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SNP information rs6454674

RS6454674

Normal allele: TT

Variation in the cannabinoid receptor gene CNR1 increases the risk of cannabis dependence.

Polymorphism rs6454674 is related to topics like this:


Research and publications:

  16917946   Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents.

  17509535   CNR1 variation modulates risk for drug and alcohol dependence.

  17881126   No association of CNR1 gene variations with susceptibility to schizophrenia.

  18213623   Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder.

  18375449   Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations.

  18606954   Cannabinoid receptor 1 gene association with nicotine dependence.

  19016476   Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.

  19052543   Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.

  19335651   Candidate genes for cannabis use disorders: findings, challenges and directions.

  19443135   The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults.

  19886064   Involvement of CNR1 gene polymorphisms in modulating the effects of the endocannabinoid system.

  20010914   Association of polymorphisms of the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes with heroin addiction: impact of long repeats of CNR1.

  20549395   Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies

  20838400   Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?

  21480765   Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women.

  21711518   Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

  21714860   Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces.

  21790903   Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.

  21798285   Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors.

  21905019   Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia.

  22085192   Cannabinoid receptor 1 gene is associated with alcohol dependence.

  22123166   Contributions of endocannabinoid signaling to psychiatric disorders in humans: genetic and biochemical evidence.

  22669173   Associations between cannabinoid receptor-1 (CNR1) variation and hippocampus and amygdala volumes in heavy cannabis users.

  23422373   CNR1 gene and risk of the metabolic syndrome in patients with schizophrenia.

  24180398   Endocannabinoid signaling in the etiology and treatment of major depressive illness.

  24407958   Risky alcohol consumption in young people is associated with the fatty acid amide hydrolase gene polymorphism C385A and affective rating of drug pictures.

  25136364   Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controls.

  25477898   Replication of obesity and diabetes-related SNP associations in individuals from Yucatán, México.

  27034934   Uremic Pruritus Is Not Associated with Endocannabinoid Receptor 1 Gene Polymorphisms.

  27500453   Lifetime use of cannabis from longitudinal assessments, cannabinoid receptor (CNR1) variation, and reduced volume of the right anterior cingulate.

  27642547   Genetic and Environmental Factors Associated with Cannabis Involvement.

  28099629   The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data.

  28534260   Pharmacogenetics of Cannabinoids.

  30486733   Fibromyalgia: Genetics and epigenetics insights may provide the basis for the development of diagnostic biomarkers.

  30845666   Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System.

  33401515   On the Role of Central Type-1 Cannabinoid Receptor Gene Regulation in Food Intake and Eating Behaviors.

  34161225   A family-based study to identify genetic biomarkers for fibromyalgia: consideration of patient subgroups.

  34355541   The associations of CNR1 SNPs and haplotypes with vulnerability and treatment response phenotypes in Han Chinese with major depressive disorder: A case-control association study.

  34566715   FAAH and CNR1 Polymorphisms in the Endocannabinoid System and Alcohol-Related Sleep Quality.

  34786265   Diagnostic Challenges and Management of Fibromyalgia.

  35327588   Biomarkers of the Endocannabinoid System in Substance Use Disorders.

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