SNP information rs6457617

Research and publications:

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  19116921   Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region.

  19714643   TRAF1 polymorphisms associated with rheumatoid arthritis susceptibility in Asians and in Caucasians.

  19837788   Capture of type 1 diabetes-susceptible HLA DR-DQ haplotypes in Japanese subjects using a tag single nucleotide polymorphism.

  19846760   Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.

  20017963   Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.

  20018025   Genome-wide analysis of haplotype interaction for the data from the North American Rheumatoid Arthritis Consortium.

  20018049   Evaluation of an optimal receiver operating characteristic procedure.

  20018075   Genome-wide association study of rheumatoid arthritis by a score test based on wavelet transformation.

  20018081   Assessment of gene-covariate interactions by incorporating covariates into association mapping.

  20122189   Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso.

  20309765   Bagging optimal ROC curve method for predictive genetic tests, with an application for rheumatoid arthritis.

  20309874   Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.

  20362271   Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.

  20369022   Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.

  20383147   Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus.

  20426808   AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm.

  20546594   An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings.

  20549515   Genome-wide searching of rare genetic variants in WTCCC data.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21217814   Presymptomatic risk assessment for chronic non-communicable diseases.

  21595938   Polymorphisms associated with rheumatoid arthritis do not protect against Alzheimer's disease.

  21739420   Genetic variants in the HLA-DRB1 gene are associated with Kashin-Beck disease in the Tibetan population.

  21750679   Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis.

  21779181   Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.

  21804012   Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases.

  22102179   Genetics of systemic sclerosis: an update.

  22355377   Caucasian and Asian specific rheumatoid arthritis risk loci reveal limited replication and apparent allelic heterogeneity in north Indians.

  22615847   Association analysis of the extended MHC region in celiac disease implicates multiple independent susceptibility loci.

  22972380   Investigation of genetic risk factors for chronic adult diseases for association with preterm birth

  23025665   A meta-analysis of genome-wide association studies of follicular lymphoma.

  24449572   Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

  24931982   GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database.

  25616667   Genetic variants are major determinants of CSF antibody levels in multiple sclerosis.

  25893807   Persistent HPV16/18 infection in Indian women with the A-allele (rs6457617) of HLA-DQB1 and T-allele (rs16944) of IL-1β -511 is associated with development of cervical carcinoma.

  26106387   Pathogenesis of Systemic Sclerosis.

  26821282   Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance.

  27153677   Assessing statistical significance in multivariable genome wide association analysis.

  27812365   Shared Genetic Etiology of Autoimmune Diseases in Patients from a Biorepository Linked to De-identified Electronic Health Records.

  29168332   Associative role of HLA-DRB1 SNP genotypes as risk factors for susceptibility and severity of rheumatoid arthritis: A North-east Indian population-based study.

  29321349   Analysis of two susceptibility SNPs in HLA region and evidence of interaction between rs6457617 in HLA-DQB1 and HLA-DRB1*04 locus on Tunisian rheumatoid arthritis.