SNP information rs4245739

Research and publications:

  18279506   Mutation analysis of the MDM4 gene in German breast cancer patients.

  22870278   MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame.

  22916154   Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma.

  23173617   MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

  23536562   Genetic susceptibility to triple-negative breast cancer.

  23586049   The role of microRNAs in cancer susceptibility.

  23793604   Functional MDM4 rs4245739 genetic variant, alone and in combination with P53 Arg72Pro polymorphism, contributes to breast cancer susceptibility.

  24025454   Hereditary breast cancer: ever more pieces to the polygenic puzzle.

  24359602   Common breast cancer risk variants in the post-COGS era: a comprehensive review.

  24497837   Comprehensive functional annotation of 77 prostate cancer risk loci.

  24629096   mrSNP: software to detect SNP effects on microRNA binding.

  24654968   Germline genetics of the p53 pathway affect longevity in a gender specific manner.

  24771903   Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.

  25114582   MicroRNA binding site polymorphisms as biomarkers in cancer management and research.

  25203442   The functional TP53 rs1042522 and MDM4 rs4245739 genetic variants contribute to Non-Hodgkin lymphoma risk.

  25560306   Known susceptibility SNPs for sporadic prostate cancer show a similar association with "hereditary" prostate cancer.

  25670033   A genetic variant of MDM4 influences regulation by multiple microRNAs in prostate cancer.

  26025378   Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.

  26274820   A Regulatory MDM4 Genetic Variant Locating in the Binding Sequence of Multiple MicroRNAs Contributes to Susceptibility of Small Cell Lung Cancer.

  26471763   MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk.

  26496489   Altered Gene Expression Associated with microRNA Binding Site Polymorphisms.

  26510858   Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

  26867771   The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer.

  26979803   Chromatin interactions and candidate genes at ten prostate cancer risk loci.

  27070714   Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.

  27117709   Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

  27222754   Association between single nucleotide polymorphism in miR-499, miR-196a2, miR-146a and miR-149 and prostate cancer risk in a sample of Iranian population.

  27392074   The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

  27432226   Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

  27825120   Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.

  27834829   MiRNAs and miRNA Polymorphisms Modify Drug Response.

  28152060   Expression Quantitative Trait loci (QTL) in tumor adjacent normal breast tissue and breast tumor tissue.

  28158999   MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk.

  28164646   Analysis of the Association between MDM4 rs4245739 Single Nucleotide Polymorphism and Breast Cancer Susceptibility.

  28547953   Lack of Associations of the MDM4 rs4245739 Polymorphism with Risk of Thyroid Cancer among Iranian-Azeri Patients: a Case-Control Study.

  28561882   MUC1 rs4072037 polymorphism is associated with decreased risk of gastric cancer: a meta-analysis.

  28924212   CHST9 rs1436904 genetic variant contributes to prognosis of triple-negative breast cancer.

  29101112   Prostate Cancer Germline Variations and Implications for Screening and Treatment.

  29372105   Profile of the breast cancer susceptibility marker rs4245739 identifies a role for miRNAs.

  29382703   Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.

  29439926   Association of Single Nucleotide Polymorphisms of the MDM4 Gene With the Susceptibility to Breast Cancer in a Southeast Iranian Population Sample.

  29445177   Validating a breast cancer score in Spanish women. The MCC-Spain study.

  29892050   Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

  30594178   A genome wide SNP genotyping study in the Tunisian population: specific reporting on a subset of common breast cancer risk loci.

  30956778   Specific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients.

  31637880   MicroRNA-binding site polymorphisms and risk of colorectal cancer: A systematic review and meta-analysis.

  32492903   Association Analysis of TP53 rs1042522, MDM2 rs2279744, rs3730485, MDM4 rs4245739 Variants and Acute Myeloid Leukemia Susceptibility, Risk Stratification Scores, and Clinical Features: An Exploratory Study.

  32556890   Association of KLK3, VAMP8 and MDM4 Genetic Variants within microRNA Binding Sites with Prostate Cancer: Evidence from Serbian Population.

  32823908   Critical Analysis of Genome-Wide Association Studies: Triple Negative Breast Cancer Quae Exempli Causa.

  33273845   Association of MDM4 Gene rs4245739 Polymorphism with the Risk and Clinical Characteristics of Colorectal Cancer in a Chinese Han Population.

  33669778   Associations of MDM2 and MDM4 Polymorphisms with Early-Stage Breast Cancer.

  34077778   Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis.

  34347554   Five MDM4 gene polymorphisms on cancer risk: An updated systematic review and meta-analysis.

  35098683   MDM4 polymorphisms associated with the risk but not the prognosis of esophageal cancer in Cixian high-incidence region from northern China.

  35347102   The Correlation of Mouse Double Minute 4 (MDM4) Polymorphisms (rs4245739, rs1563828, rs11801299, rs10900598, and rs1380576) with Cancer Susceptibility: A Meta-Analysis.