic hepatitis C: association with treatment response.

  19961892   Impact of interleukin-18 polymorphisms-607 and -137 on clinical characteristics of renal cell carcinoma patients.

  20097272   Interleukin-18 promoter polymorphisms and risk of ischemic stroke.

  20304021   Haplotype analysis of the interleukin-18 gene in Czech patients with allergic disorders.

  20331879   Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis.

  20416077   Identification of type 2 diabetes-associated combination of SNPs using support vector machine.

  20478055   Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study.

  21149337   Dense mapping of IL18 shows no association in SLE.

  21160409   Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population

  21225442   Interleukin-18 promoter polymorphisms in Japanese patients with rheumatoid arthritis: protective effect of the T allele and T/T genotype at rs360722.

  21241672   Interleukin-18 promoter polymorphism and risk of Parkinson's disease in a Chinese Han population.

  21395662   Relationship between single nucleotide polymorphism of interleukin-18 and susceptibility to pulmonary tuberculosis in the Chinese Han population.

  21470492   Interleukin-18 promoter polymorphisms in patients with systemic lupus erythematosus.

  21532063   IL18 polymorphism is associated with Behçet's disease but not with lupus in Turkish patients.

  21611751   Interleukin-18 promoter polymorphism and asthma risk: a meta-analysis.

  21742843   Common SNPs/haplotypes in IL18R1 and IL18 genes are associated with variations in humoral immunity to smallpox vaccination in Caucasians and African Americans.

  21775533   Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.

  21962565   Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events.

  21969001   Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.

  21984735   High plasma interleukin-18 levels mark the acute phase of hepatitis C virus infection.

  22008665   The associations of IL-18 serum levels and promoter polymorphism with tacrolimus pharmacokinetics and hepatic allograft dysfunction in Chinese liver transplantation recipients.

  22136483   Evaluation of IL18 and IL18R1 polymorphisms: genetic susceptibility to knee osteoarthritis.

  22141572   Circulating levels of IL-18 are significantly influenced by the IL-18 +183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an observational study.

  22300735   Genetic predisposition factors and nasopharyngeal carcinoma risk: a review of epidemiological association studies, 2000-2011: Rosetta Stone for NPC: genetics, viral infection, and other environmental factors.

  22325058   Association of polymorphisms in interleukin-18 and interleukin-28B with hepatitis B recurrence after liver transplantation in Chinese Han population

  22649680   Association of cytokine gene alleles with the inflammation of human periodontal tissue.

  22664470   Interleukin-18 pathway genes are associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma.

  23073298   The IL18 gene and Hashimoto thyroiditis in children.

  23153245   Association of IL-18 polymorphisms with rheumatoid arthritis and systemic lupus erythematosus in Asian populations: a meta-analysis.

  23238919   Association between interleukin-18 polymorphisms and systemic lupus erythematosus: a meta-analysis.

  23302036   Gender-specific association of the interleukin 18 gene with symptomatic gallstone disease.

  23557801   Interleukin 18 (IL18) gene promoter polymorphisms are associated with type 1 diabetes mellitus in Brazilian patients.

  23587914   Interleukin-18 gene polymorphisms and rheumatoid arthritis: a meta-analysis.

  24176007   Potential association of pulmonary tuberculosis with genetic polymorphisms of toll-like receptor 9 and interferon-gamma in a Chinese population.

  24281113   Inflammatory genetic markers of prostate cancer risk.

  24349532   Impact of interleukin-18 polymorphisms -607A/C and -137G/C on oral cancer occurrence and clinical progression.

  24621393   Genetic polymorphisms in the IL-18 gene and ulcerative colitis risk: a meta-analysis.

  24898701   Functional polymorphisms of interleukin-18 gene and risk of breast cancer in a Brazilian population.

  24969483   IL-18 genetic polymorphisms may contribute to the pathogenesis of tuberculosis among Asians: a meta-analysis of case-control studies.

  24976707   Human genes involved in hepatitis B virus infection.

  25061809   Analyzing genome-wide association studies with an FDR controlling modification of the Bayesian Information Criterion.

  25192895   Association of IL-18 promoter gene polymorphisms with rheumatoid arthritis: a meta-analysis.

  25374428   Interleukin-18 gene promoter polymorphisms and celiac disease in Italian patients.

  25487141   Association between interleukin-18 promoter variants and tacrolimus pharmacokinetics in Chinese renal transplant patients.

  25690033   Genetic variant in interleukin-18 is associated with idiopathic recurrent miscarriage in Chinese Han population.

  25712187   Donor IL-18 rs5744247 polymorphism as a new biomarker of tacrolimus elimination in Chinese liver transplant patients during the early post-transplantation period: results from two cohort studies.

  26026656   Ethnicity-stratified analysis of the association between IL-18 polymorphisms and systemic lupus erythematosus in a European population: a meta-analysis.

  26041375   A gene-disease association study of IL18 in thyroid cancer: genotype and haplotype analyses.

  26042207   Association between interleukin-18 gene promoter (- 607C/A and - 137G/C) polymorphisms and chronic hepatitis C virus infections: A meta-analysis.

