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SNP information rs1878406

RS1878406

Normal allele: CC

The rs1878406 polymorphism of the endothelin receptor gene is associated with severe multivessel coronary artery disease.

Polymorphism rs1878406 is related to topics like this:

Genetics and atherosclerosis

Atherosclerosis is a progressive inflammatory disorder that underlies coronary artery disease (CAD)...

Research and publications:

  21909108   Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

  24219970   Common genetic variants do not associate with CAD in familial hypercholesterolemia.

  24932356   Genetics of coronary artery disease: an update.

  25542012   Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

  26520901   Impact of carotid atherosclerosis loci on cardiovascular events.

  26847647   Experimental Biology for the Identification of Causal Pathways in Atherosclerosis.

  26892960   From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  27189168   The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.

  28209224   Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

  28426714   A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death.

  28686695   Coronary artery disease-associated genetic variants and biomarkers of inflammation.

  28777867   [Association of endotheline receptor gene rs1878406 polymorphism with severe multi-vessel coronary disease].

  29695241   Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

  31845553   Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses.

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