Normal allele: TT
A break in the cannabinoid receptor gene CNR1 modulates the risk of addiction. Cannabis dependence may occur when CBD oil is ingested.
Polymorphism rs806368 is related to topics like this:
Research and publications:
17509535 CNR1 variation modulates risk for drug and alcohol dependence.
18213623 Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder.
18606954 Cannabinoid receptor 1 gene association with nicotine dependence.
19165169 Variants in the CNR1 and the FAAH genes and adiposity traits in the community.
19335651 Candidate genes for cannabis use disorders: findings, challenges and directions.
19886064 Involvement of CNR1 gene polymorphisms in modulating the effects of the endocannabinoid system.
21798285 Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors.
22085192 Cannabinoid receptor 1 gene is associated with alcohol dependence.
22567136 CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake.
23748922 A common functional promoter variant links CNR1 gene expression to HDL cholesterol level.
24180398 Endocannabinoid signaling in the etiology and treatment of major depressive illness.
25268406 Cannabinoid receptor gene polymorphisms and bone mineral density in Korean postmenopausal women.
25819021 A review of pharmacogenetic studies of substance-related disorders.
27034934 Uremic Pruritus Is Not Associated with Endocannabinoid Receptor 1 Gene Polymorphisms.
27642547 Genetic and Environmental Factors Associated with Cannabis Involvement.
28099629 The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data.
28534260 Pharmacogenetics of Cannabinoids.
30129173 Genetic polymorphisms of the endocannabinoid system in obesity and diabetes.
30845666 Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System.
31184938 CNR1 and FAAH variation and affective states induced by marijuana smoking.
32114795 Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder.
32481444 Precision therapeutic opioid dosing implications from genetic biomarkers and craving score.
34453125 Molecular genetics of cocaine use disorders in humans.
34566715 FAAH and CNR1 Polymorphisms in the Endocannabinoid System and Alcohol-Related Sleep Quality.
35140610 Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.
35327588 Biomarkers of the Endocannabinoid System in Substance Use Disorders.