SNP information rs4464148

Research and publications:

  19155440   Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.

  19357349   Association of common genetic variants in SMAD7 and risk of colon cancer.

  19395656   The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression.

  20124488   Increased risk of colon cancer associated with a genetic polymorphism of SMAD7.

  21036793   Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field

  21060895   Identification of candidate genes for dyslexia susceptibility on chromosome 18.

  21068203   Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk.

  21075068   SMAD7 and MGMT genotype variants and cancer incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study.

  21088106   Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway.

  21097774   Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome.

  21179028   Replication study of SNP associations for colorectal cancer in Hong Kong Chinese.

  21221812   A risk-associated single nucleotide polymorphism of SMAD7 is common to colorectal, gastric, and lung cancers in a Han Chinese population.

  21387313   Genetic variation in bone morphogenetic protein and colon and rectal cancer.

  21910156   Common colorectal cancer risk variants in SMAD7 are associated with survival among prediagnostic nonsteroidal anti-inflammatory drug users: a population-based study of postmenopausal women.

  22554650   Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil.

  22848671   Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

  24212777   Predictive and prognostic factors in colorectal cancer: a personalized approach.

  24448986   Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.

  24727911   Germline variation in colorectal risk Loci does not influence treatment effect or survival in metastatic colorectal cancer.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  24941225   Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.

  28070019   SMAD7 polymorphisms and colorectal cancer risk: a meta-analysis of case-control studies.

  29119627   Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery.

  30337837   Single nucleotide polymorphisms and sporadic colorectal cancer susceptibility: a field synopsis and meta-analysis.

  31818908   Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

  32581566   Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review.

  33512737   A case-control study examining the association of smad7 and TLR single nucleotide polymorphisms on the risk of colorectal cancer in ulcerative colitis.