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SNP information rs6220


Normal allele: AA

Genetic polymorphisms involved in the insulin-like growth factor (IGF) pathway regulate mammographic breast density ratio.

Polymorphism rs6220 is related to topics like this:

INSR Gene Insulin Receptor

The gene known as INSR directs the production of insulin receptors - proteins present in various...

Research and publications:

  17911177   Implications for prostate cancer of insulin-like growth factor-I (IGF-I) genetic variation and circulating IGF-I levels.

  18064566   Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density.

  18199734   IGF-I and IGF-II genetic variation and breast cancer risk in Chinese women: results from the Shanghai Breast Cancer Study.

  18398029   Genetic polymorphisms involved in insulin-like growth factor (IGF) pathway in relation to mammographic breast density and IGF levels.

  18562769   Genetic variation in insulin-like growth factors and brain tumor risk.

  18772892   Can genes for mammographic density inform cancer aetiology?

  19784788   Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk.

  20039319   IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort.

  20302654   Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.

  20484221   A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians.

  20810604   Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer.

  20935157   Germline polymorphisms in genes involved in the IGF1 pathway predict efficacy of cetuximab in wild-type KRAS mCRC patients.

  21113804   IGF1 htSNPs in relation to IGF-1 levels in young women from high-risk breast cancer families: implications for early-onset breast cancer.

  21514219   Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

  21552154   Common genetic variation in the IGF1 associates with maximal force output.

  21791631   Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.

  21915365   Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.

  23180020   Association of a common genetic variant of the IGF-1 gene with event-free survival in patients with HER2-positive breast cancer.

  24895547   Double-bottom chaotic map particle swarm optimization based on chi-square test to determine gene-gene interactions.

  26738606   Insulin-like growth factor 1 receptor expression and IGF1R 3129G > T polymorphism are associated with response to neoadjuvant chemotherapy in breast cancer patients: results from the NEOZOTAC trial (BOOG 2010-01).

  28315227   Insulin-like growth factor 1 gene polymorphism in women with breast cancer.

  28369940   Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial.

  29172265   SNPs in the Insulin-Like Growth Factor Gene and Obesity Impact on Colorectal Cancer in Egyptians.

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