Research and publications:
18806885 Genetic analysis of the clusterin gene in pseudoexfoliation syndrome.
19734902 Genome-wide association study identifies CLU and PICALM variants associated with Alzheimer's disease.
19734903 Genome-wide association study identifies CLU and CR1 variants associated with Alzheimer's disease.
19808789 Genome-wide association studies in Alzheimer's disease.
20209083 Genetic variation in CLU and its association with Alzheimer's disease.
20236449 Genetics of Alzheimer disease in the pre- and post-GWAS era.
20410100 Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos.
20460622 Genome-wide analysis of genetic loci associated with Alzheimer disease
20534741 Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
20554627 Replication of CLU, CR1, and PICALM associations with alzheimer disease.
20558387 Genetic variation and neuroimaging measures in Alzheimer disease.
20570404 Association of CLU and PICALM variants with Alzheimer's disease.
20594621 Genetic architecture of Alzheimer's disease: beyond APP, PSEN and APOE.
20599866 Significance of CLU gene polymorphism in Chinese patients with Alzheimer's disease.
20603455 Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease.
20697030 Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
20738160 Association analysis between the rs11136000 single nucleotide polymorphism in clusterin gene, rs3851179 single nucleotide polymorphism in clathrin assembly lymphoid myeloid protein gene and the patients with schizophrenia in the Chinese populati
20739100 Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old.
20885792 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
21059989 Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals.
21124753 Alzheimer's disease: diagnosis, prognosis and path to prevention.
21132329 Study of 15 candidate genes responsible for late-onset Alzheimer's disease.
21152065 A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis.
21321396 Replication of the association of BIN1 with Alzheimer's disease and assessment of genetic interactions.
21347408 Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers of Alzheimer's disease.
21358043 PICALM and CR1 variants are not associated with sporadic Alzheimer's disease in Chinese patients.
21379329 Genome-wide association of late-onset familial Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
21390209 Meta-analysis of a genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
21391232 CR1 is associated with amyloid plaque burden and age-related cognitive decline.
21397462 Neuronal hyperactivation in carriers of the Alzheimer's disease risk variant for the clusterin gene.
21422520 Association of Alzheimer's disease clusterin risk allele with plasma clusterin concentration.
21459483 Using cerebrospinal fluid biomarkers to replicate genetic associations in Alzheimer's disease.
21466683 The CLU, CR1 and PICALM genes are associated with senile plaques associated with Alzheimer's disease.
21547229 Neuroimaging indicators as endophenotypes in Alzheimer's disease.
21726919 CR1 genotype is associated with entorhinal cortex volume in young healthy adults.
21825236 Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease.
21892414 Alzheimer's disease risk variants in the clusterin gene are associated with alternative splicing.
21912625 An exploratory study on CLU, CR1 and PICALM and Parkinson disease.
22005930 Genome-wide study of the association of Alzheimer's disease with psychotic symptoms.
22015308 Polymorphisms of CR1, CLU and PICALM determine susceptibility to Alzheimer's disease in a population of southern China.
22047634 Alzheimer's Disease Neuroimaging Initiative: A review of articles published since its inception.
22122982 Association of clusterin gene polymorphisms with late-onset Alzheimer's disease.
22159054 A comprehensive genetic association study of Alzheimer disease in African Americans.
22191060 Genetics of late-onset Alzheimer's disease: Alzheimer's database update and common pathway analysis.
22216291 Association between IgM anti-herpes simplex virus and plasma amyloid-beta levels.
22248099 Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk.
22303368 Multilocus genetic analysis of brain images.
22402018 Implication of common and disease specific variants in CLU, CR1, and PICALM.
22482072 Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.
22722634 Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
22795969 Alzheimer risk variant CLU and brain function during aging.
22833209 Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment.
22911757 Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.
23429712 A panel of genetic variations as a potential non-invasive biomarker for early diagnosis of Alzheimer's disease.
23573206 Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.
23892938 The rs11136000 variant of the CLU gene is significantly associated with Alzheimer's disease in Caucasian and Asian populations.
24117116 Plasma clusterin levels and rs11136000 genotype in individuals with mild cognitive impairment and Alzheimer's disease.
