SNP information rs4950928

Research and publications:

  17160890   Functional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia.

  18403759   Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.

  18767121   Failure to confirm genetic association of the CHI3L1 gene with schizophrenia in Japanese and Chinese populations.

  19264973   Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.

  19336781   Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes.

  19421404   Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.

  19568425   Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.

  20051317   The chitinase 3-like 1 gene and schizophrenia: evidence from a multi-center case-control study and meta-analysis.

  20300754   Lack of evidence for association of two functional SNPs of CHI3L1 gene (HC-gp39) with rheumatoid arthritis.

  21257319   Genetic polymorphisms in chitinase 3-like 1 (CHI3L1) are associated with circulating YKL-40 levels, but not with angiographic coronary artery disease in a Chinese population.

  21530869   The CHI3L1 rs4950928 polymorphism is associated with asthma-related hospital admissions in children and young adults.

  21714862   Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects.

  21949714   The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease.

  22103814   YKL-40 genetic polymorphisms and the risk of liver disease progression in patients with advanced fibrosis due to chronic hepatitis C.

  22183936   Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis.

  22200767   Genetic association between human chitinases and lung function in COPD.

  22366530   A promoter variant in the chitinase 3-like 1 gene is associated with serum YKL-40 level and personality trait.

  22937056   Variations of CHI3L1, levels of the encoded glycoprotein YKL-40 and prediction of fatal and non-fatal ischemic stroke.

  22989351   YKL-40-gene polymorphism affects acute cellular rejection and fibrosis progression after transplantation for hepatitis C virus-induced liver disease.

  23071724   The Association between genetic variations of CHI3L1, levels of the encoded glycoprotein YKL-40 and the lipid profile in a Danish population.

  23190377   Association of CHI3L1 in African-Americans with prior history of asthma exacerbations and stress.

  23628340   The chitinase-like protein YKL-40: a possible biomarker of inflammation and airway remodeling in severe pediatric asthma.

  23706599   Plasma YKL-40 and CHI3L1 in systemic inflammation and sepsis-experience from two prospective cohorts.

  25203433   Correlation of chitinase 3-like 1 single nucleotide polymorphisms and haplotypes with uterine cervical cancer in Taiwanese women.

  25225167   YKL-40 and alcoholic liver and pancreas damage and disease in 86,258 individuals from the general population: cohort and mendelian randomization studies.

  25592985   Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40.

  25624368   Elevated plasma YKL-40, lipids and lipoproteins, and ischemic vascular disease in the general population.

  26095694   Observational and genetic plasma YKL-40 and cancer in 96,099 individuals from the general population.

  26372680   Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease.

  26779637   Are SMAD7 rs4939827 and CHI3L1 rs4950928 polymorphisms associated with colorectal cancer in Egyptian patients?

  26931462   Integrated analyses of gene expression and genetic association studies in a founder population.

  26986948   An Interleukin 13 Polymorphism Is Associated with Symptom Severity in Adult Subjects with Ever Asthma.

  26988593   Observationally and Genetically High YKL-40 and Risk of Venous Thromboembolism in the General Population: Cohort and Mendelian Randomization Studies.

  27193312   CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development.

  27732738   A longitudinal assessment of circulating YKL-40 levels in preschool children with wheeze.

  28260989   Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms with Hepatocellular Carcinoma in Taiwan.

  28293925   Genetic Signatures of Asthma Exacerbation.

  28681574   SPINK5 is associated with early-onset and CHI3L1 with late-onset atopic dermatitis.

  28739286   Genetic and epigenetic regulation of YKL-40 in childhood.

  29233108   Association between risk of asthma and gene polymorphisms in CHI3L1 and CHIA: a systematic meta-analysis.

  29618952   Role of genetic variations of chitinase 3-like 1 in bronchial asthmatic patients.

  30309792   Association of SNP-SNP Interactions Between RANKL, OPG, CHI3L1, and VDR Genes With Breast Cancer Risk in Egyptian Women.

  30341592   Functional variant of CHI3L1 gene is associated with neck metastasis in oral cancer.

  30988078   Functional study of the association of CHI3L1 polymorphisms with asthma susceptibility in the Southwest Chinese Han population.

  31295039   A genetic variation in CHI3L1 is associated with bronchial asthma.

  31563729   Measured and genetically predicted plasma YKL-40 levels and melanoma mortality.

  31972315   Elevated plasma YKL-40 and risk of infectious disease: a prospective study of 94665 individuals from the general population.

  32363159   Systemic Immune Modulation in Gliomas: Prognostic Value of Plasma IL-6, YKL-40, and Genetic Variation in YKL-40.

  32367614   Chitinase 3-like 1 polymorphisms and risk of chronic obstructive pulmonary disease and asthma in a Chinese population.

  33280245   Association of CHI3L1 gene variants with YKL-40 levels and hypertension incidence: A population-based nested case-control study in China.

  33622872   Significant Association of Chitinase 3-like 1 Genotypes to Asthma Risk in Taiwan.

  33659210   A Review of Cancer Genetics and Genomics Studies in Africa.

  35340006   Assessment of the Association between Genetic Polymorphisms in the CHI3L1 Gene and Asthma Risk.