SNP information rs16892766

Research and publications:

  18372905   A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

  19010329   Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome.

  19011631   Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

  19786869   Recent insights into the pathogenesis of colorectal cancer.

  19843678   Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.

  20501757   Low-penetrance susceptibility variants in familial colorectal cancer.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20585100   Genome-wide association studies of cancer.

  20628028   Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis.

  20638935   Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype.

  20648012   Association studies on 11 published colorectal cancer risk loci.

  20659471   Genetic heterogeneity in colorectal cancer associations between African and European americans.

  20862326   Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

  20932292   Genome profiling of ERBB2-amplified breast cancers.

  21071539   Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.

  21088407   Chronic inflammation, colorectal cancer and gene polymorphisms.

  21097774   Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome.

  21119214   Colorectal cancer susceptibility loci in a population-based study: Associations with morphological parameters.

  21219822   [Recent progress in genetic variants associated with cancer and their implications in diagnostics development].

  21314996   Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci.

  21357381   Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study.

  21407259   Evaluation of Lynch syndrome modifier genes in 748 MMR mutation carriers.

  21531788   Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes.

  21761138   Meta-analysis of new genome-wide association studies of colorectal cancer risk.

  22045029   Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.

  22235025   Susceptibility genetic variants associated with early-onset colorectal cancer.

  22363440   cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

  22367214   Characterization of gene-environment interactions for colorectal cancer susceptibility loci.

  22532847   Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population.

  22629442   Evaluation of allele-specific somatic changes of genome-wide association study susceptibility alleles in human colorectal cancers.

  22675446   Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.

  22848671   Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

  22879968   Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.

  22987364   Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers.

  22999960   Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

  23300701   Genome-wide search for gene-gene interactions in colorectal cancer.

  23350875   A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.

  23434150   Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  24587672   New genes emerging for colorectal cancer predisposition.

  24705330   Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery.

  24743840   Genome-wide diet-gene interaction analyses for risk of colorectal cancer.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  24801760   Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.

  24978480   A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis.

  25293934   Quantitative assessment of the influence of common variation rs16892766 at 8q23.3 with colorectal adenoma and cancer susceptibility.

  25873010   Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk.

  25963333   A subset of genetic susceptibility variants for colorectal cancer also has prognostic value.

  26880076   Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers.

  26940994   GWASeq: targeted re-sequencing follow up to GWAS.

  27078840   Genetic Variants Associated with Colorectal Adenoma Susceptibility.

  27079684   Genome-wide association studies and epigenome-wide association studies go together in cancer control.

  27145994   Common genetic variation in ETV6 is associated with colorectal cancer susceptibility.

  27146020   Colorectal cancer risk genes are functionally enriched in regulatory pathways.

  27379672   Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.

  28084440   Common risk variants for colorectal cancer: an evaluation of associations with age at cancer onset.

  28233817   Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study.

  28508326   The association of low penetrance genetic risk modifiers with colorectal cancer in lynch syndrome patients: a systematic review and meta-analysis.

  29147930   SNP association study in PMS2-associated Lynch syndrome.

  29547645   Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population.

  31038671   Colorectal cancer susceptibility variants and risk of conventional adenomas and serrated polyps: results from three cohort studies.

  31818908   Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

  32022527   Synchronous and multiple renal cell carcinoma, clear cell and papillary: An approach to clinically significant genetic abnormalities.

  32170005   Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.