SNP information rs12422149

Research and publications:

  19077707   Pharmacogenetics of asthma.

  19151602   Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response.

  19665766   Genetics and pharmacogenetics of the leukotriene pathway.

  20974993   Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast.

  21266523   Expression of SLCO transport genes in castration-resistant prostate cancer and impact of genetic variation in SLCO1B3 and SLCO2B1 on prostate cancer outcomes.

  21606417   SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.

  22280100   Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions.

  22966888   Integrative systems biology approaches in asthma pharmacogenomics.

  23151832   SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.

  23666051   SLCO2B1 genetic polymorphisms in a Korean population: pyrosequencing analyses and comprehensive comparison with other populations.

  23876492   Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care.

  23896625   Polymorphisms of the androgen transporting gene SLCO2B1 may influence the castration resistance of prostate cancer and the racial differences in response to androgen deprivation.

  24598718   Identification of the effect of multiple polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid using a population-modeling approach.

  24701578   The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  26668348   Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer.

  27583031   Targeting intratumoral androgens: statins and beyond.

  27648838   Single Nucleotide Polymorphisms in Cellular Drug Transporters Are Associated with Intolerance to Antiretroviral Therapy in Brazilian HIV-1 Positive Individuals.

  28389510   Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer.

  28627804   The Effect of Genetic Polymorphisms in SLCO2B1 on the Lipid-Lowering Efficacy of Rosuvastatin in Healthy Adults with Elevated Low-Density Lipoprotein.

  30587554   Germline Variant in SLCO2B1 and Response to Abiraterone Acetate Plus Prednisone (AA) in New-onset Metastatic Castration-resistant Prostate Cancer (mCRPC).

  31240859   Association between genetic polymorphisms of SLCO1B1 and susceptibility to methimazole-induced liver injury.

  31872004   Data on a genome-wide association study of type 2 diabetes in a Maya population.

  33921650   Prostate Cancer Mortality Associated with Aggregate Polymorphisms in Androgen-Regulating Genes: The Atherosclerosis Risk in the Communities (ARIC) Study.

  35600302   Klotho Polymorphism in Association With Serum Testosterone and Knee Strength in Women After Testosterone Administration.

  35887565   Pharmacogenomics of Leukotriene Modifiers: A Systematic Review and Meta-Analysis.