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SNP information rs5569

Normal allele: GG

A polymorphism of the noradrenaline transporter gene (SLC6A2) is associated with attention deficit hyperactivity disorder.

Polymorphism rs5569 is related to topics like this:

ADHD, a behavioral disorder that usually commences during childhood, is marked by a brief attention...


Research and publications:

  17630229   Norepinephrine transporter polymorphisms T-182C and G1287A are not associated with alcohol dependence and its clinical subgroups.

  17917281   No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population.

  17994190   Norepinephrine transporter and catecholamine-O-methyltransferase gene variants and attention-deficit/hyperactivity disorder symptoms in adults

  18081710   Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression.

  18180394   Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans

  18779921   The combined effect of norepinephrine transporter gene and negative life events in major depression of Chinese Han population.

  18821566   SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.

  18937309   Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study.

  19693267   Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.

  19698724   Novel and functional norepinephrine transporter protein variants identified in attention-deficit hyperactivity disorder.

  19727679   Further evidence of association between amphetamine response and SLC6A2 gene variants.

  20008943   Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.

  20863575   Lack of association between response of OROS-methylphenidate and norepinephrine transporter (SLC6A2) polymorphism in Korean ADHD.

  21172166   Pharmacogenetics of antidepressant response.

  21368917   Epistasis between neurochemical gene polymorphisms and risk for ADHD.

  21527290   Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood.

  21687501   Pharmacogenetics of antidepressants.

  21992066   Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers.

  22105624   The genetics of attention deficit/hyperactivity disorder in adults, a review.

  22591463   Possible effect of norepinephrine transporter polymorphisms on methylphenidate-induced changes in neuropsychological function in attention-deficit hyperactivity disorder.

  22727709   Evaluation of genetic models for response in a randomized clinical trial of duloxetine in major depressive disorder.

  23185385   Comprehensive phenotype/genotype analyses of the norepinephrine transporter gene (SLC6A2) in ADHD: relation to maternal smoking during pregnancy.

  23442739   Psychomotor depressive symptoms may differentially respond to venlafaxine.

  23648227   Association between major depressive disorder and the norepinephrine transporter polymorphisms T-182C and G1287A: a meta-analysis.

  23733030   Pharmacogenetics in major depression: a comprehensive meta-analysis.

  24319431   Mechanisms of antidepressant resistance.

  24655776   Association between norepinephrine transporter gene (SLC6A2) polymorphisms and suicide in patients with major depressive disorder.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  25912538   Effects of persisting emotional impact from child abuse and norepinephrine transporter genetic variation on antidepressant efficacy in major depression: a pilot study.

  26746237   Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children.

  26832728   Genotyping of single nucleotide polymorphisms related to attention-deficit hyperactivity disorder.

  27521242   TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs.

  29230023   Pharmacogenetics predictors of methylphenidate efficacy in childhood ADHD.

  29374517   Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients.

  29431473   Genetic Association of the Norepinephrine Transporter Gene G1287A Polymorphism with Risk of Schizophrenia: A Case-Control Study and Meta-Analysis.

  29576985   Influence of allelic variations in relation to norepinephrine and mineralocorticoid receptors on psychopathic traits: a pilot study.

  29703117   Association between T-182C, G1287A polymorphism in NET gene and suicidality in major depressive disorder in Chinese patients.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30292339   Meta-analysis on the Association Between Norepinephrine Transporter Gene rs2242446, rs5569 Polymorphisms and Risk of Major Depressive Disorder.

  31377977   Association of endothelial nitric oxide synthase (eNOS) and norepinephrine transporter (NET) genes polymorphism with type 2 diabetes mellitus.

  32459709   The association between polymorphism of norepinephrine transporter G1287A and major depressive disorder, antidepressant response: a meta-analysis.

  32797194   Genetic Variation and Hot Flashes: A Systematic Review.

  33340618   Association between genetic variants of the norepinephrine transporter gene (SLC6A2) and bipolar I disorder.

  34797323   Noradrenergic genes polymorphisms and response to methylphenidate in children with ADHD: A systematic review and meta-analysis.

Numerous gastrointestinal disorders exhibit an inherited nature or entail a genetic predisposition...

Health conditions that alter a person's thoughts, emotions, and behaviors are referred to as mental...

An elaborate web of electrical signals is created by the brain and nervous system, which work...

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