SNP information rs12979860

Research and publications:

  19684573   Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

  19759533   Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

  20176026   Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin

  20184973   Interleukin-28b: a key piece of the hepatitis C virus recovery puzzle

  20235331   Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection

  20389235   Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients

  20399780   Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus

  20547162   Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction

  20578254   Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes

  20621700   An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response

  20633102   Hepatitis C: viral and host factors associated with non-response to pegylated interferon plus ribavirin

  20637200   A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice

  20648473   Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin

  20659305   A tetra-primer amplification refractory mutation system polymerase chain reaction for the evaluation of rs12979860 IL28B genotype

  20728570   Impact of IL28B genotype on the early and sustained virologic response in treatment-naïve patients with chronic hepatitis C

  20729732   Host genetic basis for hepatitis C virus clearance: a role for blood collection centers

  20803561   Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection

  20804372   Prediction of response to pegylated interferon plus ribavirin by IL28B gene variation in patients coinfected with HIV and hepatitis C virus

  20889274   IL28B polymorphisms and chronic hepatitis C

  20931559   IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C

  20950615   IL28B and the control of hepatitis C virus infection

  20964522   Modeling the probability of sustained virological response to therapy with pegylated interferon plus ribavirin in patients coinfected with hepatitis C virus and HIV

  20977343   IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection

  21068134   HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy

  21070502   Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort

  21080244   The IL-28 genotype: how it will affect the care of patients with hepatitis C virus infection

  21112657   Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients

  21112660   Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b

  21145807   Early virologic response and IL28B polymorphisms in patients with chronic hepatitis C genotype 3 treated with peginterferon alfa-2a and ribavirin

  21145813   Interferon-lambda serum levels in hepatitis C

  21146242   IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC

  21147186   Impact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection

  21147189   IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway

  21157362   Pharmacodynamics of PEG-IFN-[alpha]-2a and HCV response as a function of IL28B polymorphism in HIV/HCV-coinfected patients

  21228123   IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations

  21246582   Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir

  21254158   Quantitation of pretreatment serum interferon-γ-inducible protein-10 improves the predictive value of an IL28B gene polymorphism for hepatitis C treatment response

  21254179   Interleukin-28B polymorphisms are associated with histological recurrence and treatment response following liver transplantation in patients with hepatitis C virus infection

  21274371   Peginterferon and ribavirin treatment for hepatitis C virus infection

  21303914   Interferon lambdas: the next cytokine storm

  21345258   Prospects for personalizing antiviral therapy for hepatitis C virus with pharmacogenetics

  21346780   IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection

  21354446   IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C

  21360716   Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance

  21374656   IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection

  21375685   Different distributions of hepatitis C virus genotypes among HIV-infected patients with acute and chronic hepatitis C according to interleukin-28B genotype

  21376050   Coffee consumption is associated with response to peginterferon and ribavirin therapy in patients with chronic hepatitis C

  21378537   Association between IL28B gene polymorphisms and plasma HCV-RNA levels in HIV/HCV-co-infected patients

  21389156   The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with inter

  21390311   Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms

  21397726   Portal pressure predicts outcome and safety of antiviral therapy in cirrhotic patients with hepatitis C virus infection

  21413051   Genetic variation in interleukin 28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV-infected children

  21447862   Association of genetic variation in IL28B with hepatitis C treatment-induced viral clearance in the Chinese Han population

  21466653   Donor and recipient IL28B polymorphisms in HCV-infected patients undergoing antiviral therapy before and after liver transplantation

  21479134   IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection

  21488075   Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C

  21505315   IL28B gene polymorphisms and viral kinetics in HIV/hepatitis C virus-coinfected patients treated with pegylated interferon and ribavirin

  21537116   Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV–hepatitis C virus-coinfected patients with prior nonresponse or relapse

  21549150   Real-time polymerase chain reaction assay based on high-resolution melting analysis for the determination of the rs12979860 polymorphism involved in hepatitis C treatment response

  21572301   Low-density lipoprotein receptor genotyping enhances the predictive value of IL28B genotype in HIV/hepatitis C virus-coinfected patients

