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SNP information rs17388568

RS17388568

Normal allele: GG

Genetic predisposition to insulin-dependent type 1 diabetes.

Polymorphism rs17388568 is related to topics like this:

Type 1 diabetes is it genetic

Our latest inclusion in the health report is the Type 1 Diabetes Genetic Risk Score, aimed at...


Research and publications:

  17554260   Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

  18369459   A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.

  19140132   Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.

  19201773   Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.

  19359276   Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  20088021   Screen and clean: a tool for identifying interactions in genome-wide association studies.

  20179739   Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.

  20184734   The 4q27 locus and prostate cancer risk.

  20203524   Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk

  20549515   Genome-wide searching of rare genetic variants in WTCCC data.

  20553587   Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.

  20722033   The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  21036813   A variable selection method for genome-wide association studies.

  21297633   Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

  21425124   Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.

  21765104   Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.

  21875375   Study of polymorphisms in 4q27, 10p15, and 22q13 regions in autoantibodies stratified type 1 diabetes patients.

  22496761   Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis.

  22654555   Genetic basis of Graves' disease.

  23817569   A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.

  26214689   Genetic Loci Associated with Allergic Sensitization in Lithuanians.

  27153677   Assessing statistical significance in multivariable genome wide association analysis.

  27892471   Combining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies.

  30888520   Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.

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