SNP information rs7498665

Research and publications:

  17228025   The SH2B gene is associated with serum leptin and body fat in normal female twins.

  19079261   Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

  19164386   Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden.

  19478790   The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.

  19526209   Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

  19553259   Common body mass index-associated variants confer risk of extreme obesity

  19910641   Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus

  19910938   Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.

  20110568   Combined analyses of 20 common obesity susceptibility variants.

  20127379   From monogenic to polygenic obesity: recent advances.

  20369022   Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.

  20386550   Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.

  20397748   Genome-wide association study of height and body mass index in Australian twin families.

  20616199   Evaluation of genetic susceptibility loci for obesity in Chinese women.

  20712903   Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study

  20725061   MC4R variant is associated with BMI but not response to resistance training in young females.

  20816152   Obesity and diabetes genetic variants associated with gestational weight gain.

  20816195   Analyses of shared genetic factors between asthma and obesity in children.

  20824172   Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.

  20966902   Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.

  21267540   Genetic predisposition to obesity leads to increased risk of type 2 diabetes.

  21283731   FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome.

  21357383   No association of risk variants for diabetes and obesity with breast cancer: the Multiethnic Cohort and PAGE studies.

  21466928   Genetics and epigenetics of obesity.

  21750520   Implication of European-derived adiposity loci in African Americans.

  21773002   Mendelian Randomisation Study of Childhood BMI and Early Menarche.

  21907990   The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells.

  21912638   Studies of metabolic phenotypic correlates of 15 obesity associated gene variants.

  21976109   Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai Endometrial Cancer Genetics Study.

  22029802   Genetic risk score does not correlate with body mass index of Latina women in a clinical trial.

  22051089   Associations of obesity genes with obesity-related outcomes in multiethnic children.

  22083549   Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty.

  22384102   A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study.

  23270367   Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants.

  23339409   Reduced genetic influence on childhood obesity in small for gestational age children.

  23640704   Common variants near BDNF and SH2B1 show nominal evidence of association with snacking behavior in European populations.

  23712987   Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study.

  24278702   The complex interplay of genetic and lifestyle risk factors in type 2 diabetes: an overview.

  24392269   Gene-Lifestyle Interactions in Obesity.

  24528214   Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis.

  25126397   SH2B1 regulation of energy balance, body weight, and glucose metabolism.

  25269698   Obesity and the risk of adenocarcinoma of the esophagus and Barrett's esophagus: a Mendelian randomized trial.

  26075635   Exploring genetic markers of adult obesity risk in black adolescent South Africans-the Birth to Twenty Cohort.

  26263223   The Relationships of Obesity-Related Genetic Variants With Metabolic Profiles and Response to Metformin in Clozapine-Treated Patients With Schizophrenia.

  26480920   Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.

  26495240   Obesity-Related Genetic Variants and their Associations with Physical Activity.

  26543368   Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.

  26833246   New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

  27465381   Sugar-sweetened beverage consumption and genetic predisposition to obesity in 2 Swedish cohorts.

  28636007   Analysis of association of gene variants with obesity traits in New Zealand European children at 6 years of age.

  28661716   Gene-by-Activity Interactions on Obesity Traits of 6-Year-Old New Zealand European Children: A Children of SCOPE Study.

  28977211   Association of 5-HT2C (rs3813929) and UCP3 (rs1800849) gene polymorphisms with type 2 diabetes in obese women candidates for bariatric surgery.

  31754094   Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI.

  31884074   Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses.

  32228543   Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients.

  32492003   [The Role of Natural Selection in the Formation of the Genetic Structure of Populations by SNP Markers in Association with Body Mass Index and Obesity].

  33170161   Genetic test for the prescription of diets in support of physical activity.

  34556834   The genetics of obesity: from discovery to biology.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.