  26096341   Association between interleukin-18 gene polymorphism and Helicobacter pylori infection in the Korean population.

  26116895   Interleukin-18 promoter -607 C/A and -137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis.

  26213495   Association between IL-18 polymorphisms, serum levels, and HBV-related hepatocellular carcinoma in a Chinese population: a retrospective case-control study.

  26229413   Genetic polymorphisms of interleukin-18 have different effects on susceptibility to Crohn's disease.

  26445852   Genetic biomarkers of susceptibility and progression of Barrett's esophagus to dysplasia and cancer: a systematic review and meta-analysis.

  26486291   ANALYSIS OF POLYMORPHISMS IN THE INTERLEUKIN 18 GENE PROMOTOR (-137 G/C AND -607 C/A) IN PATIENTS INFECTED WITH HEPATITIS C VIRUS FROM THE BRAZILIAN AMAZON.

  26690141   IL-18 and Cutaneous Inflammatory Diseases.

  26698117   Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort.

  26800664   Association of cytokine gene polymorphisms (IL-6, IL-12B, IL-18) with Behçet's disease: a meta-analysis.

  26830320   Lack of association between IL-10 and IL-18 gene promoter polymorphisms and Parkinson's disease with cognitive impairment in a Chinese population.

  27027876   IL18 Gene Variants Influence the Susceptibility to Chagas Disease.

  27028244   Interleukin 18 -607 A/C Gene Polymorphism is Associated With Susceptibility to IgA Nephropathy in a Chinese Han Population.

  27054030   Dual roles of cytokines in Alzheimer's disease: update on interleukins, TNF-α, TGF-β, and IFN-β.

  27098064   Association of interleukin-1 family cytokines single nucleotide polymorphisms with susceptibility to systemic sclerosis: an independent case-control study and a meta-analysis.

  27352267   Interleukin-10.rs1800896 and Interleukin-18.rs1946518 gene polymorphisms could not predict the outcome of hepatitis C virus infection in Egyptian patients treated with pegylated interferon plus ribavirin.

  27419078   Interleukin-18 gene promoter 607A polymorphism, but not 137C polymorphism, is a protective factor for ischemic stroke in the Chinese population: A meta-analysis.

  27430614   A Functional Interleukin-18 Haplotype Predicts Depression and Anxiety through Increased Threat-Related Amygdala Reactivity in Women but Not Men.

  27483258   Molecular Mechanisms of Cutaneous Inflammatory Disorder: Atopic Dermatitis.

  27536357   Genetic predisposition to Barrett's esophagus: lessons from early research.

  27703550   Serum Interleukin-18 and Its Gene Haplotypes Profile as Predictors in Patients with Diabetic Nephropathy.

  27775096   Genetic analysis of innate immunity in Behçet's disease reveals an association with IL-37 and IL-18RAP.

  27928589   Genetic polymorphisms of IL-18 rs1946518 and IL-1β rs16944 are associated with prognosis and survival of acute myeloid leukemia.

  28000712   Genetic polymorphisms -137 (rs187238) and -607 (rs1946518) in the interleukin-18 promoter may not be associated with development of hepatocellular carcinoma.

  28139755   Genetically determined high activity of IL-12 and IL-18 in ulcerative colitis and TLR5 in Crohns disease were associated with non-response to anti-TNF therapy.

  28246425   Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients.

  28580570   IL16 and IL18 gene polymorphisms in women with gestational diabetes.

  28692122   Alteration of -656(G/T) and -607(C/A) polymorphisms in interleukin-18 (IL-18) gene in house dust mite-sensitive allergic rhinitis patients in Thailand.

  28834572   Multiple genetic variants associated with posttransplantation diabetes mellitus in Chinese Han populations.

  29061223   Association between donor and recipient Interleukin-18 gene polymorphisms and the risk of infection after liver transplantation.

  29097263   The genetic polymorphism and expression profiles of NLRP3 inflammasome in patients with chronic myeloid leukemia.

  29129846   The IL18 Promoter Polymorphism, rs1946518, Is Associated with the Risk of Periodontitis in Japanese Women: The Kyushu Okinawa Maternal and Child Health Study.

  29136357   Association of cytokine gene polymorphisms with bronchopulmonary dysplasia in Han Chinese newborns.

  29312552   NLRP3 inflammasome activation plays a carcinogenic role through effector cytokine IL-18 in lymphoma.

  29349811   Genetic analysis of interleukin 18 gene polymorphisms in alopecia areata.

  29403300   Association between IL-18/18R gene polymorphisms and coronary artery disease: influence of IL-18/18R genetic variants on cytokine expression.

  29743792   Effect of Sofosbuvir Plus Daclatasvir in Hepatitis C Virus Genotype-4 Patients: Promising Effect on Liver Fibrosis.

  30059753   Association of IL18 genetic polymorphisms with increased risk of Biliary atresia susceptibility in Southern Chinese children.