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SNP information rs4765905

RS4765905

Normal allele: GG

A polymorphism of the potential-dependent calcium channel gene CACNA1C, is associated with risk of bipolar disorder, schizophrenia and other psychiatric disorders.

Polymorphism rs4765905 is related to topics like this:

Calcium score report

Our DNA health analysis detects a number of genetic polymorphisms associated with metabolic...

Research and publications:

  20723887   Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans.

  21926974   Genome-wide association study identifies five new schizophrenia loci.

  23025490   Ankyrin 3: genetic association with bipolar disorder and relevance to disease pathophysiology.

  23637625   Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.

  24174267   A population-based study of genetic variation and psychotic experiences in adolescents.

  24275578   MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese.

  24339136   Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants.

  24461634   Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia.

  24718684   Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence?

  26204268   Schizophrenia Related Variants in CACNA1C also Confer Risk of Autism.

  26276307   Meta-analysis of data from the Psychiatric Genomics Consortium and additional samples supports association of CACNA1C with risk for schizophrenia.

  27260792   Common variants in CACNA1C and MDD susceptibility: A comprehensive meta-analysis.

  27271857   CACNA1C hypermethylation is associated with bipolar disorder.

  27276213   Functional Characterization of Schizophrenia-Associated Variation in CACNA1C.

  29042896   Genome-Wide Supported Risk Variants in MIR137, CACNA1C, CSMD1, DRD2, and GRM3 Contribute to Schizophrenia Susceptibility in Pakistani Population.

  29599094   Replication of GWAS identified miR-137 and its target gene polymorphisms in Schizophrenia of South Indian population and meta-analysis with Psychiatric Genomics Consortium.

  31334289   Association Study of Sequence Variants in Voltage-gated Ca2+ Channel Subunit Alpha-1C and Autism Spectrum Disorders.

  32770953   The genome-wide supported CACNA1C gene polymorphisms and the risk of schizophrenia: an updated meta-analysis.

  35221147   Further evidence and meta-analysis support association of a single nucleotide polymorphism rs4765905 in CACNA1C with schizophrenia.

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