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SNP information rs806368

RS806368

Normal allele: TT

A break in the cannabinoid receptor gene CNR1 modulates the risk of addiction. Cannabis dependence may occur when CBD oil is ingested.

Polymorphism rs806368 is related to topics like this:


Research and publications:

  17509535   CNR1 variation modulates risk for drug and alcohol dependence.

  18179391   Association between single nucleotide polymorphisms in the cannabinoid receptor gene (CNR1) and impulsivity in southwest California Indians.

  18213623   Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder.

  18606954   Cannabinoid receptor 1 gene association with nicotine dependence.

  18776593   Cannabinoid type-1 receptor gene polymorphisms are associated with central obesity in a Southern Brazilian population.

  19016476   Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.

  19018721   Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index.

  19052543   Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.

  19165169   Variants in the CNR1 and the FAAH genes and adiposity traits in the community.

  19335651   Candidate genes for cannabis use disorders: findings, challenges and directions.

  19886064   Involvement of CNR1 gene polymorphisms in modulating the effects of the endocannabinoid system.

  20010914   Association of polymorphisms of the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes with heroin addiction: impact of long repeats of CNR1.

  20415562   Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity.

  20838400   Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?

  21129839   A common variation in the cannabinoid 1 receptor (CNR1) gene is associated with pre-eclampsia in the Central European population.

  21420833   Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia.

  21633404   Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease.

  21695734   Cannabinoid type 1 receptor gene polymorphisms are not associated with olanzapine-induced weight gain.

  21711518   Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

  21790903   Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.

  21798285   Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors.

  22085192   Cannabinoid receptor 1 gene is associated with alcohol dependence.

  22123166   Contributions of endocannabinoid signaling to psychiatric disorders in humans: genetic and biochemical evidence.

  22567136   CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake.

  22669173   Associations between cannabinoid receptor-1 (CNR1) variation and hippocampus and amygdala volumes in heavy cannabis users.

  23407780   Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.

  23748922   A common functional promoter variant links CNR1 gene expression to HDL cholesterol level.

  23799528   Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies.

  24172113   Impulsivity, variation in the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes, and marijuana-related problems.

  24180398   Endocannabinoid signaling in the etiology and treatment of major depressive illness.

  24407958   Risky alcohol consumption in young people is associated with the fatty acid amide hydrolase gene polymorphism C385A and affective rating of drug pictures.

  25093427   Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome.

  25136364   Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controls.

  25268406   Cannabinoid receptor gene polymorphisms and bone mineral density in Korean postmenopausal women.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  26044620   Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

  26756393   Longitudinal predictors of cannabis use and dependence in offspring from families at ultra high risk for alcohol dependence and in control families.

  27034934   Uremic Pruritus Is Not Associated with Endocannabinoid Receptor 1 Gene Polymorphisms.

  27217270   Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis.

  27500453   Lifetime use of cannabis from longitudinal assessments, cannabinoid receptor (CNR1) variation, and reduced volume of the right anterior cingulate.

  27642547   Genetic and Environmental Factors Associated with Cannabis Involvement.

  28099629   The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data.

  28349993   Cannabinoid Receptor Type 1 and mu-Opioid Receptor Polymorphisms Are Associated With Cyclic Vomiting Syndrome.

  28534260   Pharmacogenetics of Cannabinoids.

  28930056   Developmentally Specific Associations Between CNR1 Genotype and Cannabis Use Across Emerging Adulthood.

  29963071   Detection of Significant Association Between Variants in Cannabinoid Receptor 1 Gene (CNR1) and Personality in African-American Population.

  30129173   Genetic polymorphisms of the endocannabinoid system in obesity and diabetes.

  30845666   Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System.

  31184938   CNR1 and FAAH variation and affective states induced by marijuana smoking.

  32114795   Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder.

  32272684   The Relationship Between Selected CNR1, MC4R, LEP, FTO and VDR Gene Polymorphisms and Several Basic Toxicological Parameters Among Persons Occupationally Exposed to Arsenic, Cadmium and Lead.

  32414087   Cannabis Constituents and Acetylcholinesterase Interaction: Molecular Docking, In Vitro Studies and Association with CNR1 rs806368 and ACHE rs17228602.

  32433545   Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and schizophrenia.

  32481444   Precision therapeutic opioid dosing implications from genetic biomarkers and craving score.

  33575982   Variability in cannabinoid receptor genes is associated with psychiatric comorbidities in anorexia nervosa.

  34355541   The associations of CNR1 SNPs and haplotypes with vulnerability and treatment response phenotypes in Han Chinese with major depressive disorder: A case-control association study.

  34453125   Molecular genetics of cocaine use disorders in humans.

  34566715   FAAH and CNR1 Polymorphisms in the Endocannabinoid System and Alcohol-Related Sleep Quality.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

  35327588   Biomarkers of the Endocannabinoid System in Substance Use Disorders.

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