SNP information rs3761847

Research and publications:

  17804836   TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  18434327   Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

  18648537   A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2

  18794853   Common variants at CD40 and other loci confer risk of rheumatoid arthritis

  18987647   Rheumatoid arthritis: a view of the current genetic landscape

  19116907   Association of the TRAF1/C5 locus with increased mortality, particularly from malignancy or sepsis, in patients with rheumatoid arthritis.

  19180477   Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations

  19336421   Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese.

  19401279   Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis.

  19445664   Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

  19565500   Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis

  19674979   Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

  19714643   TRAF1 polymorphisms associated with rheumatoid arthritis susceptibility in Asians and in Caucasians.

  19849816   Genetics of rheumatic disease.

  19898481   Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

  20017974   Simultaneous analysis of all single-nucleotide polymorphisms in genome-wide association study of rheumatoid arthritis.

  20017985   Adjusting for HLA-DRbeta1 in a genome-wide association analysis of rheumatoid arthritis and related biomarkers.

  20017996   Effect of population stratification on the identification of significant single-nucleotide polymorphisms in genome-wide association studies.

  20018005   Analysis of genome-wide association data by large-scale Bayesian logistic regression.

  20018006   Case-control genome-wide association study of rheumatoid arthritis from Genetic Analysis Workshop 16 using penalized orthogonal-components regression-linear discriminant analysis.

  20018022   Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.

  20018027   Conditional analysis of the major histocompatibility complex in rheumatoid arthritis.

  20018035   A combinatorial approach for detecting gene-gene interaction using multiple traits of Genetic Analysis Workshop 16 rheumatoid arthritis data.

  20018062   Identification of genes and haplotypes that predict rheumatoid arthritis using random forests.

  20018071   Allelic based gene-gene interactions in rheumatoid arthritis.

  20018074   Identifying rheumatoid arthritis susceptibility genes using high-dimensional methods.

  20018075   Genome-wide association study of rheumatoid arthritis by a score test based on wavelet transformation.

  20018090   Comparative analysis of different approaches for dealing with candidate regions in the context of a genome-wide association study.

  20075733   Recent advances in the genetics of rheumatoid arthritis.

  20205706   TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies.

  20233754   Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.

  20309874   Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.

  20453842   Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

  20479942   Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.

  20510233   Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis.

  20691091   Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data.

  20722033   The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21120996   Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans.

  21156761   A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

  21211616   Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.

  21368773   Peripheral blood gene expression profiles in metabolic syndrome, coronary artery disease and type 2 diabetes.

  21492465   Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population.

  21765104   Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.

  21858135   Efficient replication of over 180 genetic associations with self-reported medical data.

  21931699   Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset.

  21980439   A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis.

  22162633   Activation of type I interferon pathway in systemic lupus erythematosus: association with distinct clinical phenotypes.

  22661644   Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.

  22820624   Associations between TNFSF4 and TRAF1-C5 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.

  23226040   Pharmacogenetics of rheumatoid arthritis: Potential targets from susceptibility genes and present therapies.

  23450725   Susceptibility to childhood-onset rheumatoid arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of variants at five genetic loci.

  24068971   Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

  24144456   Associations between TRAF1-C5 gene polymorphisms and rheumatoid arthritis: a meta-analysis.

  24449572   Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

  24917882   Genetic-based prediction of disease traits: prediction is very difficult, especially about the future.

  25025429   Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes.

  25834819   TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthritis response to anti-tumor necrosis factor therapy.

  26504858   Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt.

  26843965   Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis.

  27015630   Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease.

  27092776   A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

  29167514   Common origin of the gelsolin gene variant in 62 Finnish AGel amyloidosis families.

  31530986   Associations of TRAF1/C5 rs10818488 and rs3761847 polymorphisms with genetic susceptibility to rheumatoid arthritis: a case-control study and updated meta-analysis.

  31570557   Association of TRAF1/C5 Locus Polymorphisms with Epilepsy and Clinical Traits in Mexican Patients with Neurocysticercosis.

  32152480   NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium.

  35088123   Genetics of rheumatoid arthritis.

  20018028   Armitage test for genome-wide association analysis: one-sided or two-sided?

  20018053   Genome-wide association scan data for rheumatoid arthritis using Hotelling T2 tests.

  21595938   Polymorphisms associated with rheumatoid arthritis do not protect against Alzheimer's disease.