SNP information rs10741657

Research and publications:

  17607662   CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans.

  19783860   A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy

  20541252   Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

  21431378   Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis.

  21441443   Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes

  21828234   Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women

  21853245   The determinants of serum vitamin D levels in participants in a melanoma case-control study living in a temperate climate.

  22112344   Seasonal variation in 25-hydroxyvitamin D concentrations in the cardiovascular health study.

  22205958   Common variation in vitamin D pathway genes predicts circulating 25-hydroxyvitamin D Levels among African Americans.

  22357570   The Peru Urban versus Rural Asthma (PURA) Study: methods and baseline quality control data from a cross-sectional investigation into the prevalence, severity, genetics, immunology and environmental factors affecting asthma in adolescence in Peru

  22583563   Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore.

  22629401   Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

  22649517   Polymorphisms related to the serum 25-hydroxyvitamin D level and risk of myocardial infarction, diabetes, cancer and mortality. The Tromsø Study.

  22673963   Genome-wide association analysis of circulating vitamin D levels in children with asthma.

  22690899   Impaired vitamin D activation and association with CYP24A1 haplotypes in differentiated thyroid carcinoma.

  22701574   Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis.

  22740028   An exploratory analysis of common genetic variants in the vitamin D pathway including genome-wide associated variants in relation to glioma risk and outcome.

  22801813   The GC, CYP2R1 and DHCR7 genes are associated with vitamin D levels in northeastern Han Chinese children.

  23319826   Vitamin D and mortality: a Mendelian randomization study.

  23416105   Vitamin D status and gene transcription in immune cells.

  23456391   Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes.

  23730842   Association of vitamin D serum levels and its common genetic determinants, with severity of liver fibrosis in genotype 1 chronic hepatitis C patients.

  23793229   Association of common gene variants in vitamin D modulating genes and colon cancer recurrence.

  24516573   Vitamin D levels vary during antiviral treatment but are unable to predict treatment outcome in HCV genotype 1 infected patients.

  24868205   Vitamin D Binding Protein Impact on 25-Hydroxyvitamin D Levels under Different Physiologic and Pathologic Conditions.

  24934498   Real-life use of vitamin D3-fortified bread and milk during a winter season: the effects of CYP2R1 and GC genes on 25-hydroxyvitamin D concentrations in Danish families, the VitmaD study.

  25003556   Triangular relationship between single nucleotide polymorphisms in the CYP2R1 gene (rs10741657 and rs12794714), 25-hydroxyvitamin d levels, and coronary artery disease incidence.

  25046415   The functional polymorphisms of VDR, GC and CYP2R1 are involved in the pathogenesis of autoimmune thyroid diseases.

  25281353   Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study.

  25405862   Vitamin D insufficiency in Arabs and South Asians positively associates with polymorphisms in GC and CYP2R1 genes.

  25527766   Common variants in CYP2R1 and GC genes are both determinants of serum 25-hydroxyvitamin D concentrations after UVB irradiation and after consumption of vitamin D₃-fortified bread and milk during winter in Denmark.

  25533295   Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.

  25738688   Meta-analysis on vitamin D receptor and cancer risk: focus on the role of TaqI, ApaI, and Cdx2 polymorphisms.

  25981321   No evidence that genetically reduced 25-hydroxyvitamin D is associated with increased risk of ischaemic heart disease or myocardial infarction: a Mendelian randomization study.

  26038244   Genetic Variation in CYP2R1 and GC Genes Associated With Vitamin D Deficiency Status.

  26073892   Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study.

  26141257   Low vitamin D status is associated with more depressive symptoms in Dutch older adults.

  26177022   Association of VDR and CYP2R1 Polymorphisms with Mite-Sensitized Persistent Allergic Rhinitis in a Chinese Population.

  26275945   Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study.

  26383826   Association of rs7041 and rs4588 Polymorphisms of the Vitamin D Binding Protein and the rs10741657 Polymorphism of CYP2R1 with Vitamin D Status Among Jordanian Patients.

  26416604   Vitamin D metabolism-related genetic variants, dietary protein intake and improvement of insulin resistance in a 2 year weight-loss trial: POUNDS Lost.

  26446360   Mendelian randomization studies of biomarkers and type 2 diabetes.

  26448018   Variants in Vitamin D Binding Protein Gene Are Associated With Gestational Diabetes Mellitus.

  26692013   Re-Examining the Association between Vitamin D and Childhood Caries.

  26867646   Specific polymorphisms in the vitamin D metabolism pathway are not associated with susceptibility to Chlamydia trachomatis infection in humans.

  26872154   Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants.

  26911666   Integrative role of vitamin D related and Interleukin-28B genes polymorphism in predicting treatment outcomes of Chronic Hepatitis C.

  27215954   Investigating causality in the association between 25(OH)D and schizophrenia.

  27473187   CYP2R1 polymorphisms are important modulators of circulating 25-hydroxyvitamin D levels in elderly females with vitamin insufficiency, but not of the response to vitamin D supplementation.

  27570856   Genetic influence on circulating vitamin D among Saudi Arabians.

  27625044   Genetically Low Vitamin D Levels, Bone Mineral Density, and Bone Metabolism Markers: a Mendelian Randomisation Study.

  27652346   Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk.

  27768857   Effects of Genetic and Nongenetic Factors on Total and Bioavailable 25(OH)D Responses to Vitamin D Supplementation.

