Normal allele: AA
Genetic polymorphisms involved in the insulin-like growth factor (IGF) pathway regulate mammographic breast density ratio.
Polymorphism rs6220 is related to topics like this:
Research and publications:
18064566 Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density.
18562769 Genetic variation in insulin-like growth factors and brain tumor risk.
18772892 Can genes for mammographic density inform cancer aetiology?
19784788 Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk.
20039319 IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort.
21552154 Common genetic variation in the IGF1 associates with maximal force output.
28315227 Insulin-like growth factor 1 gene polymorphism in women with breast cancer.
29172265 SNPs in the Insulin-Like Growth Factor Gene and Obesity Impact on Colorectal Cancer in Egyptians.