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SNP information rs10505477

RS10505477

Normal allele: GG

Genetic variation in 8q24 is associated with colorectal cancer risk.

Polymorphism rs10505477 is related to topics like this:

Colorectal cancer genes

One of the prevalent cancer syndromes that can be inherited is colon cancer. Chromosome 2 contains...


Research and publications:

  17630503   Genetic variation in 8q24 associated with risk of colorectal cancer.

  18056436   Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.

  18372901   Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

  18535017   Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.

  18577746   Multiple loci with different cancer specificities within the 8q24 gene desert.

  18670647   Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer.

  18839428   Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample.

  18973230   Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations.

  19155440   Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.

  19520795   Novel single nucleotide polymorphism associations with colorectal cancer on chromosome 8q24 in African and European Americans.

  19690179   Functional and clinical significance of variants localized to 8q24 in colon cancer.

  20158306   Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer.

  20437058   The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.

  20530236   Genetic variation at chromosome 8q24 in osteosarcoma cases and controls.

  20585100   Genome-wide association studies of cancer.

  20978189   Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer.

  21036793   Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field

  21102338   Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer.

  21129217   Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis.

  21455501   Genetic variants on chromosome 8q24 and colorectal neoplasia risk: a case-control study in China and a meta-analysis of the published literature.

  21722176   Association of 8q24.21 loci with the risk of colorectal cancer: a systematic review and meta-analysis.

  21779458   Chromosome 8q24-Associated Cancers and MYC.

  22142333   Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development.

  22234922   8q24 risk alleles in West African and Caribbean men.

  22363440   cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

  22367214   Characterization of gene-environment interactions for colorectal cancer susceptibility loci.

  22558003   The 8q24 gene desert: an oasis of non-coding transcriptional activity.

  22848671   Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

  22985493   Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis.

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  24013564   Use of extremely short Förster resonance energy transfer probes in real-time polymerase chain reaction.

  24727911   Germline variation in colorectal risk Loci does not influence treatment effect or survival in metastatic colorectal cancer.

  24740154   Genome-wide association scan for variants associated with early-onset prostate cancer.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  24968322   Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.

  24978480   A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis.

  25046748   Clinical significance of POU5F1P1 rs10505477 polymorphism in Chinese gastric cancer patients receving cisplatin-based chemotherapy after surgical resection.

  25302443   Genetic variant in 8q24 is associated with prognosis for gastric cancer in a Chinese population.

  25956580   A colorectal cancer prediction model using traditional and genetic risk scores in Koreans.

  26078566   Association of colorectal cancer susceptibility variants with esophageal cancer in a Chinese population.

  26824036   Potentially Functional Polymorphisms in POU5F1 Gene Are Associated with the Risk of Lung Cancer in Han Chinese.

  26940994   GWASeq: targeted re-sequencing follow up to GWAS.

  27079684   Genome-wide association studies and epigenome-wide association studies go together in cancer control.

  27146020   Colorectal cancer risk genes are functionally enriched in regulatory pathways.

  27207650   Genome-wide association study of colorectal cancer in Hispanics.

  27249003   Clinical Significance of Long Non-Coding RNA CASC8 rs10505477 Polymorphism in Lung Cancer Susceptibility, Platinum-Based Chemotherapy Response, and Toxicity.

  27499173   A technical application of quantitative next generation sequencing for chimerism evaluation.

  27630819   Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data.

  28084440   Common risk variants for colorectal cancer: an evaluation of associations with age at cancer onset.

  28139693   Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer.

  29228715   Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

  29445242   Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development.

  29547645   Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population.

  30170403   Cumulative evidence for relationships between multiple variants in 8q24 and colorectal cancer incidence.

  30194776   Genetic susceptibility in the development of colorectal adenomas according to family history of colorectal cancer.

  30214306   Association between lncRNA CASC8 polymorphisms and the risk of cancer: a meta-analysis.

  30337837   Single nucleotide polymorphisms and sporadic colorectal cancer susceptibility: a field synopsis and meta-analysis.

  31818908   Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

  32213001   UEG Week 2019 Poster Presentations.

  32590746   Cumulative evidence of relationships between multiple variants in 8q24 region and cancer incidence.

  33727749   Genome-wide association study of serum prostate-specific antigen levels based on 1000 Genomes imputed data in Japanese: the Japan Multi-Institutional Collaborative Cohort Study.

Gastrointestinal tract cancer

The occurrence of gastrointestinal (GI) tract cancers caused by genetic mutations is widespread...

Hereditary gastric cancer

Gastric cancer is the third leading cause of cancer-related deaths worldwide, with a 5-year...

Pancreas cancer genetic

Up to 15% of pancreatic cancers are attributed to gene mutations that are passed down through...

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