SNP information rs61764370

Research and publications:

  19834118   MicroRNAs: tools for cancer diagnostics

  20495573   Genetic variation in microRNA networks: the implications for cancer research

  20647319   A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk.

  20843204   MicroRNA binding site polymorphisms as biomarkers of cancer risk.

  21385923   The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.

  21636674   MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium.

  21692980   Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer

  21807336   Association between KRAS rs61764370 and triple-negative breast cancer--a false positive?

  22003074   KRAS rs61764370 in Epithelial Ovarian Cancer-Letter.

  22082760   MicroRNAs in mutagenesis, genomic instability, and DNA repair

  22166496   The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.

  22584434   High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease.

  23010532   No evidence for genetic association with the let-7 microRNA-binding site or other common KRAS variants in risk of endometriosis.

  23052130   A LIN28B polymorphism predicts for colon cancer survival.

  23586049   The role of microRNAs in cancer susceptibility.

  23614619   SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers.

  24282149   Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.

  24764666   MicroRNAs in colorectal cancer as markers and targets: Recent advances.

  25114582   MicroRNA binding site polymorphisms as biomarkers in cancer management and research.

  25183481   A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy.

  25940428   No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

  25987236   Functional variants in CYP1B1, KRAS and MTHFR genes are associated with shorter telomere length in postmenopausal women.

  26077004   Comparison of the prevalence of KRAS-LCS6 polymorphism (rs61764370) within different tumour types (colorectal, breast, non-small cell lung cancer and brain tumours). A study of the Czech population.

  26162609   Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial.

  26573509   Role of KRAS-LCS6 polymorphism in advanced NSCLC patients treated with erlotinib or docetaxel in second line treatment (TAILOR).

  26909137   Evaluation of antibody-dependent cell-mediated cytotoxicity activity and cetuximab response in KRAS wild-type metastatic colorectal cancer patients.

  27834829   MiRNAs and miRNA Polymorphisms Modify Drug Response.

  27853382   Genetic variation rs7930 in the miR-4273-5p target site is associated with a risk of colorectal cancer.

  27897268   Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis.

  27992614   A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men.

  28610418   KRAS Gene Polymorphisms and their Impact on Breast Cancer Risk in an Iranian Population.

  29048575   MicroRNA-binding site polymorphisms in genes involved in colorectal cancer etiopathogenesis and their impact on disease prognosis.

  31637880   MicroRNA-binding site polymorphisms and risk of colorectal cancer: A systematic review and meta-analysis.

  32823908   Critical Analysis of Genome-Wide Association Studies: Triple Negative Breast Cancer Quae Exempli Causa.

  33402978   Association of Rs61764370 polymorphism within let-7 microRNA-binding site with lung cancer in Iranian population.

  34787849   Association between rs61764370, rs9266, and rs140080026 polymorphisms of the KRAS gene and breast cancer risk in a Mexican population.

  35891756   Evaluation of the Role of the KRAS Gene Polymorphism LCS6 (rs61764370) in Iraqi Women with Ovarian Cancer.