Upload the DNA data file of the test

23andMe, AncestryDNA, FamilyTreeDNA, MyHeritage

and get an enhanced
personalized health report
free without registration

Files accepted .txt, .csv, .zip, .csv.gz

File data is not stored on the server

SNP information rs3800373

RS3800373

Normal allele: AA

FKBP5 polymorphisms increase symptoms of PTSD and anxiety.

Polymorphism rs3800373 is related to topics like this:

21 hydroxylase

The CYP21A2 gene encodes the human protein, Steroid 21-hydroxylase. This enzyme hydroxylates...

Depression is it genetic

Depression, also referred to as major depression or major depressive disorder, is a psychiatric...


Research and publications:

  15637659   Linkage disequilibrium patterns and tagSNP transferability among European populations.

  17081296   Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits.

  18180755   Family-based association of FKBP5 in bipolar disorder.

  18191112   The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort.

  18349090   Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.

  18597649   Genetic variants in FKBP5 affecting response to antidepressant drug treatment.

  19199039   Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder.

  19455174   Psychobiology and molecular genetics of resilience.

  19540311   Genetics of anxiety and trauma-related disorders.

  19676097   FKBP5 polymorphisms and antidepressant response in geriatric depression.

  19750552   Risk and resilience: genetic and environmental influences on development of the stress response.

  20008943   Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.

  20090668   Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide.

  20393453   Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder.

  20504254   Pharmacogenomics of suicidal events.

  20549395   Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies

  20551900   FKBP5 polymorphisms modify the effects of childhood trauma.

  20709156   Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders.

  20726698   Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals.

  20856915   Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters.

  21112363   Association of FKBP5 gene haplotypes with completed suicide in the Japanese population.

  21172166   Pharmacogenetics of antidepressant response.

  21225419   Gene-environment interactions: early life stress and risk for depressive and anxiety disorders.

  21333900   The role of genetics in IBS

  21448414   Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease

  21536970   Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.

  21788965   Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study examining polymorphisms of the GR and FKBP5 genes.

  21865530   Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study.

  21978546   Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.

  22030708   Genome-wide association study of antidepressant treatment-emergent suicidal ideation.

  22134958   Relationship between FKBP5 polymorphisms and depression symptoms among kidney transplant recipients.

  22213790   Interaction between FKBP5 and childhood trauma and risk of aggressive behavior.

  22738351   Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response.

  22979952   FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity.

  23062294   The role of limbic system irritability in linking history of childhood maltreatment and psychiatric outcomes in low-income, high-risk women: moderation by FK506 binding protein 5 haplotype.

  23707272   Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure.

  23733030   Pharmacogenetics in major depression: a comprehensive meta-analysis.

  24128936   PharmGKB summary: venlafaxine pathway.

  24166410   HPA axis genetic variation, cortisol and psychosis in major depression.

  24603855   FKBP5 moderates alcohol withdrawal severity: human genetic association and functional validation in knockout mice.

  24632812   Transcriptomic analysis of the effects of a fish oil enriched diet on murine brains.

  24658422   Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance.

  24741566   Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy.

  24845178   Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype.

  24856550   FKBP5 polymorphism is associated with major depression but not with bipolar disorder.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25532758   FKBP5 variation is associated with the acute and chronic effects of nicotine.

  26424511   Psychiatric symptoms in adolescents: FKBP5 genotype--early life adversity interaction effects.

  26588823   Association of Epidemiologic Factors and Genetic Variants Influencing Hypothalamic-Pituitary-Adrenocortical Axis Function With Postconcussive Symptoms After Minor Motor Vehicle Collision.

  26630184   Association between FKBP5 Functional Polymorphisms and Completed Suicide.

  26982819   FKBP5 is associated with amygdala volume in the human brain and mood state: A voxel-based morphometry (VBM) study.

  27028297   A Complex Systems Approach to Causal Discovery in Psychiatry.

  27078785   FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study.

  27107574   Impact of polymorphisms in microRNA biogenesis genes on colon cancer risk and microRNA expression levels: a population-based, case-control study.

  27389186   The Interaction between Childhood Bullying and the FKBP5 Gene on Psychotic-Like Experiences and Stress Reactivity in Real Life.

  27448712   Associations between the FKBP5 haplotype, exposure to violence and anxiety in females.

  27485401   Interactive effects of attachment and FKBP5 genotype on emotion regulation and depressive symptoms in school-age children.

  27528460   HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition.

  27552816   The emerging role of the FKBP5 gene polymorphisms in vulnerability-stress model of schizophrenia: further evidence from a Serbian population.

  27601205   Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis.

