SNP information rs10069690

Research and publications:

  20549820   Telomere length and genetic analyses in population-based studies of endometrial cancer risk.

  21269955   [hTERT single nucleotide polymorphism is associated with increased risks of hepatocellular carcinoma and tumor metastasis].

  22037553   A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.

  22267287   Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk.

  22351525   The role of TERT in colorectal carcinogenesis.

  22972951   Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status.

  23001564   Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.

  23050049   Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study.

  23050056   Genetic variation in telomere maintenance genes in relation to ovarian cancer survival.

  23136140   Genetic susceptibility loci for subtypes of breast cancer in an African American population.

  23267696   Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case-control study.

  23535731   Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

  23535824   Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

  23535825   Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.

  23536562   Genetic susceptibility to triple-negative breast cancer.

  23593120   Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.

  23629941   Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study.

  23900074   A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk.

  24025454   Hereditary breast cancer: ever more pieces to the polygenic puzzle.

  24244489   A common variant in the SIAH2 locus is associated with estrogen receptor-positive breast cancer in the Chinese Han population.

  24292274   A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

  24359602   Common breast cancer risk variants in the post-COGS era: a comprehensive review.

  24743323   Genetic predisposition to in situ and invasive lobular carcinoma of the breast.

  24771903   Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.

  24886216   Functional annotation signatures of disease susceptibility loci improve SNP association analysis.

  24895409   Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.

  24941967   Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.

  25027329   Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.

  25254308   Polymorphisms in the TERT gene are associated with lung cancer risk in the Chinese Han population.

  25255808   Additive interactions between susceptibility single-nucleotide polymorphisms identified in genome-wide association studies and breast cancer risk factors in the Breast and Prostate Cancer Cohort Consortium.

  25456381   Epidemiology, biology, and treatment of triple-negative breast cancer in women of African ancestry.

  25487306   Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk.

  25611573   Association of breast cancer risk loci with breast cancer survival.

  25738283   Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness.

  26053551   A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase.

  26070784   Genetic risk variants associated with in situ breast cancer.

  26143636   TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma.

  26157023   Strategies for fine-mapping complex traits.

  26294352   Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology.

  26320593   A single-nucleotide polymorphism of CCL21 rs951005 T>C is associated with susceptibility of polymyositis and such patients with interstitial lung disease in a Chinese Han population.

  26405224   Familial predisposition and genetic risk factors for lymphoma.

  26510858   Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

  26621837   Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.

  26799699   Variants in TERT influencing telomere length are associated with paranoid schizophrenia risk.

  26803517   Relationship between five GWAS-identified single nucleotide polymorphisms and female breast cancer in the Chinese Han population.

  26848776   A targeted genetic association study of epithelial ovarian cancer susceptibility.

  26884359   Genetic predisposition to ductal carcinoma in situ of the breast.

  27186328   Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality.

  27392074   The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

  27420401   A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer.

  27424552   Genomics era and complex disorders: Implications of GWAS with special reference to coronary artery disease, type 2 diabetes mellitus, and cancers.

  27432226   Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

  27708667   Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes.

  27759658   Genome-wide identification of expression quantitative trait loci for human telomerase.

  27814745   Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.

  27825120   Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.

  27825130   Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population.

  28057933   Polymorphisms in Telomere Length Associated TERC and TERT predispose for Ischemic Stroke in a Chinese Han population.

  28060765   Genetic polymorphisms in TERT are associated with increased risk of esophageal cancer.

  28098224   Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.

  28171663   Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer.

  28195142   A genome-wide association study yields five novel thyroid cancer risk loci.

  28233473   Genetic variants in telomere-maintenance genes are associated with ovarian cancer risk and outcome.

  28757654   Predicting Triple-Negative Breast Cancer Subtype Using Multiple Single Nucleotide Polymorphisms for Breast Cancer Risk and Several Variable Selection Methods.

  28978050   Association of TERT polymorphisms and risk of coronary heart disease in a Chinese Han population.

  29100352   Genetic variations in TERC and TERT genes are associated with renal cell carcinoma risk in a Chinese Han population.

  29299136   Genetic variations in TERC and TERT genes are associated with lung cancer risk in a Chinese Han population.

  29332343   Clinical relevance of telomerase polymorphism for breast cancer: A systematic review.

  29382703   Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.

  29445177   Validating a breast cancer score in Spanish women. The MCC-Spain study.

  29507683   Association of TERT polymorphisms with chronic hepatitis B in a Chinese Han population.

  29771920   Maternal human telomerase reverse transcriptase variants are associated with preterm labor and preterm premature rupture of membranes.

  30194396   Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.

  30249004   Epidemiology of Moderate Alcohol Consumption and Breast Cancer: Association or Causation?

  30285756   Subtype-specific associations between breast cancer risk polymorphisms and the survival of early-stage breast cancer.

  30900102   Genetic variations associated with telomere length confer risk of gastric cardia adenocarcinoma.

  31270965   TERT gene polymorphisms are associated with chronic obstructive pulmonary disease risk in the Chinese Li population.

  31454181   TERT rs10069690 polymorphism and cancers risk: A meta-analysis.

  31469255   A genome-wide association and replication study of blood pressure in Ugandan early adolescents.

  31538903   Association between hTERT Polymorphisms and Female Papillary Thyroid Carcinoma.

  31651569   Associations of telomerase reverse transcriptase rs10069690 and rs2736100 polymorphisms with papillary thyroid carcinoma.

  32487238   MassARRAY analysis of twelve cancer related SNPs in esophageal squamous cell carcinoma in J&K, India.

  32502020   Genetic variations associated with telomere length affect the risk of gastric carcinoma.

  32577134   Single nucleotide polymorphisms in telomere length-related genes are associated with hepatocellular carcinoma risk in the Chinese Han population.

  32577690   G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19.

  32742450   Identification of Leukocyte telomere length-related genetic variants contributing to predisposition of Esophageal Squamous Cell Carcinoma.

  33342785   Breast cancer-related single-nucleotide polymorphism and their risk contribution in Mexican women.

  33374413   Tracking the genetic susceptibility of B-cell non-Hodgkin's lymphomas based on genome-wide association studies.

  33718071   Association of TERT gene polymorphisms with clinical benign prostatic hyperplasia in a Chinese Han population of the Northwest region.

  33909215   Intron 4-5 hTERT DNA Hypermethylation in Merkel Cell Carcinoma: Frequency, Association with Other Clinico-pathological Features and Prognostic Relevance.

  33928715   Evaluation of 17 genetic variants in association with leukemia in the north Indian population using MassARRAY Sequenom.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

  35563554   Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer.

  35847915   Cumulative Evidence for Relationships Between Multiple Variants in the TERT and CLPTM1L Region and Risk of Cancer and Non-Cancer Disease.