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SNP information rs5029937

RS5029937

Normal allele: GG

The single nucleotide polymorphism rs5029937 in the TNFAIP3 gene correlates with the risk of rheumatoid arthritis.

Polymorphism rs5029937 is related to topics like this:

Is rheumatoid arthritis genetic

Chronic abnormal inflammation is the hallmark of rheumatoid arthritis, a disease that primarily...


Research and publications:

  19387456   Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.

  19417005   Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

  19838195   A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

  20075733   Recent advances in the genetics of rheumatoid arthritis.

  20219786   The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.

  20444755   Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.

  20453842   Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

  20461788   Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients.

  20498205   Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.

  20510233   Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20822710   Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis.

  20852893   Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.

  21068098   Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

  21336280   Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.

  22087647   Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population.

  22328738   Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.

  22355377   Caucasian and Asian specific rheumatoid arthritis risk loci reveal limited replication and apparent allelic heterogeneity in north Indians.

  22661644   Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.

  22770979   Presence of multiple independent effects in risk loci of common complex human diseases.

  22798268   Rheumatoid arthritis-associated polymorphisms at 6q23 are associated with radiological damage in autoantibody-positive RA.

  23121884   Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.

  24068971   Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

  24489017   TNFAIP3 gene polymorphisms associated with differential susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Korean population.

  26143186   Characteristics of A20 gene polymorphisms and clinical significance in patients with rheumatoid arthritis.

  26663301   Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

  27092776   A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

  27726311   Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus risk: an updated meta-analysis.

  28199970   Three single nucleotide polymorphisms of TNFAIP3 gene increase the risk of rheumatoid arthritis.

  28296250   Different genetic alteration of A20 in a Sézary syndrome case with Vα2-Jα22 T cell clone.

  28888761   Associations Between TNFAIP3 Gene Polymorphisms and Rheumatoid Arthritis Risk: A Meta-analysis.

  31217170   Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.

  34268230   Single nucleotide polymorphism rs5029937 in TNFAIP3 gene is correlated with risk of rheumatoid arthritis.

  36096187   HFE hemochromatosis in African Americans: Prevalence estimates of iron overload and iron overload-related disease.

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