SNP information rs4925386

Research and publications:

  20972440   Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.

  21655089   Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.

  21761138   Meta-analysis of new genome-wide association studies of colorectal cancer risk.

  22045029   Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.

  22363440   cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

  22629442   Evaluation of allele-specific somatic changes of genome-wide association study susceptibility alleles in human colorectal cancers.

  22675446   Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.

  22879968   Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.

  22999960   Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

  23300701   Genome-wide search for gene-gene interactions in colorectal cancer.

  23350875   A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  24587672   New genes emerging for colorectal cancer predisposition.

  24705330   Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  24801760   Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.

  24994789   Gene-environment interaction involving recently identified colorectal cancer susceptibility Loci.

  26078566   Association of colorectal cancer susceptibility variants with esophageal cancer in a Chinese population.

  26880076   Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers.

  26940994   GWASeq: targeted re-sequencing follow up to GWAS.

  26968355   Association of the Laminin, Alpha 5 (LAMA5) rs4925386 with height and longevity in an elderly population from Southern Italy.

  27078840   Genetic Variants Associated with Colorectal Adenoma Susceptibility.

  27146020   Colorectal cancer risk genes are functionally enriched in regulatory pathways.

  27313952   The Impact of Evolutionary Driving Forces on Human Complex Diseases: A Population Genetics Approach.

  27379672   Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.

  27437086   Allele Frequencies of the Single Nucleotide Polymorphisms Related to the Body Burden of Heavy Metals in the Korean Population and Their Ethnic Differences.

  28084440   Common risk variants for colorectal cancer: an evaluation of associations with age at cancer onset.

  28233817   Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study.

  28302063   Epigenetic and genetic alterations and their influence on gene regulation in chronic lymphocytic leukemia.

  29119627   Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery.

  29147930   SNP association study in PMS2-associated Lynch syndrome.

  29547645   Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population.