  28079136   SNP rs11185644 of RXRA gene is identified for dose-response variability to vitamin D3 supplementation: a randomized clinical trial.

  28253304   Bone mineral density is associated with vitamin D related rs6013897 and estrogen receptor polymorphism rs4870044: The Tromsø study.

  28382877   Common genetic variants are associated with lower serum 25-hydroxyvitamin D concentrations across the year among children at northern latitudes.

  28575224   Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants.

  28594127   There is no clear support for a role of vitamin D in Parkinson's disease: a Mendelian randomized trial.

  29089348   Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.

  29291743   SNPs related to vitamin D and breast cancer risk: a case-control study.

  29476721   C3-epimerization of 25-hydroxyvitamin D increases with increasing serum 25-hydroxyvitamin D levels and shows a high degree of tracking over time.

  29502202   Association between vitamin D metabolism gene polymorphisms and asthma risk in Tunisian adults.

  29514138   Effects of Gene Variants Controlling Vitamin D Metabolism and Serum Levels on Hepatic Steatosis.

  29528271   Genetic polymorphisms of vitamin D3 metabolizing CYP24A1 and CYP2R1 enzymes in Turkish patients with ischemic stroke.

  29718335   Negative effect of vitamin D on kidney function: a Mendelian randomization study.

  29718904   Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

  29748306   Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study.

  29750155   Association between Subclinical Low Serum 25(OH)D in Donors and Fatty Liver Disease in Recipients after Living Donor Liver Transplantation.

  29750416   Serum 25-Hydroxyvitamin D, Plasma Lipids, and Associated Gene Variants in Prepubertal Children.

  29925546   Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study.

  29935100   Genetic polymorphisms of the hepatic pathways of fatty liver disease after living donor liver transplantation.

  29937467   Association among genetic variants in the vitamin D pathway and circulating 25-hydroxyvitamin D levels in Korean adults: results from the Korea National Health and Nutrition Examination Survey 2011-2012.

  29947775   Vitamin D and Inflammatory Bowel Disease: Mendelian Randomization Analyses in the Copenhagen Studies and UK Biobank.

  30120973   Effects of CYP2R1 gene variants on vitamin D levels and status: A systematic review and meta-analysis.

  30192652   Associations of genetic polymorphisms of the vitamin D pathway with blood pressure in a Han Chinese population.

  30405883   Variability in genes regulating vitamin D metabolism is associated with vitamin D levels in type 2 diabetes.

  30465296   Potential causal associations of serum 25-hydroxyvitamin D with lipids: a Mendelian randomization approach of the HUNT study.

  30475961   Genetically determined vitamin D levels and change in bone density during a weight-loss diet intervention: the Preventing Overweight Using Novel Dietary Strategies (POUNDS Lost) Trial.

  30609725   Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts.

  30624776   A variant in CYP2R1 predicts circulating vitamin D levels after supplementation with high-dose of vitamin D in healthy adolescent girls.

  30716477   There is no association between vitamin D status and the risk of developing Barrett's esophagus or esophageal adenocarcinoma: a Mendelian randomized trial.

  30796319   Vitamin D Receptor Polymorphism and DHCR7 Contribute to the Abnormal Interplay Between Vitamin D and Lipid Profile in Rheumatoid Arthritis.

  30942619   Role of VDR, GC, and CYP2R1 Polymorphisms in the Development of Hepatocellular Carcinoma in Hepatitis C Virus-Infected Patients.

  31206955   Vitamin D level and gene polymorphisms in Korean children with type 1 diabetes.

  31218665   Is there a causal relationship between vitamin D and melanoma risk? A Mendelian randomization study.

  31520221   Impact of CYP2R1, CYP27A1 and CYP27B1 genetic polymorphisms controlling vitamin D metabolism on susceptibility to hepatitis C virus infection in a high-risk Chinese population.

  31572458   Genes and metabolic pathway of sarcoidosis: identification of key players and risk modifiers.

  31625015   Genetic Polymorphisms in the Vitamin D Pathway and Non-small Cell Lung Cancer Survival.

  31814925   Association of circulating 25-hydroxyvitamin D levels with hypertension and blood pressure values in Korean adults: A Mendelian randomization study on a subset of the Korea National Health and Nutrition Survey 2011-2012 population.

  31881507   Variants in gene encoding for vitamin D binding protein were associated with leukocyte telomere length: The Pró-Saúde Study.

  31959263   Vitamin D-related genes and cardiometabolic markers in healthy children: a Mendelian randomisation study.

  32012190   Associations between common polymorphisms in CYP2R1 and GC, Vitamin D intake and risk of colorectal cancer in a prospective case-cohort study in Danes.

  32517587   Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.

  32542627   Vitamin D in Type 2 Diabetes: Genetic Susceptibility and the Response to Supplementation.

  32593521   Higher levels of 25-hydroxyvitamin D are associated with an increased risk of Bechsche's disease.

  32915988   Association of Vitamin D Pathway Gene CYP27B1 and CYP2R1 Polymorphisms with Autoimmune Endocrine Disorders: A Meta-Analysis.

  32939414   Association of vitamin D gene polymorphisms in children with asthma - A systematic review.

  33109689   Low vitamin D and risk of bacterial pneumonias: Mendelian randomisation studies in two population-based cohorts.

  33170161   Genetic test for the prescription of diets in support of physical activity.