SNP information rs1360780

Research and publications:

  15565110   Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.

  15637659   Linkage disequilibrium patterns and tagSNP transferability among European populations.

  17081296   Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits.

  18180755   Family-based association of FKBP5 in bipolar disorder.

  18191112   The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort.

  18349090   Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.

  18597649   Genetic variants in FKBP5 affecting response to antidepressant drug treatment.

  18702710   Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls.

  18803430   Pharmacogenetics of major depression: insights from level 1 of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial.

  19199039   Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder.

  19233472   Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection

  19455174   Psychobiology and molecular genetics of resilience.

  19540311   Genetics of anxiety and trauma-related disorders.

  19676097   FKBP5 polymorphisms and antidepressant response in geriatric depression.

  19924111   Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment.

  20008943   Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.

  20090668   Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide.

  20226536   Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort.

  20393453   Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder.

  20504254   Pharmacogenomics of suicidal events.

  20547006   FKBP5 and resistant attachment predict cortisol reactivity in infants: gene-environment interaction.

  20549395   Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies

  20551900   FKBP5 polymorphisms modify the effects of childhood trauma.

  20709156   Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders.

  20726698   Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals.

  20849924   Association study between a functional polymorphism of FK506-binding protein 51 (FKBP5) gene and personality traits in healthy subjects.

  20856915   Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters.

  21112363   Association of FKBP5 gene haplotypes with completed suicide in the Japanese population.

  21172166   Pharmacogenetics of antidepressant response.

  21225419   Gene-environment interactions: early life stress and risk for depressive and anxiety disorders.

  21316860   Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach.

  21333900   The role of genetics in IBS

  21449676   Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample.

  21483441   Impact of genetic variation in FKBP5 on clinical response in pediatric acute myeloid leukemia patients: a pilot study.

  21536970   Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.

  21654733   Moderation of adult depression by a polymorphism in the FKBP5 gene and childhood physical abuse in the general population.

  21788965   Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study examining polymorphisms of the GR and FKBP5 genes.

  21865530   Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study.

  22030708   Genome-wide association study of antidepressant treatment-emergent suicidal ideation.

  22134958   Relationship between FKBP5 polymorphisms and depression symptoms among kidney transplant recipients.

  22213790   Interaction between FKBP5 and childhood trauma and risk of aggressive behavior.

  22393204   Cannabinoid receptor genotype moderation of the effects of childhood physical abuse on anhedonia and depression.

  22459275   FKBP5 polymorphisms as vulnerability to anxiety and depression in patients with advanced gastric cancer: a controlled and prospective study.

  22738351   Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response.

  22781842   Variation in the glucocorticoid receptor gene at rs41423247 moderates the effect of prenatal maternal psychological symptoms on child cortisol reactivity and behavior.

  22825419   FK506-binding protein 51 (FKBP5) gene polymorphism is not associated with glucocorticoid therapy outcome in patients with idiopathic thrombocytopenic purpura.

  22979952   FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity.

  23733030   Pharmacogenetics in major depression: a comprehensive meta-analysis.

  23861224   Role of allelic variants of FK506-binding protein 51 (FKBP5) gene in the development of anxiety disorders.

  24099078   FKBP5 and CRHR1 polymorphisms moderate the stress-physical health association in a national sample.

  24128936   PharmGKB summary: venlafaxine pathway.

  24166410   HPA axis genetic variation, cortisol and psychosis in major depression.

  24253961   FKBP5 genotype and structural integrity of the posterior cingulum.

  24319431   Mechanisms of antidepressant resistance.

  24411633   Moderating role of FKBP5 genotype in the impact of childhood adversity on cortisol stress response during adulthood.

  24596569   Gene-environment interactions and intermediate phenotypes: early trauma and depression.

  24603855   FKBP5 moderates alcohol withdrawal severity: human genetic association and functional validation in knockout mice.

  24632812   Transcriptomic analysis of the effects of a fish oil enriched diet on murine brains.

  24636505   Effect of the common functional FKBP5 variant (rs1360780) on the hypothalamic-pituitary-adrenal axis and peripheral blood gene expression.

  24658422   Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance.

  24741566   Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy.

  24756342   Role of FKBP5 in emotion processing: results on amygdala activity, connectivity and volume.

  24766650   Drug addiction and stress-response genetic variability: association study in African Americans.

  24845178   Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype.

  24856550   FKBP5 polymorphism is associated with major depression but not with bipolar disorder.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  24959896   The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder.

  25088286   Association between the common functional FKBP5 variant (rs1360780) and brain structure in a non-clinical population.

  25331639   The common functional FKBP5 variant rs1360780 is associated with altered cognitive function in aged individuals.

  25462914   FKBP5 moderation of depressive symptoms in peer victimized, post-institutionalized children.

  25583614   HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children.

  25751398   Hypothalamic-pituitary-adrenal system, neurotrophic factors and clozapine response: association with FKBP5 and NTRK2 genes.

  26030911   Eye tracking indices of attentional bias in children of depressed mothers: Polygenic influences help to clarify previous mixed findings.

  26032970   Polymorphisms in the FK506 binding protein 5 gene are associated with attention deficit hyperactivity disorder and diurnal cortisol levels.

  26076833   Single-Nucleotide Polymorphism of the FKBP5 Gene and Childhood Maltreatment as Predictors of Structural Changes in Brain Areas Involved in Emotional Processing in Depression.

  26189450   Genetic Moderation of Stress Effects on Corticolimbic Circuitry.

  26272340   Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome.

  26399750   Research Letter: Childhood trauma and the rs1360780 SNP of FKBP5 gene in psychosis: a replication in two general population samples.

  26424418   Do common genotypes of FK506 binding protein 5 (FKBP5) moderate the effects of childhood maltreatment on cognition in schizophrenia and healthy controls?

  26424511   Psychiatric symptoms in adolescents: FKBP5 genotype--early life adversity interaction effects.

  26543368   Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.

  26595470   Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation.

  26630184   Association between FKBP5 Functional Polymorphisms and Completed Suicide.

  26645208   The FKBP5 polymorphism rs1360780 influences the effect of an algorithm-based antidepressant treatment and is associated with remission in patients with major depression.

  26801675   FKBP5 modulates the hippocampal connectivity deficits in depression: a study in twins.

  26813705   Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample.

  26885402   Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders.

  26982819   FKBP5 is associated with amygdala volume in the human brain and mood state: A voxel-based morphometry (VBM) study.

  27038411   STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5.

  27062383   The Effect of Nicotine on HPA Axis Activity in Females is Modulated by the FKBP5 Genotype.

  27078785   FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study.

  27126851   A Prospective Cohort Study of Influences on Externalizing Behaviors Across Childhood: Results From a Nurse Home Visiting Randomized Controlled Trial.

  27196697   FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students.

  27389186   The Interaction between Childhood Bullying and the FKBP5 Gene on Psychotic-Like Experiences and Stress Reactivity in Real Life.

  27448712   Associations between the FKBP5 haplotype, exposure to violence and anxiety in females.

  27528460   HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition.

  27601205   Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis.

  27648526   The influence of FKBP5 genotype on expression of FKBP5 and other glucocorticoid-regulated genes, dependent on trauma exposure.

  27664120   Reduced DNA methylation of FKBP5 in Cushing's syndrome.