SNP information rs5015480

Research and publications:

  17786212   Heterogeneity in meta-analyses of genome-wide association investigations

  17928989   Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

  18426861   Association analysis of type 2 diabetes Loci in type 1 diabetes

  18443202   Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies

  18469204   Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians

  18633108   Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

  19002430   Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population

  19056611   Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data

  19207020   Meta-analysis in genome-wide association studies

  19323962   Genome-wide association studies in type 2 diabetes

  19526209   Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

  19602701   Underlying genetic models of inheritance in established type 2 diabetes associations

  19622614   HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes.

  19734549   Ranking of genome-wide association scan signals by different measures

  19741166   Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study

  19741467   Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.

  19794065   Polygenic risk variants for type 2 diabetes susceptibility modify age at diagnosis in monogenic HNF1A diabetes

  19931040   Simultaneous genotype calling and haplotype phasing improves genotype accuracy and reduces false-positive associations for genome-wide association studies

  20017978   Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study

  20018041   The effect of multiple genetic variants in predicting the risk of type 2 diabetes

  20126254   Rare variants create synthetic genome-wide associations.

  20144327   A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel

  20460429   BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1.

  20503258   Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City.

  20509872   Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.

  20532014   The epidemiology of diabetes in Korea: from the economics to genetics.

  20550665   Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population.

  20581827   Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20862305   Identification of new genetic risk variants for type 2 diabetes.

  20886378   Physiologic characterization of type 2 diabetes-related loci

  20979565   Population structure of Aggarwals of north India as revealed by molecular markers.

  21084393   Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects.

  21103332   Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies

  21217814   Presymptomatic risk assessment for chronic non-communicable diseases.

  21368910   Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender.

  21444075   Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome.

  21490949   Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.

  21533175   Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.

  22038522   Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolism

  22052079   Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.

  22113416   Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study

  22233651   A genome-wide association study of gestational diabetes mellitus in Korean women

  22307069   Association of type 2 diabetes susceptibility loci with one-year weight loss in the look AHEAD clinical trial

  22377712   Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

  22506066   Genetic variants of IDE-KIF11-HHEX at 10q23.33 associated with type 2 diabetes risk: a fine-mapping study in Chinese population.

  22529894   Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

  22558147   Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes.

  22971100   Quick, "imputation-free" meta-analysis with proxy-SNPs.

  23166797   Hematopoietically-expressed homeobox gene three widely-evaluated polymorphisms and risk for diabetes: a meta-analysis.

  23185337   Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.

  23298195   Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk and diabetic nephropathy in the Chinese She population.

  23349771   Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.

  23462794   Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

  24112421   CDKAL1 and HHEX are associated with traits of type 2 diabetes in Yupik people.

  24520337   Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: the Singapore Chinese health study.

  24843659   Insights into the genetic basis of type 2 diabetes.

  25369983   Association between maternal single nucleotide polymorphisms in genes regulating glucose metabolism and risk for neural tube defects in offspring.

  25587982   Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study.

  25774817   Genetics of type 2 diabetes-pitfalls and possibilities.

  26240488   Utilizing Genetic Predisposition Score in Predicting Risk of Type 2 Diabetes Mellitus Incidence: A Community-based Cohort Study on Middle-aged Koreans.

  26789123   A HuGE Review and Meta-Analyses of Genetic Associations in New Onset Diabetes after Kidney Transplantation.

  27383215   Type 2 Diabetes Risk Allele Loci in the Qatari Population.

  27424552   Genomics era and complex disorders: Implications of GWAS with special reference to coronary artery disease, type 2 diabetes mellitus, and cancers.

  28067832   Type 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms.

  28738793   Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study.

  29720110   Effect of smoking on the association of HHEX (rs5015480) with diabetes among Korean women and heavy smoking men.

  30207601   Alcohol Intake Interacts with CDKAL1, HHEX, and OAS3 Genetic Variants, Associated with the Risk of Type 2 Diabetes by Lowering Insulin Secretion in Korean Adults.

  31237015   HHEX gene polymorphisms and type 2 diabetes mellitus: A case-control report from Iran.

  31299695   Common Type 2 Diabetes Genetic Risk Variants Improve the Prediction of Gestational Diabetes.

  32195947   The association between HHEX single-nucleotide polymorphism rs5015480 and gestational diabetes mellitus: A meta-analysis.

  33447064   Association Between Single Nucleotide Polymorphisms in CDKAL1 and HHEX and Type 2 Diabetes in Chinese Population.

  35450164   Pathophysiological Role of Genetic Factors Associated With Gestational Diabetes Mellitus.

  35456451   Gene-Environment Interaction on Type 2 Diabetes Risk among Chinese Adults Born in Early 1960s.