Research and publications:
17786212 Heterogeneity in meta-analyses of genome-wide association investigations
17928989 Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.
17959933 Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population
18159244 Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
18162508 Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population
18224312 Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment
18251005 Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans.
18256137 Regulation of Fto/Ftm gene expression in mice and humans
18335027 Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP
18379722 Variations in the FTO gene are associated with severe obesity in the Japanese
18423522 Estimating odds ratios in genome scans: an approximate conditional likelihood approach
18426861 Association analysis of type 2 diabetes Loci in type 1 diabetes
18443202 Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies
18445669 Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity
18469204 Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
18487448 Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population
18535549 Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.
18591388 Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk
18599522 FTO variants are associated with obesity in the Chinese and Malay populations in Singapore
18689899 Exchangeable models of complex inherited diseases
18694974 Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study
18782870 Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008
18787525 FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women
18852197 Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants
18991055 Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.
19002430 Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population
19008344 Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians
19053021 Variation in the FTO gene influences food intake but not energy expenditure.
19056611 Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data
19074959 ATOM: a powerful gene-based association test by combining optimally weighted markers
19096518 A novel association of HK1 with glycated hemoglobin in a nondiabetic population: a genome-wide assessment of 14,618 Women's Genome Health Study participants.
19161620 An open access database of genome-wide association results
19207020 Meta-analysis in genome-wide association studies
19303973 RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.
19322589 Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study
19323962 Genome-wide association studies in type 2 diabetes
19341491 Genome-based prediction of common diseases: methodological considerations for future research
19373277 Validating, augmenting and refining genome-wide association signals
19401414 Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
19460916 Genetic architecture of type 2 diabetes: recent progress and clinical implications
19474294 Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
19478790 The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
19543202 FTO genotype is associated with exercise training-induced changes in body composition.
19553259 Common body mass index-associated variants confer risk of extreme obesity
19584900 Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany
19602701 Underlying genetic models of inheritance in established type 2 diabetes associations
19626703 Were genome-wide linkage studies a waste of time? Exploiting candidate regions within genome-wide association studies
19734549 Ranking of genome-wide association scan signals by different measures
19741467 Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.
19794065 Polygenic risk variants for type 2 diabetes susceptibility modify age at diagnosis in monogenic HNF1A diabetes
19798072 FTO genotype and the weight loss benefits of moderate intensity exercise.
19822564 Genetic Effects of FTO and MC4R Polymorphisms on Body Mass in Constitutional Types
19833889 Genetic heterogeneity in latent autoimmune diabetes is linked to various degrees of autoimmune activity: results from the Nord-Trøndelag Health Study
19862325 PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population
19931040 Simultaneous genotype calling and haplotype phasing improves genotype accuracy and reduces false-positive associations for genome-wide association studies
20009087 Genetic variation at the FTO locus influences RBL2 gene expression.
20017965 Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study.
20017978 Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study
20018066 Epistatic interactions of CDKN2B-TCF7L2 for risk of type 2 diabetes and of CDKN2B-JAZF1 for triglyceride/high-density lipoprotein ratio longitudinal change: evidence from the Framingham Heart Study
20049090 Association between type 2 diabetes loci and measures of fatness
20057365 Meta-analysis added power to identify variants in FTO associated with type 2 diabetes and obesity in the Asian population.
20061430 Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a chinese population.
20080751 Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.
20126254 Rare variants create synthetic genome-wide associations.
20127379 From monogenic to polygenic obesity: recent advances.
20142250 Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study
20144327 A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel
20161779 Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort
20203524 Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk
20299471 FTO genetic variation and association with obesity in West Africans and African Americans.
20337217 FTO polymorphisms are associated with obesity but not with diabetes in East Asian populations: a meta-analysis.
20362271 Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.
20377915 FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth.
20381893 The genetics of obesity: FTO leads the way.
20397748 Genome-wide association study of height and body mass index in Australian twin families.
20421936 Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.
20430937 Fine mapping of the association with obesity at the FTO locus in African-derived populations.
20442772 Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.
20502638 Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.
20509872 Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.
20512162 The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels.
20532014 The epidemiology of diabetes in Korea: from the economics to genetics.
20647405 No association between FTO or HHEX and endometrial cancer risk.
20694148 A genome-wide association study of the metabolic syndrome in Indian Asian men.
20712903 Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study
20725061 MC4R variant is associated with BMI but not response to resistance training in young females.
20805105 Synthetic associations in the context of genome-wide association scan signals
20816195 Analyses of shared genetic factors between asthma and obesity in children.
20858286 Variant rs9939609 in the FTO gene is associated with body mass index among Chinese children.
20862305 Identification of new genetic risk variants for type 2 diabetes.
20865176 Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups.
20886378 Physiologic characterization of type 2 diabetes-related loci
20935629 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
21036813 A variable selection method for genome-wide association studies.
21037115 Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.
21037323 Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.
21084393 Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects.
21091714 The genetics of type 2 diabetes: what have we learned from GWAS?
21102551 Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.
21103332 Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies
