SNP information rs11708067

Research and publications:

  20081857   Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

  20081858   New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

  20185807   Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

  20372150   Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.

  20490451   Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

  20581827   Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

  20693352   Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20805255   Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult population

  20870969   Genetic predisposition to long-term nondiabetic deteriorations in glucose homeostasis: Ten-year follow-up of the GLACIER study

  20886378   Physiologic characterization of type 2 diabetes-related loci

  21091714   The genetics of type 2 diabetes: what have we learned from GWAS?

  21103350   Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese

  21188353   Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans

  21378175   Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program

  21421807   Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men

  21515849   Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

  21712988   Absence of birth-weight lowering effect of ADCY5 and near CCNL, but association of impaired glucose-insulin homeostasis with ADCY5 in Asian Indians.

  21789219   Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children.

  21810599   Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis

  21887289   Glucose-raising genetic variants in MADD and ADCY5 impair conversion of proinsulin to insulin

  21949744   Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes

  22046406   Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese

  22233651   A genome-wide association study of gestational diabetes mellitus in Korean women

  22698489   Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study.

  22708638   Effect of communicating genetic and phenotypic risk for type 2 diabetes in combination with lifestyle advice on objectively measured physical activity: protocol of a randomised controlled trial

  22984506   Effects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program

  23013243   Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children

  23073174   From genotype to human β cell phenotype and beyond

  23185617   Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants

  23193118   Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium

  23462794   Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

  23761423   Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes

  24740569   ADCY5 couples glucose to insulin secretion in human islets.

  24843659   Insights into the genetic basis of type 2 diabetes.

  24864266   Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.

  24926958   Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent.

  25145545   Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?

  25774817   Genetics of type 2 diabetes-pitfalls and possibilities.

  25793868   ADCY5 gene expression in adipose tissue is related to obesity in men and mice.

  26818947   Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.

  26977395   Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes.

  27049325   Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study.

  27053236   Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

  27782183   Evaluating the transferability of 15 European-derived fasting plasma glucose SNPs in Mexican children and adolescents.

  28684635   A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus.

  28821857   CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.

  28919193   Association analysis of genetic variants with metabolic syndrome components in the Moroccan population.

  30089489   Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women.

  31123324   ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.

  33193614   The Role of Genetically Determined Glycemic Traits in Breast Cancer: A Mendelian Randomization Study.

  34169461   Association of diabetes-related variants in ADCY5 and CDKAL1 with neonatal insulin, C-peptide, and birth weight.

  34440550   ADCY5, CAPN10 and JAZF1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes.

  34801028   Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.