SNP information rs4779584

Research and publications:

  18084292   Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk.

  19011631   Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

  19786869   Recent insights into the pathogenesis of colorectal cancer.

  19843678   Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.

  20368424   Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition.

  20407467   Genome-wide linkage analyses of hereditary prostate cancer families with colon cancer provide further evidence for a susceptibility locus on 15q11-q14.

  20437058   The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.

  20501757   Low-penetrance susceptibility variants in familial colorectal cancer.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20585100   Genome-wide association studies of cancer.

  20628028   Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis.

  20648012   Association studies on 11 published colorectal cancer risk loci.

  20659471   Genetic heterogeneity in colorectal cancer associations between African and European americans.

  21071539   Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.

  21097774   Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome.

  21119214   Colorectal cancer susceptibility loci in a population-based study: Associations with morphological parameters.

  21179028   Replication study of SNP associations for colorectal cancer in Hong Kong Chinese.

  21314996   Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci.

  21357381   Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study.

  21402474   GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis.

  21655089   Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.

  21761138   Meta-analysis of new genome-wide association studies of colorectal cancer risk.

  22045029   Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.

  22235025   Susceptibility genetic variants associated with early-onset colorectal cancer.

  22363440   cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

  22367214   Characterization of gene-environment interactions for colorectal cancer susceptibility loci.

  22532847   Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population.

  22629442   Evaluation of allele-specific somatic changes of genome-wide association study susceptibility alleles in human colorectal cancers.

  22675446   Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.

  22848671   Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

  22879968   Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.

  22999960   Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

  23300701   Genome-wide search for gene-gene interactions in colorectal cancer.

  23350875   A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.

  23434150   Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

  23875689   Colorectal cancer-susceptibility single-nucleotide polymorphisms in Korean population.

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  24253443   Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis.

  24587672   New genes emerging for colorectal cancer predisposition.

  24705330   Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery.

  24727911   Germline variation in colorectal risk Loci does not influence treatment effect or survival in metastatic colorectal cancer.

  24753543   Shared and independent colorectal cancer risk alleles in TGFβ-related genes in African and European Americans.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  24801760   Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.

  24968322   Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.

  25117299   Cumulative effects of genetic markers and the detection of advanced colorectal neoplasias by population screening.

  25475391   Common genetic variants (rs4779584 and rs10318) at 15q13.3 contributes to colorectal adenoma and colorectal cancer susceptibility: evidence based on 22 studies.

  25873010   Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk.

  25956580   A colorectal cancer prediction model using traditional and genetic risk scores in Koreans.

  26078566   Association of colorectal cancer susceptibility variants with esophageal cancer in a Chinese population.

  26493165   GREM1 and POLE variants in hereditary colorectal cancer syndromes.

  26637073   A risk prediction model for colorectal cancer using genome-wide association study-identified polymorphisms and established risk factors among Japanese: results from two independent case-control studies.

  26880076   Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers.

  26940994   GWASeq: targeted re-sequencing follow up to GWAS.

  27078840   Genetic Variants Associated with Colorectal Adenoma Susceptibility.

  27146020   Colorectal cancer risk genes are functionally enriched in regulatory pathways.

  27280978   Explaining the disease phenotype of intergenic SNP through predicted long range regulation.

  27379672   Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.

  27630819   Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data.

  27766137   Epidemiology of colorectal cancer.

  28084440   Common risk variants for colorectal cancer: an evaluation of associations with age at cancer onset.

  28849422   The more from East-Asian, the better: risk prediction of colorectal cancer risk by GWAS-identified SNPs among Japanese.

  29547645   Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population.

  30337837   Single nucleotide polymorphisms and sporadic colorectal cancer susceptibility: a field synopsis and meta-analysis.

  31038671   Colorectal cancer susceptibility variants and risk of conventional adenomas and serrated polyps: results from three cohort studies.

  32022527   Synchronous and multiple renal cell carcinoma, clear cell and papillary: An approach to clinically significant genetic abnormalities.

  32170005   Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.

  32213001   UEG Week 2019 Poster Presentations.

  33976257   Genetic risk factors for colorectal cancer in multiethnic Indonesians.