SNP information rs110402

Research and publications:

  15297935   Linkage disequilibrium and association of MAPT H1 in Parkinson disease.

  17467808   Genetic variability at HPA axis in major depression and clinical response to antidepressant treatment.

  18250257   Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.

  18349090   Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.

  19409562   Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men.

  19596121   Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity.

  19736354   Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension.

  19750552   Risk and resilience: genetic and environmental influences on development of the stress response.

  19772600   A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data.

  19878140   H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence.

  20010888   The CRF system, stress, depression and anxiety-insights from human genetic studies.

  20029939   Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms.

  20161813   Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene.

  20374216   Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence.

  21172166   Pharmacogenetics of antidepressant response.

  21193270   Genetic moderators and psychiatric mediators of the link between sexual abuse and alcohol dependence.

  21223300   The limbic-hypothalamic-pituitary-adrenal axis and the development of alcohol use disorders in youth.

  21225419   Gene-environment interactions: early life stress and risk for depressive and anxiety disorders.

  21438878   Moderation of the association between childhood maltreatment and neuroticism by the corticotropin-releasing hormone receptor 1 gene.

  21711518   Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

  21810631   Prediction of the risk of comorbid alcoholism in schizophrenia by interaction of common genetic variants in the corticotropin-releasing factor system.

  21978546   Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.

  21998007   A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women.

  22018085   Interactive effects of corticotropin releasing hormone receptor 1, serotonin transporter linked polymorphic region, and child maltreatment on diurnal cortisol regulation and internalizing symptomatology.

  22122881   Molecular and cell signaling targets for PTSD pathophysiology and pharmacotherapy.

  22378896   Variation in the corticotropin-releasing hormone receptor 1 (CRHR1) gene influences fMRI signal responses during emotional stimulus processing.

  22467522   Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population.

  22536069   Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment.

  22748421   Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults: findings from a longitudinal study.

  22957021   Corticotropin-releasing hormone receptor 1 gene variants in irritable bowel syndrome.

  23274505   Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults.

  23294766   Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism.

  23473364   The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects.

  24166410   HPA axis genetic variation, cortisol and psychosis in major depression.

  24319431   Mechanisms of antidepressant resistance.

  24596569   Gene-environment interactions and intermediate phenotypes: early trauma and depression.

  24703172   CRHR1 genotype and history of maltreatment predict cortisol reactivity to stress in adolescents.

  24741566   Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy.

  24931706   Interaction of early life stress and corticotropin-releasing hormone receptor gene: effects on working memory.

  25541005   Variation in the corticotropin-releasing hormone receptor 1 (CRHR1) gene modulates age effects on working memory.

  25583614   HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children.

  26189450   Genetic Moderation of Stress Effects on Corticolimbic Circuitry.

  26260058   Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth.

  26518448   Case-control study of glucocorticoid receptor and corticotrophin-releasing hormone receptor gene variants and risk of perinatal depression.

  26543368   Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.

  26595470   Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation.

  26808377   Corticotropin-Releasing Hormone Receptor 2 Gene Variants in Irritable Bowel Syndrome.

  26923505   Interactions Between Anandamide and Corticotropin-Releasing Factor Signaling Modulate Human Amygdala Function and Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions.

  27497153   Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response.

  27544317   Effects of corticotropin-releasing hormone receptor 1 SNPs on major depressive disorder are influenced by sex and smoking status.

  27642547   Genetic and Environmental Factors Associated with Cannabis Involvement.

  27894002   Polymorphism in CRHR1 gene affects the IL-1β levels in suicidal attempters.

  28237884   Effects of crack cocaine addiction and stress-related genes on peripheral BDNF levels.

  28364727   Hypothalamic-pituitary-adrenal axis genetic variation and early stress moderates amygdala function.

  28461011   The interaction of corticotropin-releasing hormone receptor gene and early life stress on emotional empathy.

  28793974   Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder.

  29755375   Influence of CRHR1 Polymorphisms and Childhood Abuse on Suicide Attempts in Affective Disorders: A GxE Approach.

  30319260   HPA-axis genes as potential risk variants for neurocognitive decline in trauma-exposed, HIV-positive females.

  30390684   DNA methylation levels are associated with CRF(1) receptor antagonist treatment outcome in women with post-traumatic stress disorder.

  30447186   Effect of corticotropin-releasing hormone receptor1 gene variation on psychosocial stress reaction via the dorsal anterior cingulate cortex in healthy adults.

  30874897   Effect of CRHR1 and CRHR2 gene polymorphisms and childhood trauma in suicide attempt.

  30949563   FAAH genotype, CRFR1 genotype, and cortisol interact to predict anxiety in an aging, rural Hispanic population: A Project FRONTIER study.

  30953926   Interactive effects of corticotropin-releasing hormone receptor 1 gene and work stress on burnout in medical professionals in a Chinese Han population.

  31902387   Gene-environment interactions between HPA-axis genes and childhood maltreatment in depression: a systematic review.

  31959877   Aneurysmal subarachnoid haemorrhage: Effect of CRHR1 genotype on mental health-related quality of life.

  32305063   Aneurysmal subarachnoid haemorrhage: effect of CRHR1 genotype on fatigue and depression.

  32361186   Salivary cortisol response to psychosocial stress in the late evening depends on CRHR1 genotype.

  32576619   Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders.

  32697690   Interactions of childhood maltreatment and genetic variations in adult depression: A systematic review.

  32757697   Further evidence for the association of GAL, GALR1 and NPY1R variants with opioid dependence.

  33019527   The Pathways between Cortisol-Related Regulation Genes and PTSD Psychotherapy.

  34279801   The role of rs242941, rs1876828, rs242939 and rs110402 polymorphisms of CRHR1 gene and the depression: systematic review and meta-analysis.

  35718217   Relations among CRFR1 and FKBP5 genotype, cortisol, and cognitive function in aging humans: A Project FRONTIER study.