  27648526   The influence of FKBP5 genotype on expression of FKBP5 and other glucocorticoid-regulated genes, dependent on trauma exposure.

  27721799   Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.

  27754486   Association of FKBP5 polymorphisms and resting-state activity in a frontotemporal-parietal network.

  28002634   FKBP5 polymorphisms influence pre-learning stress-induced alterations of learning and memory.

  28462386   Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury.

  28654774   FKBP5 moderation of the relationship between childhood trauma and maladaptive emotion regulation strategies in adolescents.

  28822116   Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.

  28850857   Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis.

  28889074   Interaction between FKBP5 gene and childhood trauma on psychosis, depression and anxiety symptoms in a non-clinical sample.

  28891785   Attachment style moderates effects of FKBP5 polymorphisms and childhood abuse on post-traumatic stress symptoms: Results from the National Health and Resilience in Veterans Study.

  29101603   Hypothalamic-pituitary-adrenal axis variants and childhood trauma influence anxiety sensitivity in South African adolescents.

  29190830   Reduced functional connectivity of fronto-parietal sustained attention networks in severe childhood abuse.

  29466454   Interaction between FKBP5 variability and recent life events in the anxiety spectrum: Evidence for the differential susceptibility model.

  30524168   Neurocognitive Endophenotypes of Schizophrenia and Bipolar Disorder and Possible Associations with FKBP Variant rs3800373.

  30711865   FKBP5 gene variants and borderline personality disorder.

  30791339   Association between FKBP5 polymorphisms and depressive disorders or suicidal behavior: A systematic review and meta-analysis study.

  31023072   Symptom Science: Advocating for Inclusion of Functional Genetic Polymorphisms.

  31071710   FKBP5 Gene Variants May Modulate Depressive Features in Bipolar Disorder.

  31510784   FKBP5 Genotype Linked to Combined PTSD-Depression Symptom in Chinese Earthquake Survivors.

  31655035   Correlation between hypothalamic-pituitary-adrenal axis gene polymorphisms and posttraumatic stress disorder symptoms.

  31927265   Genetic association of FKBP5 with PTSD in US service members deployed to Iraq and Afghanistan.

  32056869   Interaction between FKBP5 polymorphisms and childhood trauma on depressive symptoms in Chinese adolescents: The moderating role of resilience.

  32093798   Interaction of both positive and negative daily-life experiences with FKBP5 haplotype on psychosis risk.

  32170058   FKBP5 haplotypes and PTSD modulate the resting-state brain activity in Han Chinese adults who lost their only child.

  32547886   Association of FKBP5 polymorphisms with patient susceptibility to coronary artery disease comorbid with depression.

  32576619   Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders.

  32709656   Efficacy, cost-utility and physiological effects of Acceptance and Commitment Therapy (ACT) and Behavioural Activation Treatment for Depression (BATD) in patients with chronic low back pain and depression: study protocol of a randomised, control

  32757697   Further evidence for the association of GAL, GALR1 and NPY1R variants with opioid dependence.

  32892762   Stress-related cognitive style is related to volumetric change of the hippocampus and FK506 binding protein 5 polymorphism in post-traumatic stress disorder.

  33019527   The Pathways between Cortisol-Related Regulation Genes and PTSD Psychotherapy.

  33161050   Association between polymorphisms of FKBP5 gene and suicide attempt in a Mexican population: A case-control study.

  33541187   Interaction of FKBP5 variant rs3800373 and city living alters the neural stress response in the anterior cingulate cortex.

  33742763   Association of FKBP5 gene variants with depression susceptibility: A comprehensive meta-analysis.

  33925151   The Impact of the FKBP5 Gene Polymorphisms on the Relationship between Traumatic Life Events and Psychotic-Like Experiences in Non-Clinical Adults.

  34149370   Influence of FKBP5 Variants and Childhood Trauma on Brain Volume in Non-clinical Individuals.

  35329940   The Moderating Role of the FKBP5 Gene Polymorphisms in the Relationship between Attachment Style, Perceived Stress and Psychotic-like Experiences in Non-Clinical Young Adults.

  35787810   Association of SNPs in the FK-506 binding protein (FKBP5) gene among Han Chinese women with polycystic ovary syndrome.

Serotonin transporter sert

In humans, the SLC6A4 gene encodes a protein referred to as both the sodium-dependent serotonin...

CYP21 deficiency

The inability to synthesize cortisol, known as congenital adrenal hyperplasia (CAH), is responsible...

Dopamine transporter genes

The membrane-bound protein called the dopamine transporter (DAT), also known as the...

en
|
de
|
fr
|
es
|
it
|
ua
|
ru

Support