24578178 Effects of Alzheimer's disease-associated PICALM and CLU variants on hippocampal functional connectivity in healthy young adults.
24643340 Genotype patterns at CLU, CR1, PICALM and APOE, cognition and Mediterranean diet: the PREDIMED-NAVARRA trial.
24670887 Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.
24958191 Clusterin variants are not associated with southern Chinese patients with Alzheimer's disease.
25051234 Intracellular clusterin interacts with brain isoforms of bridge integrator 1 and microtubule-associated protein Tau in Alzheimer's disease.
25108264 Genomics in neurological disorders.
25189118 Risk variants for late-onset Alzheimer's disease include memory loss, mild cognitive impairment, and Alzheimer's disease.
25359311 Association of MTHFR and PICALM polymorphisms with Alzheimer's disease.
25426068 Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.
25633098 The CLU rs9331888 polymorphism promotes susceptibility to Alzheimer's disease in Caucasian but not East Asian populations.
25849827 Evaluation of genetic polymorphisms in clusterin and tumor necrosis factor-alpha genes in South Indian individuals with pseudoexfoliation syndrome.
26154020 A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia.
26343804 Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults.
26449541 Interaction between CLU and MS4A4E variants modulates Alzheimer's disease risk.
26661731 ApoA1, ApoJ and ApoE Plasma Levels and Genotype Frequencies in Cerebral Amyloid Angiopathy.
26680604 Polygenic analysis of late-onset Alzheimer's disease in mainland China.
26788404 Association of BACE1 gene polymorphism with Parkinson's disease in a Norwegian population.
26899953 Factor immunity promotes changes in functional brain networks in people at risk for Alzheimer's disease: Evidence from neuroimaging and genetics.
26993346 Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.
27017968 Impact of PICALM and CLU on hippocampal degeneration.
27076484 The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort.
27229352 Impact of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy individuals with mild cognitive impairment and Alzheimer's disease cohorts.
27239546 Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: the Australian Aging Study in Imaging, Biomarkers and Lifestyle.
27274215 Genes associated with Alzheimer's disease: review and current status.
27482534 Alzheimer's disease genetic risk assessment predicts longitudinal thinning of hippocampal subregions in healthy older adults.
27516739 Plasma Clusterin and the CLU Gene rs11136000 Variant Are Associated with Mild Cognitive Impairment in Type 2 Diabetic Patients.
27610127 Analysis of heterogeneous multimodal biomarkers of Alzheimer's disease using a Bayesian network.
27882096 Association between clusterin gene rs11136000 polymorphism and susceptibility to late-onset Alzheimer's disease: a review and meta-analysis of case-control studies.
28084078 Association of major GWAS genes with late-onset Alzheimer's disease in a Colombian population.
28233427 General effects of the clusterin gene on the default mode network among individuals at risk for Alzheimer's disease.
28316001 Associations of Alzheimer's disease candidate gene polymorphisms BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance.
28558900 Effect of CLU and PICALM polymorphisms on AD risk: A study from south India.
28631188 The role of CLU, PICALM and TNK1 genotypes in aging with and without Alzheimer's disease.
28870582 Association of Alzheimer's disease and type 2 diabetes: new common susceptibility genes discovered by the cFDR approach.
28972394 Association Between Clusterin Gene Polymorphisms and Epilepsy in a Han Chinese Population.
29396813 Association between the rs11136000 polymorphism of the CLU gene and Alzheimer's disease: an updated meta-analysis.
29504051 Updated meta-analysis of BIN1, CR1, MS4A6A, CLU, and ABCA7 variants in Alzheimer's disease.
30038359 Analysis of 74,248 samples confirms an association between the CLU rs11136000 polymorphism and Alzheimer's disease in Caucasians but not in Chinese.
30503753 Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls.
30560405 Informative combination of CLU rs11136000, serum HDL levels, diabetes, and age as a new piece of puzzle-picture of predictive medicine for cognitive disorders.
31469155 Combined risk effect of BIN1, CLU and APOE genes in Alzheimer's disease.
31930747 CLU rs11136000 contributes to early cognitive decline in Parkinson's disease.