  21592993   Influence of interleukin-28B single-nucleotide polymorphisms on progression to liver cirrhosis in human immunodeficiency virus-hepatitis C virus-coinfected patients receiving antiretroviral therapy

  21600205   A polymorphism in IL28B distinguishes exposed, uninfected individuals from spontaneous resolvers of HCV infection

  21606533   Interleukin 28B gene variation at rs12979860 determines early viral kinetics during treatment in patients carrying genotypes 2 or 3 of hepatitis C virus

  21613433   Interleukin-28B genotyping by melt-mismatch amplification mutation assay PCR analysis using single nucleotide polymorphisms rs12979860 and rs8099917, a useful tool for prediction of therapy response in hepatitis C patients

  21626525   Limited use of interleukin 28B in the setting of response-guided treatment with detailed on-treatment virological monitoring

  21628662   IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C

  21647799   Role of interleukin 28B rs12979860 C/T polymorphism on the histological outcome of chronic hepatitis C: relationship with gender and viral genotype

  21670772   Importance of host genetic factors HLA and IL28B as predictors of response to pegylated interferon and ribavirin

  21692944   IL28B polymorphisms determine early viral kinetics and treatment outcome in patients receiving peginterferon/ribavirin for chronic hepatitis C genotype 1

  21694902   New strategies for the treatment of hepatitis C virus infection and implications of resistance to new direct-acting antiviral agents

  21703198   Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C

  21703201   The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation

  21704279   Simultaneous genotyping of rs12979860 and rs8099917 variants near the IL28B locus associated with HCV clearance and treatment response

  21721028   Genetic variation in the interleukin-28B gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection

  21722179   Predicting response to therapy in chronic hepatitis C: an approach combining interleukin-28B gene polymorphisms and clinical data

  21726252   IL28B rs12979860 C/T polymorphism in elderly chronic hepatitis C patients treated with pegylated-interferon and ribavirin

  21739451   Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state

  21742841   IL28B genotype effects during early treatment with peginterferon and ribavirin in difficult-to-treat hepatitis C virus infection

  21790472   IL28B polymorphism associated with spontaneous clearance of hepatitis C infection in a Southern Brazilian HIV type 1 population

  21813376   Progression of liver fibrosis in HIV/HCV genotype 1 co-infected patients is related to the T allele of the rs12979860 polymorphism of the IL28B gene

  21820962   Interferon-lambda and therapy for chronic hepatitis C virus infection

  21854194   Distribution of polymorphisms in cytochrome P450 2B6, histocompatibility complex P5, chemokine coreceptor 5, and interleukin 28B genes in inhabitants from the central area of Argentina

  21884576   Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort

  21889215   IL28B polymorphisms are not associated with the response to interferon-β in multiple sclerosis

  21889467   Determination of IL28B polymorphisms in liver biopsies obtained after liver transplantation

  21898478   Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response

  21900787   A single IL28B genotype SNP rs12979860 determination predicts treatment response in patients with chronic hepatitis C Genotype 1 virus

  21903134   Interleukin 28B genotype determination using DNA from different sources: A simple and reliable tool for the epidemiological and clinical characterization of hepatitis C

  21907615   Polymorphism near the IL28B gene in Korean hepatitis C virus-infected patients treated with peg-interferon plus ribavirin

  21911885   Genetic variation in interleukin-28B predicts SVR in hepatitis C genotype 1 Argentine patients treated with PEG IFN and ribavirin

  21918436   Host genetics

  21931540   IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study

  21932410   Treatment of chronic hepatitis C genotype 1 patients at an academic center in Europe involved in prospective, controlled trials: is there a selection bias?

  21932415   Interleukin 28B polymorphism predicts pegylated interferon plus ribavirin treatment outcome in chronic hepatitis C genotype 4

  21933876   Genetic polymorphism in IL28B is associated with spontaneous clearance of hepatitis C virus genotype 4 infection in an Egyptian cohort

  21951981   IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C

  21971821   Efficacy of chronic hepatitis C therapy with pegylated interferon and ribavirin in patients on methadone maintenance treatment

  21974859   Association between IL28B polymorphisms and first-phase viral load decrease in chronic hepatitis C virus-infected patients treated with peginterferon alfa-2b/ribavirin

  21983945   Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C